Additional file 7: of Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation

Fbw7-induced degradation of STAT3 is more important than other reported tumorigenesis in ABC-DLBCL. A, western blotting showed overexpression of Fbw7 inhibit Stat3 more significant than other reported substrates of Fbw7 including Myc, Notch, Jun, DEK and MCL1. And the results of relative intensity were shown. B, Fbw7 decreases the stability of Stat3 more significant than other reported substrates of Fbw7 including Myc, Notch, Jun, DEK and MCL1. (TIF 680 kb