A Study on the Ideological Connotation and Significance of Agricultural Poetry in the Northern Song Dynasty

The agrarian-related poems of the Northern Song Dynasty are far from the realistic creation tradition of the Book of Songs, the Yuefu folk songs of the Han Dynasty, “those who are hungry sing about their food, those who are working about their work”, and the realistic spirit of Du Fu’s “Three officials” and “three different” and Bai Juyi’s New Yuefu Movement, “Only songs live the people’s disease”. Through multiple contrast techniques, they fully show the miserable fate of the peasants under the heavy pressure of land, taxation, labor and other systems in the Northern Song Dynasty. It exposes the social situation of extreme disparity between the rich and the poor and sharp contradictions between classes, and expresses the complex feelings of compassion, hatred and guilt of scholars and literati. Influenced by the social culture of the Song Dynasty, the agriculture-related poems of the Northern Song Dynasty also showed the creative tendency of argumentation and prose culture, which was different from the previous poetry, and demonstrated the unique artistic style of the Song poetry

Dynamics of glass phases in the two-dimensional gauge glass model

Large-scale simulations have been performed on the current-driven two-dimensional XY gauge glass model with resistively-shunted-junction dynamics. It is observed that the linear resistivity at low temperatures tends to zero, providing strong evidence of glass transition at finite temperature. Dynamic scaling analysis demonstrates that perfect collapses of current-voltage data can be achieved with the glass transition temperature $T_{g}=0.22$, the correlation length critical exponent $\nu =1.8$, and the dynamic critical exponent $z=2.0$. A genuine continuous depinning transition is found at zero temperature. For creeping at low temperatures, critical exponents are evaluated and a non-Arrhenius creep motion is observed in the glass phase.Comment: 10 pages, 6 figure

Flux-lattice melting in LaO1−x_{1-x}Fx_{x}FeAs: first-principles prediction

We report the theoretical study of the flux-lattice melting in the novel iron-based superconductor $LaO_{0.9}F_{0.1}FeAs$ and $LaO_{0.925}F_{0.075}FeAs$. Using the Hypernetted-Chain closure and an efficient algorithm, we calculate the two-dimensional one-component plasma pair distribution functions, static structure factors and direct correlation functions at various temperatures. The Hansen-Verlet freezing criterion is shown to be valid for vortex-liquid freezing in type-II superconductors. Flux-lattice meting lines for $LaO_{0.9}F_{0.1}FeAs$ and $LaO_{0.925}F_{0.075}FeAs$ are predicted through the combination of the density functional theory and the mean-field substrate approach.Comment: 5 pages, 4 figures, to appear in Phys. Rev.

Thymol inhibits cell migration and invasion by downregulating the activation of PI3K/AKT and ERK pathways in human colon cancer cells

Purpose: To assess the anti-metastasis effects of thymol on human colorectal cancer cells. Methods: Human colorectal adenocarcinoma cell HT29 was incubated with varying concentrations of thymol. Cell viability, migration and invasion were determined by 3-(4, 5-dimethylthiazol-2-yl)-2, 5dipheny-tetrazoliumbromide (MTT) and Transwell assays, respectively. Matrix metalloproteinase-2 and 9 (MMP-2 and MMP-9) were analyzed by gel zymogram assay. Epithelial-mesenchymal transition (EMT)-associated gene expression and signaling pathway were analyzed using real-time quantitative polymerase chain reaction (PCR) and Western blotting, respectively. Results: Thymol was significantly inhibited migration and invasion of HT29 cell (p < 0.01) and also markedly reduced the activity of matrix degrading enzymes MMP-2 and MMP-9 (p < 0.01). Moreover, the epithelial marker, E-cadherin, was elevated, while mesenchymal markers (vimentin and α-SMA), and associated transcription factors (snail and slug) decreased after thymol treatment (p < 0.01). In addition, thymol inhibited the phosphorylation of PI3K/AKT and ERK pathways (p < 0.01). Conclusion: Thymol efficiently attenuates cell migration and invasion by decreasing EMT and downregulating the activation of PI3K/AKT and ERK signaling pathways in colorectal adenocarcinoma cells. It is, thus, a potential candidate drug for the management of colorectal cancer. Keywords: Thymol, Colorectal cancer, Anti-metastasis, Epithelial-mesenchymal transition, Vimentin, PI3K/AKT and ERK pathwa