Investigation and Countermeasures of Chinese Physical Education Teachers\u27 Teaching Status under Integration of Sports and Education

School physical education is an ideal place to improve the physical fitness of young people. In China, school physical education includes physical education and health education. Physical education teacher is an important factor that influences the quality of school physical education. This study was based on the government policy of “deepening the comprehensive reform in the field of education”. The purposes were to investigating the current situation of Chinese physical education teachers’ teaching, providing suggestions and directions for the improvement of their teaching, and subsequently improving students’ physical health. This study adopted the following methods: literature review, questionnaire and interview methods. The participants of this study were physical education teachers who were recruited through random sampling across the country. Interview and questionnaires were conducted at three occasions: before class, during class, and after class. In-depth quantitative and qualitative analyses were conducted to understand the cognition and teaching status of physical education teachers. Data analysis results showed that teachers’ academic qualifications was positively correlated with their understanding of theoretical knowledge such as curriculum standards (p \u3c 0.05, r = 0.468). For class implementation, only about 23.3% teachers’ teaching practice met the requirement of China’s healthy physical education curriculum model in term of the amount of physical activity. There was a significant difference between the length of teaching and the curriculum arrangement (p \u3c 0.01). Finally, for after-school activities, the organization of after-school physical activities was mainly focusing on sport practices, and varsity team training accounted for 61% of these sport practices. Many different types of reasons were raised by the teacher about the factors restricting physical exercise after school. Under the background of policies advocating the integration of sports and education, it is important to raise the professional standards of being a physical education teacher. Current physical education teachers should learn how to implement the “Chinese Health Sports Curriculum Model”. More professional development opportunities should be provided for physical education teachers in terms of teaching methods, curriculum development, and after-school physical activity program development. Physical education teachers should learn the factors that restricts students from participating in after-school physical activities and the strategies to address these restricting factors

A free-standing graphene-polypyrrole hybrid paper via electropolymerization with an enhanced areal capacitance

Here we developed a free-standing reduced graphene oxide (rGO)-polypyrrole (PPy) hybrid paper via electropolymerization on a paper-like graphene gel. This flexible hybrid paper displayed a uniform layered structure with PPy coated onto the graphene layers. A high areal mass of 2.7 mg cm−2 could be obtained. It delivered a greatly enhanced areal capacitance of 440 mF cm−2 at 0.5 A g−1, in contrast to that 151∼198.5 mF cm−2 previously reported for graphene paper or polypyrrole-graphene paper. It can retain ∼81% of the initial capacitance at a high current density of 6 A g−1. The combined high flexibility with outstanding electrochemical performance, makes such novel hybrid paper a promising electrode for flexible supercapacitors

Toward biodegradable Mg-air bioelectric batteries composed of silk fibroin-polypyrrole film

Biodegradable active implantable devices can be used to diagnose and/or treat disease and eventually disappear without surgical removal. If an external energy source is required for effective operation then a biocompatible and biodegradable battery would be ideal. In this study, a partially biodegradable Mg-air bioelectric battery (biobattery) is demonstrated using a silk fibroin-polypyrrole (SF-PPy) film cathode coupled with bioresorbable Mg alloy anode in phosphate buffered saline (PBS) electrolyte. PPy is chemically coated onto one side of the silk substrate. SF-PPy film shows a conductivity of ≈1.1 S cm−1 and a mild catalytic activity toward oxygen reduction. It degrades in a concentrated buffered protease XIV solution, with a weight loss of 82% after 15 d. The assembled Mg-air biobattery exhibits a discharge capacity up to 3.79 mA h cm−2 at a current of 10 μA cm−2 at room temperature, offering a specific energy density of ≈4.70 mW h cm−2. This novel partially biodegradable battery provides another step along the route to biodegradable batteries

Dual Defense: Adversarial, Traceable, and Invisible Robust Watermarking against Face Swapping

The malicious applications of deep forgery, represented by face swapping, have introduced security threats such as misinformation dissemination and identity fraud. While some research has proposed the use of robust watermarking methods to trace the copyright of facial images for post-event traceability, these methods cannot effectively prevent the generation of forgeries at the source and curb their dissemination. To address this problem, we propose a novel comprehensive active defense mechanism that combines traceability and adversariality, called Dual Defense. Dual Defense invisibly embeds a single robust watermark within the target face to actively respond to sudden cases of malicious face swapping. It disrupts the output of the face swapping model while maintaining the integrity of watermark information throughout the entire dissemination process. This allows for watermark extraction at any stage of image tracking for traceability. Specifically, we introduce a watermark embedding network based on original-domain feature impersonation attack. This network learns robust adversarial features of target facial images and embeds watermarks, seeking a well-balanced trade-off between watermark invisibility, adversariality, and traceability through perceptual adversarial encoding strategies. Extensive experiments demonstrate that Dual Defense achieves optimal overall defense success rates and exhibits promising universality in anti-face swapping tasks and dataset generalization ability. It maintains impressive adversariality and traceability in both original and robust settings, surpassing current forgery defense methods that possess only one of these capabilities, including CMUA-Watermark, Anti-Forgery, FakeTagger, or PGD methods

Tripterygium glycosides for safely controlling disease activity in systemic lupus erythematosus: a systematic review with meta-analysis and trial sequential analysis

Background: Tripterygium glycosides have been used to treat systemic lupus erythematosus (SLE) for a long time, showing the effects of immune regulation. We aimed to evaluate the benefits and risks of Tripterygium Glycosides Tablets (TGT) for patients with SLE.Methods: We searched electronic databases and clinical trial registries for relevant randomized controlled trials (RCTs). We identified eligible RCTs and assessed risk of bias. We conducted a meta-analysis to estimate the pooled effects. The Trial Sequential Analysis (TSA) 0.9.5.10 software was used to verify the reliability of the results.Results: Eight RCTs encompassing 538 patients with SLE were included. TGT combined with conventional treatments (CTs) was superior to CTs alone in reducing lupus activity (MD = −1.66, 95% CI = −2.07 to −1.26, p < 0.00001, low-certainty evidence) and improving overall response rate (ORR) (RR = 1.21, 95% CI = 1.11 to 1.32, p < 0.0001, moderate-certainty evidence). The robustness of the results was confirmed by TSA. Regarding safety, there was no statistical difference in the overall incidence of adverse reactions between the two groups.Conclusion: In patients with SLE, TGT might safely reduce disease activity. However, further high-quality studies are needed to firmly establish the clinical efficacy of TGT.Systematic Review Registration:https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022300474; Identifier: CRD42022300474

Visualizing the Localized Electrons of a Kagome Flat Band

Destructive interference between electron wavefunctions on the two-dimensional (2D) kagome lattice induces an electronic flat band, which could host a variety of interesting many-body quantum states. Key to realize these proposals is to demonstrate the real space localization of kagome flat band electrons. In particular, the extent to which the often more complex lattice structure and orbital composition of realistic materials counteract the localizing effect of destructive interference, described by the 2D kagome lattice model, is hitherto unknown. We used scanning tunneling microscopy (STM) to visualize the non-trivial Wannier states of a kagome flat band at the surface of CoSn, a kagome metal. We find that the local density of states associated with the flat bands of CoSn is localized at the center of the kagome lattice, consistent with theoretical expectations for their corresponding Wannier states. Our results show that these states exhibit an extremely small localization length of two to three angstroms concomitant with a strongly renormalized quasiparticle velocity, which is comparable to that of moir\'e superlattices. Hence, interaction effects in the flat bands of CoSn could be much more significant than previously thought. Our findings provide fundamental insight into the electronic properties of kagome metals and are a key step for future research on emergent many-body states in transition metal based kagome materials

A novel intelligent adaptive control of laser-based ground thermal test

AbstractLaser heating technology is a type of potential and attractive space heat flux simulation technology, which is characterized by high heating rate, controlled spatial intensity distribution and rapid response. However, the controlled plant is nonlinear, time-varying and uncertainty when implementing the laser-based heat flux simulation. In this paper, a novel intelligent adaptive controller based on proportion–integration–differentiation (PID) type fuzzy logic is proposed to improve the performance of laser-based ground thermal test. The temperature range of thermal cycles is more than 200K in many instances. In order to improve the adaptability of controller, output scaling factors are real time adjusted while the thermal test is underway. The initial values of scaling factors are optimized using a stochastic hybrid particle swarm optimization (H-PSO) algorithm. A validating system has been established in the laboratory. The performance of the proposed controller is evaluated through extensive experiments under different operating conditions (reference and load disturbance). The results show that the proposed adaptive controller performs remarkably better compared to the conventional PID (PID) controller and the conventional PID type fuzzy (F-PID) controller considering performance indicators of overshoot, settling time and steady state error for laser-based ground thermal test. It is a reliable tool for effective temperature control of laser-based ground thermal test

Mycoplasma hyorhinis infection in gastric carcinoma and its effects on the malignant phenotypes of gastric cancer cells

<p>Abstract</p> <p>Background</p> <p><it>Mycoplasma hyorhinis </it>infection has been postulated to play a role in the development of several types of cancer, but the direct evidence and mechanism remained to be determined.</p> <p>Methods</p> <p>Immunohistochemistry assay and nested polymerase-chain reaction (PCR) were performed to examine the <it>mycoplasma hyorhinis </it>infection in gastric cancer tissues. Statistical analysis was used to check the association between mycoplasma infection and clinicopathologic parameters. Transwell chamber assay and metastasis assay were used to evaluate <it>mycoplasma hyorhinis</it>' effects on metastasis in vitro and in vivo. <it>Mycoplasma hyorhinis</it>-induced extracellular signal-regulated kinase (ERK) and epidermal growth factor receptor (EGFR) activation were investigated by Western blot.</p> <p>Results</p> <p>My<it>coplasma hyorhinis </it>infection in gastric cancer tissues was revealed and statistical analysis indicated a significant association between mycoplasma infections and lymph node metastasis, Lauren's Classification, TNM stage, and age of the patients. <it>Mycoplasma hyorhinis </it>promoted tumor cell migration, invasion and metastasis <it>in vitro </it>and <it>in vivo</it>, which was possibly associated with the enhanced phosphorylation of EGFR and ERK1/2. The antibody against p37 protein of <it>Mycoplasma hyorhinis </it>could inhibit the migration of the infected cells.</p> <p>Conclusions</p> <p>The infection of <it>m</it>y<it>coplasma hyorhinis </it>may contribute to the development of gastric cancer and <it>Mycoplasma hyorhinis</it>-induced malignant phenotypes were possibly mediated by p37.</p

Hawthorn Procyanidins Regulate Lipid Metabolism through the AMPK/SREBP-1c Signaling Pathway

Objective: To investigate the effect of hawthorn procyanidins (HPC) on lipid metabolism and its mechanism by regulating the AMP-activated protein kinase/sterol regulatory element binding protein-1c (AMPK/SREBP-1c) signaling pathway. Methods: Sixty rats were randomly divided into six groups (n = 10) blank control (BC), hyperlipidemia model (HM), low-, medium-, and high-dose HPC (HPC-LD, HPC-MD, and HPC-HD) and fenofibrate positive control (FP). The contents of triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) in the serum and liver homogenate were measured by commercial kits. Hematoxylin eosin (HE) staining was used to observe hepatic histopathological changes. The mRNA expression levels of AMPK, SREBP-1c, glycerol-3-phosphate acyltransferase-1 (GPAT1), acetyl CoA carboxylase (ACC), fatty acid synthase (FAS), carnitine palmitoyltransterase-1 (CPT1) and peroxisome proliferator activated receptor γ coactivator-1α (PGC-1α) in the liver were measured by quantitative real-time polymerase chain reaction (PCR). Western blotting was used to detect the protein expression of p-AMPK, SREBP-1c, GPAT1, ACC, FAS, CPT1 and PGC-1α in the liver. Results: After seven weeks of feeding on a high-fat diet, body mass, liver mass and liver index significantly increased compared with the control group fed on a basal diet (P < 0.05 or < 0.01). Compared with the HM group, the contents of TG, TC and LDL-C in serum and liver homogenate in the HPC-HD and FP groups significantly decreased, and the content of HDL-C significantly increased (P < 0.01); the effect of HPC on lipid content in serum and liver homogenate was dose-dependent. After prophylactic intervention with HPC, the steatosis of hepatocytes was gradually improved with an increase in the dosage of HPC. Compared with the HM group, the AMPK mRNA expression and p-AMPK protein expression in liver tissues in the HPC-HD and FP groups significantly increased (P < 0.01), and the mRNA and protein expression of SREBP-1c, GPAT1, ACC and FAS significantly decreased (P < 0.01), and the mRNA and protein expression of CPT1 and PGC-1α significantly increased in the liver (P < 0.01). Conclusion: HPC can effectively improve lipid metabolism in hyperlipidemic rats, which may be related to the regulation of the AMPK/SREBP-1c signaling pathway