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Single machine scheduling to minimize batch delivery and job earliness penalties
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The J-triplet Cooper pairing with magnetic dipolar interactions
Recently, cold atomic Fermi gases with the large magnetic dipolar interaction
have been laser cooled down to quantum degeneracy. Different from
electric-dipoles which are classic vectors, atomic magnetic dipoles are
quantum-mechanical matrix operators proportional to the hyperfine-spin of
atoms, thus provide rich opportunities to investigate exotic many-body physics.
Furthermore, unlike anisotropic electric dipolar gases, unpolarized magnetic
dipolar systems are isotropic under simultaneous spin-orbit rotation. These
features give rise to a robust mechanism for a novel pairing symmetry: orbital
p-wave (L=1) spin triplet (S=1) pairing with total angular momentum of the
Cooper pair J=1. This pairing is markedly different from both the He-B
phase in which J=0 and the He- phase in which is not conserved. It
is also different from the p-wave pairing in the single-component electric
dipolar systems in which the spin degree of freedom is frozen
Magnetars and pulsars: a missing link
There is growing evidence that soft gamma-ray repeaters (SGRs) and anomalous
X-ray pulsars (AXPs) are isolated neutron stars with superstrong magnetic
fields, i.e., magnetars, marking them a distinguished species from the
conventional species of spindown-powered isolated neutron stars, i.e., radio
pulsars. The current arguments in favor of the magnetar interpretation of
SGR/AXP phenomenology will be outlined, and the two energy sources in
magnetars, i.e. a magnetic dissipation energy and a spindown energy, will be
reviewed. I will then discuss a missing link between magnetars and pulsars,
i.e., lack of the observational evidence of the spindown-powered behaviors in
known magnetars. Some recent theoretical efforts in studying such behaviors
will be reviewed along with some predictions testable in the near future.Comment: Invited talk at the Sixth Pacific Rim Conference on Stellar
Astrophysics, a tribute to Helmut A. Abt, July 11-17, 2002, Xi'an. To appear
in the proceedings (eds. K. S. Cheng, K. C. Leung & T. P. Li
Stable Panoramic Views Facilitate Snap-Shot Like Memories for Spatial Reorientation in Homing Pigeons
Following spatial disorientation, animals can reorient themselves by relying on geometric cues (metric and sense) specified both by the macroscopic surface layout of an enclosed space and prominent visual landmarks in arrays. Whether spatial reorientation in arrays of landmarks is based on explicit representation of the geometric cues is a matter of debate. Here we trained homing pigeons (Columba livia) to locate a food-reward in a rectangular array of four identical or differently coloured pipes provided with four openings, only one of which allowed the birds to have access to the reward. Pigeons were trained either with a stable or a variable position of the opening on pipes, so that they could view the array either from the same or a variable perspective. Explicit mapping of configural geometry would predict successful reorientation irrespective of access condition. In contrast, we found that a stable view of the array facilitated spatial learning in homing pigeons, likely through the formation of snapshot-like memories
Study protocol : the empirical investigation of methods to correct for measurement error in biobanks with dietary assessment
Peer reviewedPublisher PD
Subitizing with Variational Autoencoders
Numerosity, the number of objects in a set, is a basic property of a given
visual scene. Many animals develop the perceptual ability to subitize: the
near-instantaneous identification of the numerosity in small sets of visual
items. In computer vision, it has been shown that numerosity emerges as a
statistical property in neural networks during unsupervised learning from
simple synthetic images. In this work, we focus on more complex natural images
using unsupervised hierarchical neural networks. Specifically, we show that
variational autoencoders are able to spontaneously perform subitizing after
training without supervision on a large amount images from the Salient Object
Subitizing dataset. While our method is unable to outperform supervised
convolutional networks for subitizing, we observe that the networks learn to
encode numerosity as basic visual property. Moreover, we find that the learned
representations are likely invariant to object area; an observation in
alignment with studies on biological neural networks in cognitive neuroscience
Determinants of adults' intention to vaccinate against pandemic swine flu
This article has been made available through the Brunel Open Access Publishing Fund.This article has been made available through the Brunel Open Access Publishing Fund.Background: Vaccination is one of the cornerstones of controlling an influenza pandemic. To optimise vaccination rates in the general population, ways of identifying determinants that influence decisions to have or not to have a vaccination need to be understood. Therefore, this study aimed to predict intention to have a swine influenza
vaccination in an adult population in the UK. An extension of the Theory of Planned Behaviour provided the theoretical framework for the study.
Methods: Three hundred and sixty two adults from the UK, who were not in vaccination priority groups, completed either an online (n = 306) or pen and paper (n = 56) questionnaire. Data were collected from 30th October 2009, just after swine flu vaccination became available in the UK, and concluded on 31st December 2009. The main outcome of interest was future swine flu vaccination intentions.
Results: The extended Theory of Planned Behaviour predicted 60% of adults’ intention to have a swine flu vaccination with attitude, subjective norm, perceived control, anticipating feelings of regret (the impact of missing a vaccination opportunity), intention to have a seasonal vaccine this year, one perceived barrier: “I cannot be bothered to get a swine flu vaccination” and two perceived benefits: “vaccination decreases my chance of getting swine flu or its complications” and “if I get vaccinated for swine flu, I will decrease the frequency of having to consult my doctor,” being significant predictors of intention. Black British were less likely to intend to have a vaccination compared to Asian or White respondents.
Conclusions: Theoretical frameworks which identify determinants that influence decisions to have a pandemic influenza vaccination are useful. The implications of this research are discussed with a view to maximising any future pandemic influenza vaccination uptake using theoretically-driven applications.This article is available through the Brunel Open Access Publishing Fund
Definition of the σW regulon of Bacillus subtilis in the absence of stress
Bacteria employ extracytoplasmic function (ECF) sigma factors for their responses to environmental stresses. Despite intensive research, the molecular dissection of ECF sigma factor regulons has remained a major challenge due to overlaps in the ECF sigma factor-regulated genes and the stimuli that activate the different ECF sigma factors. Here we have employed tiling arrays to single out the ECF σW regulon of the Gram-positive bacterium Bacillus subtilis from the overlapping ECF σX, σY, and σM regulons. For this purpose, we profiled the transcriptome of a B. subtilis sigW mutant under non-stress conditions to select candidate genes that are strictly σW-regulated. Under these conditions, σW exhibits a basal level of activity. Subsequently, we verified the σW-dependency of candidate genes by comparing their transcript profiles to transcriptome data obtained with the parental B. subtilis strain 168 grown under 104 different conditions, including relevant stress conditions, such as salt shock. In addition, we investigated the transcriptomes of rasP or prsW mutant strains that lack the proteases involved in the degradation of the σW anti-sigma factor RsiW and subsequent activation of the σW-regulon. Taken together, our studies identify 89 genes as being strictly σW-regulated, including several genes for non-coding RNAs. The effects of rasP or prsW mutations on the expression of σW-dependent genes were relatively mild, which implies that σW-dependent transcription under non-stress conditions is not strictly related to RasP and PrsW. Lastly, we show that the pleiotropic phenotype of rasP mutant cells, which have defects in competence development, protein secretion and membrane protein production, is not mirrored in the transcript profile of these cells. This implies that RasP is not only important for transcriptional regulation via σW, but that this membrane protease also exerts other important post-transcriptional regulatory functions
Lepton Acceleration in Pulsar Wind Nebulae
Pulsar Wind Nebulae (PWNe) act as calorimeters for the relativistic pair
winds emanating from within the pulsar light cylinder. Their radiative
dissipation in various wavebands is significantly different from that of their
pulsar central engines: the broadband spectra of PWNe possess characteristics
distinct from those of pulsars, thereby demanding a site of lepton acceleration
remote from the pulsar magnetosphere. A principal candidate for this locale is
the pulsar wind termination shock, a putatively highly-oblique,
ultra-relativistic MHD discontinuity. This paper summarizes key characteristics
of relativistic shock acceleration germane to PWNe, using predominantly Monte
Carlo simulation techniques that compare well with semi-analytic solutions of
the diffusion-convection equation. The array of potential spectral indices for
the pair distribution function is explored, defining how these depend
critically on the parameters of the turbulent plasma in the shock environs.
Injection efficiencies into the acceleration process are also addressed.
Informative constraints on the frequency of particle scattering and the level
of field turbulence are identified using the multiwavelength observations of
selected PWNe. These suggest that the termination shock can be comfortably
invoked as a principal injector of energetic leptons into PWNe without
resorting to unrealistic properties for the shock layer turbulence or MHD
structure.Comment: 19 pages, 5 figures, invited review to appear in Proc. of the
inaugural ICREA Workshop on "The High-Energy Emission from Pulsars and their
Systems" (2010), eds. N. Rea and D. Torres, (Springer Astrophysics and Space
Science series
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