Characteristics of the sample (N = 2264).

<p>Characteristics of the sample (N = 2264).</p

Multiple logistic regression analysis of respondents’ characteristics and living arrangement preferences.

<p>Multiple logistic regression analysis of respondents’ characteristics and living arrangement preferences.</p

Percentage distribution of respondents’ preferred living arrangements by their characteristics.

<p>Percentage distribution of respondents’ preferred living arrangements by their characteristics.</p

Performance for all the 63 groups of measurements in cross-validation.^*

*<p>Six measurements are represented as following: 1/mono-nucleotide frequencies, 2/di-nucleotide frequencies, 3/mono-codon composition, 4/di-codon composition, 5/mono-amino acid usages, 6/di-amino acid usages.</p>a<p>The boldface letter indicates the group with highest accuracy among the 63 combinations.</p

List of misclassified genes in 10-fold cross-validation.^*

*<p>All the 15 misclassified ORFs (with an average length of 296.6 nucleotides) are small ORFs, which are usually difficult to identify.</p

G-T nucleotide distribution on 1st codon position of all four sets of ORFs.

<p>(a) G-T distribution of 4835 positive and 3515 negative samples in training sets. (b) G-T distribution for 1256 predicted genes and 488 rejected spurious ORFs and all 1744 ORFs are those originally labeled as dubious or uncharacterized by the SGD annotation.</p

Data_Sheet_1_Projecting trends in the disease burden of adult edentulism in China between 2020 and 2030: a systematic study based on the global burden of disease.docx

PurposeThis study was based on the Global Burden of Disease (GBD) database and aimed to analyze the trend of disease burden for complete edentulism in Chinese adults between 1990 and 2030, and to provide valuable information for the development of more effective management and preventive measures.MethodsData on Chinese adults with complete edentulism from 1990 to 2019 was analyzed using GHDx data. Descriptive analyses were used to analyze changes in the prevalence and burden of complete edentulism, gender and age distribution between 1990 and 2019. In addition, we used an autoregressive integrated moving average (ARIMA) model to predict the trend of disease burden for Chinese adults with complete edentulism between 2020 and 2030.ResultsThe incidence, prevalence, and rate of YLDs in adults with complete edentulism in China showed an increasing trend from 1990 to 2019. In 2019, the incidence was 251.20 per 100,000, the prevalence was 4512.78 per 100,000, and the YLDs were 123.44 per 100,000, marking increases of 20.58, 94.18, and 93.12% from 1990. Males experienced a higher increase than females. However, the standardized rates decreased over the same period. The ARIMA model predicts a subsequent upward and then downward trend for all indicators between 2019 and 2030, except for the standardized incidence rate which remained essentially unchanged. Specifically, the incidence is predicted to decrease from 388.93 to 314.40 per 100,000, prevalence from 4512.78 to 3049.70 per 100,000, and YLDs from 123.44 to 103.44 per 100,000. The standardized prevalence and YLDs rates are also expected to decrease.ConclusionThe burden of complete edentulism in China is projected to show an increasing trend from 2020 to 2022 and a decreasing trend from 2023 to 2030. Despite the decline in the burden of disease associated with complete edentulism in China, many problems remain to be solved.</p

Ratiometric Fluorescent Sensor Based on Hydrogen-Bond Triggering the Internal Filter Effect for Enzyme-Free and Visual Monitoring Pesticide Residues

Real-time/field sensing techniques to keep track of methyl parathion (MP) are crucial to human health. In this work, a ratiometric fluorescence probe was constructed by integrating green carbon dots and CdTe quantum dots (CdTe QDs) for highly selective quantitative detection of MP. Under alkaline conditions, MP can be rapidly hydrolyzed to produce p-nitrophenol (p-NP); the instantaneous reaction that strengthens the hydrogen bond results in the internal filter effect between the carbon dots and p-NP, which quenches green fluorescence, thus leading to an obvious and immediate change from green to red. The probe displayed a sensitive limit of detection of 8.9 nM and exhibited a significant linear response to MP residue concentrations in the range of 0–100 M. In addition, we have created a brand-new smartphone-based intelligent detection tool by measuring the RGB value of the fluorescent probe solution and the matching paper-based sensor, and we are able to visually and quantitatively identify the levels of MP residues present in water, apples, and vegetables. This ratiometric fluorescence sensing method can realize rapid visual and quantitative detection of MP residues, which provides a more reliable guarantee promising strategy for constructing a risk detection technique for traces without enzymes

Attitudes Toward Catastrophe

In light of climate change and other global threats, policy commentators sometimes urge that society should be more concerned about catastrophes. This paper reflects on what society’s attitude toward low-probability, high-impact events is, or should be. We first argue that catastrophe risk can be conceived of as a spread in the distribution of losses. Based on this conception, we review studies from decision sciences, psychology, and behavioral economics that elicit people’s attitudes toward various social risks. We find more evidence against than in favor of catastrophe aversion—the preference for a mean-preserving contraction of the loss distribution—and discuss a number of possible behavioral explanations. Next, we turn to social choice theory and examine how various social welfare functions handle catastrophe risk. We explain why catastrophe aversion may be in conflict with equity concerns and other-regarding preferences. Finally, we discuss current approaches to evaluate and regulate catastrophe risk

Additional file 3: Table S2. of Genomic, proteomic and bioinformatic analysis of two temperate phages in Roseobacter clade bacteria isolated from the deep-sea water

Hierarchical clustering of (pro)phages and prophage-like elements among 423 bacterial genomes in terms of gene content, which was based on SiliX homology clustering. Green represents the presence of gene. (XLS 291 kb