The crude and age-standardized incidence rate (per 100,000) for mesothelioma in South Korea during the observed (1994–2013) and predicted periods (2014–2033), stratified according to sex.

<p>The arrows indicate the peak incidence rate for mesothelioma. (The peak crude incidence rate does not appear by 2033 in men).</p

The population pyramid, stratified according to sex, for South Korea in 2013 and 2033.

<p>The population pyramid, stratified according to sex, for South Korea in 2013 and 2033.</p

Estimated future incidence of malignant mesothelioma in South Korea: Projection from 2014 to 2033

<div><p>Malignant mesothelioma is a malignant tumor on the pleura or the peritoneum caused mostly by asbestos. Although asbestos is not currently used in South Korea, the incidence of mesothelioma is increasing due to its long latent period. This study predicted the incidence of malignant mesothelioma in South Korea over the next 20 years using an age-period-cohort (APC) model. Data regarding mesothelioma incidence from 1994–2013 were acquired from the Korea Central Cancer Registry (KCCR). Demographic data, including prospective resident data, were acquired from the Korean Statistical Information Service (KOSIS) for 1994–2033. An APC model with Møller’s power-link function was utilized to predict the incidence of mesothelioma. It was predicted that 2,380 and 1,199 new cases of mesothelioma in men and women, respectively, would occur over the next 20 years. For both sexes, the mesothelioma incidence rate was predicted to be greater in 2029–2033 compared to that in 2009–2013 (men, 0.282 vs 0.563; women, 0.155 vs 0.217). For men, the age-standardized incidence rate was predicted to be slightly greater in 2029–2033 relative to the rate in 2009–2013 (0.228 vs 0.235), while the age-standardized incidence rate in women decreased within the same timeframe (0.113 vs 0.109). The changes in mesothelioma incidence were mostly caused by changes in the population structure due to aging and not by changes in the mesothelioma risk ratio. The results of this study project a continuous increase in mesothelioma incidence in South Korea over the next 20 years. Although the projected increase in mesothelioma incidence was not related to an increase in the mesothelioma risk ratio, continuous preventive efforts are necessary to reduce the exposure to asbestos and prevent the trend from worsening.</p></div

Observed (1994–2013) and predicted mesothelioma cases (2029–2033) in South Korea, stratified according to sex.

<p>Observed (1994–2013) and predicted mesothelioma cases (2029–2033) in South Korea, stratified according to sex.</p

The observed and predicted mesothelioma incidence between 2009–2013 and 2029–2033 in South Korea, stratified according to sex, with the corresponding percentage change in the number of cases decomposed into changing risk and demographic components.

<p>The observed and predicted mesothelioma incidence between 2009–2013 and 2029–2033 in South Korea, stratified according to sex, with the corresponding percentage change in the number of cases decomposed into changing risk and demographic components.</p

The age-specific incidence rates of mesothelioma in South Korea for the observed (1994–2013) and predicted periods (2014–2033), stratified according to sex.

<p>The age-specific incidence rates of mesothelioma in South Korea for the observed (1994–2013) and predicted periods (2014–2033), stratified according to sex.</p

The amount of imported and produced asbestos (1975–2008) plotted against the age-standardized and crude incidence rates in South Korea during the observed (1994–2013) and predicted periods (2014–2033).

<p>(The observed incidence rates reflect annual data).</p

Additional file 1: Table S4. of The association of relational and organizational job stress factors with sleep disorder: analysis of the 3rd Korean working conditions survey (2011)

Odds ratio of selected variables and Sleep disorder. (XLSX 14 kb

Additional file 1: of Working hours and self-rated health over 7Â years: gender differences in a Korean longitudinal study

Directed acyclic graph illustrating the hypothesized pathway of working hours to self-rated health and associated covariates. (PDF 81 kb