26 research outputs found

    5-Lipoxygenase Metabolic Contributions to NSAID-Induced Organ Toxicity

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    De l'emploi des anesthésiques durant l'accouchement

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    Doctorat en sciences médicalesinfo:eu-repo/semantics/nonPublishe

    Extreme U–Th Disequilibrium in Rift-Related Basalts, Rhyolites and Granophyric Granite and the Timescale of Rhyolite Generation, Intrusion and Crystallization at Alid Volcanic Center, Eritrea

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    Rhyolite pumices and co-erupted granophyric (granite) xenoliths yield evidence for rapid magma generation and crystallization prior to their eruption at 15·2 ± 2·9 ka at the Alid volcanic center in the Danikil Depression, Eritrea. Whole-rock U and Th isotopic analyses show 230Th excesses up to 50% in basalts <10 000 years old from the surrounding Oss lava fields. The 15 ka rhyolites also have 30–40% 230Th excesses. Similarity in U–Th disequilibrium, and in Sr, Nd, and Pb isotopic values, implies that the rhyolites are mostly differentiated from the local basaltic magma. Given the (230Th/232Th) ratio of the young basalts, and presumably the underlying mantle, the (230Th/232Th) ratio of the rhyolites upon eruption could be generated by in situ decay in about 50 000 years. Limited (5%) assimilation of old crust would hasten the lowering of (230Th/232Th) and allow the process to take place in as little as 30 000 years. Final crystallization of the Alid granophyre occurred rapidly and at shallow depths at 20–25 ka, as confirmed by analyses of mineral separates and ion microprobe data on individual zircons. Evidently, 30 000–50 000 years were required for extraction of basalt from its mantle source region, subsequent crystallization and melt extraction to form silicic magmas, and final crystallization of the shallow intrusion. The granophyre was then ejected during eruption of the comagmatic rhyolites

    Preliminary conceptual design of an electronuclear system for space applications

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    International audienceThe purpose of this paper is to present a preliminary conceptual design of a nuclear power system for space applications. This design was produced within the framework of a collaboration between CNES and CEA. The targeted electrical power of the system is 10 kWe for a period of at least 10 years. The scalability towards larger (30 kWe) and lower (about 1 kWe) power has been investigated. The system must be technologically “affordable” and robust over a 10-year horizon, which de facto eliminates the choice of too innovative and unqualified technologies in conditions representative of the missions; the system must be able to be launched in Ariane 6 while respecting the launcher mass and size capacities. Given the intermediate power level targeted and the potential use of the system on the Moon or Mars, the CEA favored design options associated with a compact and monolithic radiator (allowing it to be landed) rather than minimizing the system mass. Taking into account the desired characteristics for the nuclear power system, the CEA proposes main conceptual design features which includes: a thermal spectrum core whose fuel is UO2_2 enriched to 19.75% in U235^{235}, zirconium fuel cladding, a zirconium hydride (ZrH2_2) moderator, and a beryllium reflector. The proposed shield is made of tungsten and lithium hydride (LiH). A core cooling system made up of 150 steel heat pipes operating with a sodium–potassium alloy (NaK) has been pre-designed and a thermoelectric energy converter made up of SiGe thermo-elements (hot temperature of 950 K and cold temperature of 700 K) generates electrical power. A “hot” carbon composite radiator lined with titanium NaK heat pipes rejects the heat of the system. This system has intrinsic redundancies conferred by the heat pipes and the large number of thermo-elements of the converter as well as high passivity, in particular in its ability to adapt its power to electricity demand. In its version limited to 10 kWe, the system whose height is about 5 m, enables to keep a height of 13 m for a payload to be launched in the Ariane 6 fairing and its mass is estimated at about 2 tons. To access a version of the system capable of producing 30 kWe, an additional mass estimated at around 1 ton is to be expected as well as a lower useful height in the fairing under the system, which would then be 10 m
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