5,223 research outputs found
Immune-inflammatory biomarkers as prognostic factors for immunotherapy in pretreated advanced urinary tract cancer patients: an analysis of the Italian SAUL cohort
Mesoscopic continuous and discrete channels for quantum information transfer
We study the possibility of realizing perfect quantum state transfer in
mesoscopic devices. We discuss the case of the Fano-Anderson model extended to
two impurities. For a channel with an infinite number of degrees of freedom, we
obtain coherent behavior in the case of strong coupling or in weak coupling
off-resonance. For a finite number of degrees of freedom, coherent behavior is
associated to weak coupling and resonance conditions
Characteristics and outcome of BRCA mutated epithelial ovarian cancer patients in Italy: A retrospective multicenter study (MITO 21)
Double dot chain as a macroscopic quantum bit
We consider an array of N quantum dot pairs interacting via Coulomb
interaction between adjacent dots and hopping inside each pair. We show that at
the first order in the ratio of hopping and interaction amplitudes, the array
maps in an effective two level system with energy separation becoming
exponentially small in the macroscopic (large N) limit. Decoherence at zero
temperature is studied in the limit of weak coupling with phonons. In this case
the macroscopic limit is robust with respect to decoherence. Some possible
applications in quantum information processing are discussed.Comment: Phys. Rev. A (in press
High-dose chemotherapy in a patient with coronavirus disease (COVID-19)
none5noopenDe Giorgi U.; Casadei C.; Bronte G.; Altini M.; Martinelli G.De Giorgi, U.; Casadei, C.; Bronte, G.; Altini, M.; Martinelli, G
State of the art about influenza vaccination for advanced cancer patients receiving immune checkpoint inhibitors: When common sense is not enough
Therapeutic challenges for cisplatin-resistant ovarian germ cell tumors
The majority of patients with advanced ovarian germ cell cancer are treated by cisplatin-based chemotherapy. Despite adequate first-line treatment, nearly one third of patients relapse and almost half develop cisplatin-resistant disease, which is often fatal. The treatment of cisplatin-resistant disease is challenging and prognosis remains poor. There are limited data on the efficacy of specific chemotherapeutic regimens, high-dose chemotherapy with autologous progenitor cell support and targeted therapies. The inclusion of patients in clinical trials is strongly recommended, especially in clinical trials on the most frequent male germ cell tumors, to offer wider therapeutic opportunities. Here, we provide an overview of current and potential new treatment options including combination chemotherapy, high-dose chemotherapy and molecular targeted therapies, for patients with cisplatin-resistant ovarian germ cell tumors
post hoc analysis of the effect of baseline characteristics on treatment duration in patients with metastatic castration resistant prostate cancer mcrpc receiving cabazitaxel in the compassionate use cup expanded access programs eap and capristana registry
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