56 research outputs found

    3D Point Capsule Networks

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    In this paper, we propose 3D point-capsule networks, an auto-encoder designed to process sparse 3D point clouds while preserving spatial arrangements of the input data. 3D capsule networks arise as a direct consequence of our novel unified 3D auto-encoder formulation. Their dynamic routing scheme and the peculiar 2D latent space deployed by our approach bring in improvements for several common point cloud-related tasks, such as object classification, object reconstruction and part segmentation as substantiated by our extensive evaluations. Moreover, it enables new applications such as part interpolation and replacement.Comment: As published in CVPR 2019 (camera ready version), with supplementary materia

    3D Point Capsule Networks

    Get PDF
    In this paper, we propose 3D point-capsule networks, an auto-encoder designed to process sparse 3D point clouds while preserving spatial arrangements of the input data. 3D capsule networks arise as a direct consequence of our novel unified 3D auto-encoder formulation. Their dynamic routing scheme and the peculiar 2D latent space deployed by our approach bring in improvements for several common point cloud-related tasks, such as object classification, object reconstruction and part segmentation as substantiated by our extensive evaluations. Moreover, it enables new applications such as part interpolation and replacement

    Prognostic and Predictive Value of Three DNA Methylation Signatures in Lung Adenocarcinoma

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    Background: Lung adenocarcinoma (LUAD) is the leading cause of cancer-related mortality worldwide. Molecular characterization-based methods hold great promise for improving the diagnostic accuracy and for predicting treatment response. The DNA methylation patterns of LUAD display a great potential as a specific biomarker that will complement invasive biopsy, thus improving early detection. Method: In this study, based on the whole-genome methylation datasets from The Cancer Genome Atlas (TCGA) and several machine learning methods, we evaluated the possibility of DNA methylation signatures for identifying lymph node metastasis of LUAD, differentiating between tumor tissue and normal tissue, and predicting the overall survival (OS) of LUAD patients. Using the regularized logistic regression, we built a classifier based on the 3616 CpG sites to identify the lymph node metastasis of LUAD. Furthermore, a classifier based on 14 CpG sites was established to differentiate between tumor and normal tissues. Using the Least Absolute Shrinkage and Selection Operator (LASSO) Cox regression, we built a 16-CpG-based model to predict the OS of LUAD patients. Results: With the aid of 3616-CpG-based classifier, we were able to identify the lymph node metastatic status of patients directly by the methylation signature from the primary tumor tissues. The 14-CpG-based classifier could differentiate between tumor and normal tissues. The area under the receiver operating characteristic (ROC) curve (AUC) for both classifiers achieved values close to 1, demonstrating the robust classifier effect. The 16-CpG-based model showed independent prognostic value in LUAD patients. Interpretation: These findings will not only facilitate future treatment decisions based on the DNA methylation signatures but also enable additional investigations into the utilization of LUAD DNA methylation pattern by different machine learning methods

    Net volatilization of PAHs from the North Pacific to the Arctic Ocean observed by passive sampling

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    The North Pacific-Arctic Oceans are important compartments for semi-volatile organic compounds’ (SVOCs) global marine inventory, but whether they act as a “source or sink” remains controversial. To study the air-sea exchange and fate of SVOCs during their poleward long-range transport, low-altitude atmosphere and surface seawater were measured for polycyclic aromatic hydrocarbons (PAHs) by passive sampling from July to September in 2014. Gaseous PAH concentrations (0.67–13 ng m−3) were dominated by phenanthrene (Phe) and fluorene (Flu), which displayed an inverse correlation with latitude, as well as a significant linear relationship with partial pressure and inverse temperature. Concentrations of PAHs in seawater (1.8–16 ng L−1) showed regional characteristics, with higher levels near the East Asia and lower values in the Bering Strait. The potential impact from the East Asian monsoon was suggested for gaseous PAHs, which – similar to PAHs in surface seawater - were derived from combustion sources. In addition, the data implied net volatilization of PAHs from seawater into the air along the entire cruise; fluxes displayed a similar pattern to regional and monthly distribution of PAHs in seawater. Our results further emphasized that air-sea exchange is an important process for PAHs in the open marine environments

    ReFusion: Learning Image Fusion from Reconstruction with Learnable Loss via Meta-Learning

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    Image fusion aims to combine information from multiple source images into a single one with more comprehensive informational content. The significant challenges for deep learning-based image fusion algorithms are the lack of a definitive ground truth as well as the corresponding distance measurement, with current manually given loss functions constrain the flexibility of model and generalizability for unified fusion tasks. To overcome these limitations, we introduce a unified image fusion framework based on meta-learning, named ReFusion, which provides a learning paradigm that obtains the optimal fusion loss for various fusion tasks based on reconstructing the source images. Compared to existing methods, ReFusion employs a parameterized loss function, dynamically adjusted by the training framework according to the specific scenario and task. ReFusion is constituted by three components: a fusion module, a loss proposal module, and a source reconstruction module. To ensure the fusion module maximally preserves the information from the source images, enabling the reconstruction of the source images from the fused image, we adopt a meta-learning strategy to train the loss proposal module using reconstruction loss. The update of the fusion module relies on the fusion loss proposed by the loss proposal module. The alternating updates of the three modules mutually facilitate each other, aiming to propose an appropriate fusion loss for different tasks and yield satisfactory fusion results. Extensive experiments demonstrate that ReFusion is capable of adapting to various tasks, including infrared-visible, medical, multi-focus, and multi-exposure image fusion. The code will be released
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