Teaching Geometry and Surfaces Evaluation Through Graphic Representation and Dynamic Paper Models

To make the geometrical cognitive process more interactive, we produced teaching aids (tangible models, graphic tablets) that help students in visualiz-ing their geometrical-analytical investigations of the architectural artifacts and enhance their spatial prefiguration and critical form-reading skills, three-dimensional thinking and geometrical reading of shapes. Then, we looked for a medium suitable to create simple three-dimensional models, not only observable, like virtual models, not only tangible, like physical models pro-posed in the design studios, but also dynamic, using multiple media and lan-guages in the same training message. As an example, we present here an interdisciplinary lesson between Cal-culus and Architectural Drawing and Survey Laboratory about developable surfaces, experimented on first year students of the bachelor program in Ar-chitecture. The lesson is based on the use of a graphic tablet and some ori-gami inspired models: it summarizes the geometric description of a pyramid and a cloister vault of equal height and equal orthographic projection on the horizontal plane. We saw that tackling the same topic in both teaching contexts is not a use-less overlap, but a stimulus to compare different languages and methods. 2D and 3D paper models of artifacts – and of projective reduction from 3D to the plane – aid spatial intuition and the subtle exercise of controlling mental images which replace artifacts, turning 3D configurations into signifying im-ages. Moreover, this experience stimulates reading and evaluation of the drawn geometry (ruled surfaces, projections, developments), increasing criti-cal sense in reading the built environmen

Genome Analysis of the Anaerobic Thermohalophilic Bacterium Halothermothrix orenii

Halothermothirx orenii is a strictly anaerobic thermohalophilic bacterium isolated from sediment of a Tunisian salt lake. It belongs to the order Halanaerobiales in the phylum Firmicutes. The complete sequence revealed that the genome consists of one circular chromosome of 2578146 bps encoding 2451 predicted genes. This is the first genome sequence of an organism belonging to the Haloanaerobiales. Features of both Gram positive and Gram negative bacteria were identified with the presence of both a sporulating mechanism typical of Firmicutes and a characteristic Gram negative lipopolysaccharide being the most prominent. Protein sequence analyses and metabolic reconstruction reveal a unique combination of strategies for thermophilic and halophilic adaptation. H. orenii can serve as a model organism for the study of the evolution of the Gram negative phenotype as well as the adaptation under thermohalophilic conditions and the development of biotechnological applications under conditions that require high temperatures and high salt concentrations

Insight from an Italian Delphi Consensus on EVAR feasibility outside the instruction for use: the SAFE EVAR Study

BACKGROUND: The SAfety and FEasibility of standard EVAR outside the instruction for use (SAFE-EVAR) Study was designed to define the attitude of Italian vascular surgeons towards the use of standard endovascular repair (EVAR) for infrarenal abdominal aortic aneurysm (AAA) outside the instruction for use (IFU) through a Delphi consensus endorsed by the Italian Society of Vascular and Endovascular Surgery (Societa Italiana di Chirurgia Vascolare ed Endovascolare - SICVE). METHODS: A questionnaire consisting of 26 statements was developed, validated by an 18 -member Advisory Board, and then sent to 600 Italian vascular surgeons. The Delphi process was structured in three subsequent rounds which took place between April and June 2023. In the first two rounds, respondents could indicate one of the following five degrees of agreement: 1) strongly agree; 2) partially agree; 3) neither agree nor disagree; 4) partially disagree; 5) strongly disagree; while in the third round only three different choices were proposed: 1) agree; 2) neither agree nor disagree; 3) disagree. We considered the consensus reached when >70% of respondents agreed on one of the options. After the conclusion of each round, a report describing the percentage distribution of the answers was sent to all the participants. RESULTS: Two -hundred -forty-four (40.6%) Italian Vascular Surgeons agreed to participate the first round of the Delphi Consensus; the second and the third rounds of the Delphi collected 230 responders (94.3% of the first -round responders). Four statements (15.4%) reached a consensus in the first rounds. Among the 22 remaining statements, one more consensus (3.8%) was achieved in the second round. Finally, seven more statements (26.9%) reached a consensus in the simplified last round. Globally, a consensus was reached for almost half of the proposed statements (46.1%). CONCLUSIONS: The relatively low consensus rate obtained in this Delphi seems to confirm the discrepancy between Guideline recommendations and daily clinical practice. The data collected could represent the source for a possible guidelines' revision and the proposal of specific Good Practice Points in all those aspects with only little evidence available