4,149 research outputs found

    A Malfunctioning System

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    Preferences, trust and willingness to pay for food information: An analysis of the Italian Market

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    Lack of consumer trust and communication strategies are probably the main determinants of information failure in modern food markets. This study attempts to tackle these aspects affecting the quality of food information by investigating questions related to what topics are more relevant to consumers, who should disseminate trustful food information, and how communication should be conveyed. Primary data were collected both through qualitative (in depth interviews and focus groups) and quantitative research. Quantitative research was conducted by means of a questionnaire administered in 2006-2007 to a sample of Italian respondents using both a web and a traditional mail survey. Reading preferences, willingness to pay and trust towards public and private sources conveying information through a hypothetical food magazine were assessed combining factor analysis, choice modelling and a criterion-based market segmentation. The study shows that reading preferences of Italian consumers can be summarized along three dimensions: agro-food system, enjoyment and wellness. Furthermore, willingness to pay for receiving food-related information is influenced by trust towards the type of publisher, which plays also a key role in market segmentation together with socio-demographic and economic variables such as gender, age, presence of children and income. Policy implications of these findings are discussed.food information, trust, preference heterogeneity, segmentation, Italy, Food Consumption/Nutrition/Food Safety, D12, D18, D89, Q18,

    Cognitive fluctuations in connection to disgraphia a comparison of Alzheimer's disease with dementia Lewy bodies

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    Background: The purpose of the present study was to examine the relationship between cognitive impairment and the performance of handwritten scripts presented as “letter-writing” to a close relative by patients with dementia Lewy bodies (DLB), as fluctuations of the symptoms phase, and in a matched group of patients with Alzheimer’s disease (AD). The degree of writing disability and personal, spatial, and temporal orientation was compared in these two groups. Design and methods: Fourteen simple questions, designed in a form that could be utilized by any general practitioner in order to document the level of cognitive functioning of each patient, were presented to 30 AD patients and 26 DLB patients. The initial cognition test was designated PQ1. The patients were examined on tests of letter-writing ability. Directly after the letter-writing, the list of 14 questions presented in PQ1 was presented again in a repeated procedure that was designated PQ2. The difference between these two measures (PQ1 – PQ2) was designated D∆. This test of letter-writing ability and cognitive performance was administered over 19 days. Results: Several markedly strong relationships between dysgraphia and several measures of cognitive performance in AD patients and DLB patients were observed, but the deterioration of performance from PQ1 to PQ2 over all test days were markedly significant in AD patients and not significant in DLB patients. It is possible that in graphic expression even by patients diagnosed with moderate to relatively severe AD and DLB there remains some residual capacity for understanding and intention that may be expressed. Furthermore, the deterioration in performance and the differences noted in AD and DLB patients may be due to the different speed at which the process of the protein degradation occurs for functional modification of synapses. Conclusion: Our method can be used as part of neuropsychological tests to differentiate the diagnosis between AD and DL

    Segmenting the Italian coffee market: marketing opportunities for economic agents working along the international coffee chain

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    Globalization, either directly or indirectly (e.g. through structural adjustment reforms), has called for profound changes in the previously existing institutional order. Some changes adversely impacted the production and market environment of many coffee producers in developing countries resulting in more risky and less remunerative coffee transactions. This paper focuses on customization of a tropical commodity, fair-trade coffee, as an approach to mitigating the effects of worsened market conditions for small-scale coffee producers in less developed countries. fair-trade labeling is viewed as a form of “de-commodification” of coffee through product differentiation on ethical grounds. This is significant not only as a solution to the market failure caused by pervasive information asymmetries along the supply chain, but also as a means of revitalizing the agricultural-commodity-based trade of less developed countries (LDCs) that has been languishing under globalization. More specifically, fair-trade is an example of how the same strategy adopted by developed countries’ producers/ processors (i.e. the sequence product differentiation - institutional certification - advertisement) can be used by LDC producers to increase the reputation content of their outputs by transforming them from mere commodities into “decommodified” (i.e. customized and more reputed) goods. The resulting segmentation of the world coffee market makes possible to meet the demand by consumers with preference for this “(ethically) customized” coffee and to transfer a share of the accruing economic rents backward to the Fair-trade coffee producers in LDCs. It should however be stressed that this outcome cannot be taken for granted since investments are needed to promote the required institutional innovations. In Italy FTC is a niche market with very few private brands selling this product. However, an increase of FTC market share could be a big commercial opportunity for farmers in LDCs and other economic agents involved along the international coffee chain. Hence, this research explores consumers’ knowledge of labels promoting quality products, consumption coffee habits, brand loyalty, willingness to pay and market segmentation according to the heterogeneity of preferences for coffee products. The latter was assessed developing a D-efficient design where stimuli refinement was tested during two focus groups.fair-trade coffee, product decommodification, choice experiments, International Relations/Trade,

    Blood-Brain Barrier Breakdown by Combined Detection of Circulating Tumor and Endothelial Cells in Liquid Biopsy

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    Blood-brain barrier breakdown occurring in glioblastoma is a temporary condition often denounced by contrast enhancement upon neurological examination. This condition is useful to increase the intracranial concentration of anti-cancer drugs. The prognosis of glioblastoma and its resistance to conventional therapy has stimulated interest in the search of biomarkers able to unmask and monitor brain barrier breakdown to calibrate the treatment. Despite numerous studies had evidenced the role of circulating tumor and endothelial cells to monitor brain tumor, the mechanism of tumor cells release in the bloodstream and its prognostic significance remain unclear. In this chapter, we want to furnish an update on the relationship between the vascular damage occurring during glioblastoma disease and the reactivity of innate immunity focusing on the cytokines network. Our aim is answer to the question: when and why the liquid biopsy is useful in glioblastoma disease

    Low-cost, high-resolution, fault-robust position and speed estimation for PMSM drives operating in safety-critical systems

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    In this paper it is shown how to obtain a low-cost, high-resolution and fault-robust position sensing system for permanent magnet synchronous motor drives operating in safety-critical systems, by combining high-frequency signal injection with binary Hall-effect sensors. It is shown that the position error signal obtained via high-frequency signal injection can be merged easily into the quantization-harmonic-decoupling vector tracking observer used to process the Hall-effect sensor signals. The resulting algorithm provides accurate, high-resolution estimates of speed and position throughout the entire speed range; compared to state-of-the-art drives using Hall-effect sensors alone, the low speed performance is greatly improved in healthy conditions and also following position sensor faults. It is envisaged that such a sensing system can be successfully used in applications requiring IEC 61508 SIL 3 or ISO 26262 ASIL D compliance, due to its extremely high mean time to failure and to the very fast recovery of the drive following Hall-effect sensor faults at low speeds. Extensive simulation and experimental results are provided on a 3.7 kW permanent magnet drive
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