Quantile-Quantile(QQ) plots on SNP set enrichment.

<p>QQ-plots of SNP set enrichment test. Solid line represents normal distribution and black dots represent data distribution of p-values for eSNPs representing genes within the gene set of interest. Deviation of the data from the solid line indicates a non-normal distribution. Plots are shown for the top ranking gene sets A: published mRNA profiling signatures from infarcted tissue and B: implicated causal genes from the Global Lipid Genetics GWAS Consortium.</p

Overall Population Trends: Incidence Trends per 100 000 Youth.

<p>Overall Population Trends: Incidence Trends per 100 000 Youth.</p

Population Trends by Predictor of Initiation- Gender Specific Trends: Incidence per 100 000 Youth.

<p>Population Trends by Predictor of Initiation- Gender Specific Trends: Incidence per 100 000 Youth.</p

Population Trends by Predictor of Initiation- Age Group Specific Trends: Incidence per 100 000 Youth.

<p>Population Trends by Predictor of Initiation- Age Group Specific Trends: Incidence per 100 000 Youth.</p

Beneficiary Baseline Characteristics By Study Period.

<p>SD, Standard deviation; NE, Northeast; NC, North Central</p><p>^a Mean monthly percentage of population with medical encounters in the 3-months prior</p><p>Beneficiary Baseline Characteristics By Study Period.</p

Monthly Mean Incidence (95% CI) Per 100 000 Commercially Insured Children: Overall and by Predictor Subgroups

<p>CI, Confidence Interval; NE, Northeastern; NC, North Central</p><p>^a Based on medical encounters in the 3-months prior to index drug date</p><p>^b Patients who visited “neither” specialties were omitted from table</p><p>Monthly Mean Incidence (95% CI) Per 100 000 Commercially Insured Children: Overall and by Predictor Subgroups</p

Population Trends by Predictor of Initiation- Physician Specialty Trends: Incidence per 100 000 Youth.

<p>Population Trends by Predictor of Initiation- Physician Specialty Trends: Incidence per 100 000 Youth.</p

Regional plots for the association of SNPs with MI in the region of <i>QKI</i>.

<p>Regional plots for the association of SNPs with MI in the region of <i>QKI</i>.</p

Study design for identification and validation of SNPs associated with MI and CHD.

<p>Study design for identification and validation of SNPs associated with MI and CHD.</p

Association of the known SNPs for coronary artery disease with incident MI and CHD in Stage I.

<p>Association of the known SNPs for coronary artery disease with incident MI and CHD in Stage I.</p