ATV and RAL pharmacokinetic parameters in different dosing strategies.

<p>ATV and RAL pharmacokinetic parameters in different dosing strategies.</p

Patients’ characteristics at baseline.

<p>Patients’ characteristics at baseline.</p

Changes from baseline in main laboratory parameters.

<p>ATV/r or ATV: Boosted or Unboosted Atazanavir; RAL: Raletgravir; ALT: Alanine aminotransferase; HDL: High-density lipoprotein; LDL: Low-density lipoprotein.</p

Reasons for stopping dual therapy before week 96 (n = 132).

<p>Reasons for stopping dual therapy before week 96 (n = 132).</p

Cumulative probability of treatment success according with ritonavir association.

<p>Survival curves by time to loss of virological response analysis, according to virological failure (A) and treatment failure (B). ATV/r or ATV: Boosted or Unboosted Atazanavir, RAL: Raltegravir.</p

Significant predictors associated with virological failure and therapeutic failure.

<p>Significant predictors associated with virological failure and therapeutic failure.</p

Recovery of the CD4+ T cell compartment in CMV seropositive and CMV seronegative HIV-infected patients on first-line cART.

<p>Recovery of the CD4+ T cell compartment in CMV seropositive and CMV seronegative HIV-infected patients on first-line cART.</p

Longitudinal analyses of CD8+ T cell counts in CMV- and CMV+ HIV-infected patients on first-line cART.

<p>100% stacked bar charts illustrate the fraction of patients displaying CD8+ T cell counts ≥830/mm3 (black) and <830/mm3 (white) among all study participants (a) or in patients achieving CD4+ T cell count ≥500/mm3 after 12 months of HIV suppression on cART (b) in CMV- (top) and CMV+ (bottom) patients.</p

Patients’ characteristics at the time of cART initiation.

<p>Patients’ characteristics at the time of cART initiation.</p

Assessment of model calibration: Observed (Kaplan Meier, black) versus predicted (Cox, gray) survival curves.

<p>Assessment of model calibration: Observed (Kaplan Meier, black) versus predicted (Cox, gray) survival curves.</p