To reorient is easier than to orient: An on-line algorithm for reorientation of graphs

We define an on-line (incremental) algorithm that, given a (possibly infinite) pseudo-transitive oriented graph, produces a transitive reorientation. This implies that a theorem of Ghouila-Houri is provable in RCA_0 and hence is computably true

Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy in high myopia: a prospective clinical study

BACKGROUND: To study the effect of prophylactic application of mitomycin-C on haze formation in photorefractive keratectomy (PRK) for high myopia. METHODS: Fifty-four eyes of 28 myopic patients were enrolled in this prospective study. All eyes were operated by PRK followed by 0.02% mitomycin-C application for two minutes and washed with 20 ml normal saline afterwards. All eyes were examined thoroughly on the first 7 days and one month after surgery; 48 eyes (88.9%) at 3 and 6 months postoperatively. Hanna grading (in the scale of 0 to 4+) was used for assessment of corneal haze. RESULTS: The mean spherical equivalent refraction (SE) was -7.08 diopters (D) ± 1.11 (SD) preoperatively. Six months after surgery, 37 eyes (77.1%) achieved an uncorrected visual acuity (UCVA) of 20/20 or better, all eyes had a UCVA of 20/40 or better and 45 (93.7%) eyes had an SE within ± 1.00D. One month postoperatively, 2 eyes (3.7%) had grade 0.5+ of haze, while at 3 and 6 months after surgery no visited eye had haze at all. All eyes had a best corrected visual acuity (BCVA) of 20/40 or better and there were no lost lines in BCVA by 6 months after surgery. In spatial frequencies of 6 and 12 cycles per degree contrast sensitivity had decreased immediately after PRK and it had increased 1.5 lines by the 6(th )postoperative month compared to the preoperative data. CONCLUSIONS: The results show the efficacy of mitomycin-C in preventing corneal haze after treatment of high myopia with PRK. This method- PRK + mitomycin-C – can be considered an alternative treatment for myopic patients whose corneal thicknesses are inadequate for laser in situ keratomileusis (LASIK). However, the results should be confirmed in longer follow-ups

Concept design of low frequency telescope for CMB B-mode polarization satellite LiteBIRD

LiteBIRD has been selected as JAXA’s strategic large mission in the 2020s, to observe the cosmic microwave background (CMB) B-mode polarization over the full sky at large angular scales. The challenges of LiteBIRD are the wide field-of-view (FoV) and broadband capabilities of millimeter-wave polarization measurements, which are derived from the system requirements. The possible paths of stray light increase with a wider FoV and the far sidelobe knowledge of -56 dB is a challenging optical requirement. A crossed-Dragone configuration was chosen for the low frequency telescope (LFT : 34–161 GHz), one of LiteBIRD’s onboard telescopes. It has a wide field-of-view (18° x 9°) with an aperture of 400 mm in diameter, corresponding to an angular resolution of about 30 arcminutes around 100 GHz. The focal ratio f/3.0 and the crossing angle of the optical axes of 90◦ are chosen after an extensive study of the stray light. The primary and secondary reflectors have rectangular shapes with serrations to reduce the diffraction pattern from the edges of the mirrors. The reflectors and structure are made of aluminum to proportionally contract from warm down to the operating temperature at 5 K. A 1/4 scaled model of the LFT has been developed to validate the wide field-of-view design and to demonstrate the reduced far sidelobes. A polarization modulation unit (PMU), realized with a half-wave plate (HWP) is placed in front of the aperture stop, the entrance pupil of this system. A large focal plane with approximately 1000 AlMn TES detectors and frequency multiplexing SQUID amplifiers is cooled to 100 mK. The lens and sinuous antennas have broadband capability. Performance specifications of the LFT and an outline of the proposed verification plan are presented

LiteBIRD satellite: JAXA's new strategic L-class mission for all-sky surveys of cosmic microwave background polarization

LiteBIRD, the Lite (Light) satellite for the study of B-mode polarization and Inflation from cosmic background Radiation Detection, is a space mission for primordial cosmology and fundamental physics. JAXA selected LiteBIRD in May 2019 as a strategic large-class (L-class) mission, with its expected launch in the late 2020s using JAXA's H3 rocket. LiteBIRD plans to map the cosmic microwave background (CMB) polarization over the full sky with unprecedented precision. Its main scientific objective is to carry out a definitive search for the signal from cosmic inflation, either making a discovery or ruling out well-motivated inflationary models. The measurements of LiteBIRD will also provide us with an insight into the quantum nature of gravity and other new physics beyond the standard models of particle physics and cosmology. To this end, LiteBIRD will perform full-sky surveys for three years at the Sun-Earth Lagrangian point L2 for 15 frequency bands between 34 and 448 GHz with three telescopes, to achieve a total sensitivity of 2.16 μK-arcmin with a typical angular resolution of 0.5° at 100 GHz. We provide an overview of the LiteBIRD project, including scientific objectives, mission requirements, top-level system requirements, operation concept, and expected scientific outcomes

Overview of the medium and high frequency telescopes of the LiteBIRD space mission

LiteBIRD is a JAXA-led Strategic Large-Class mission designed to search for the existence of the primordial gravitational waves produced during the inflationary phase of the Universe, through the measurements of their imprint onto the polarization of the cosmic microwave background (CMB). These measurements, requiring unprecedented sensitivity, will be performed over the full sky, at large angular scales, and over 15 frequency bands from 34 GHz to 448 GHz. The LiteBIRD instruments consist of three telescopes, namely the Low-, Medium-and High-Frequency Telescope (respectively LFT, MFT and HFT). We present in this paper an overview of the design of the Medium-Frequency Telescope (89{224 GHz) and the High-Frequency Telescope (166{448 GHz), the so-called MHFT, under European responsibility, which are two cryogenic refractive telescopes cooled down to 5 K. They include a continuous rotating half-wave plate as the first optical element, two high-density polyethylene (HDPE) lenses and more than three thousand transition-edge sensor (TES) detectors cooled to 100 mK. We provide an overview of the concept design and the remaining specific challenges that we have to face in order to achieve the scientific goals of LiteBIRD

Considerazioni sull’applicazione delle lenti a contatto in diabetici.

Gli AA valutano retrospettivamente le problematiche corneali in pazienti diabetici portatori di lenti a contatto Sono inoltre espresse considerazioni sull’applicazione delle lenti a contatto in diabetici

PARTO VAGINALE DOPO TAGLIO CESAREO: RICERCA FENOMENOLOGICA ERMENEUTICA

Background: Contextually to the actual increase in the percentage of worldwide caesarian section, the topic of VBAC (Vaginal Birth after Caesarean) assumes a specific significance. In the literature a large number of articles estimates the quantitative features of the problem, taking into consideration the risks and the benefits, the predictive success factors, the inclusion and exclusion criteria, the guidelines about the pregnancy and childbirth support. There are, however, only few qualitative studies about woman past during the previous caesarian, about the reason leading to the VBAC choice and the vaginal birth experience. Aim of the Study: Finding the reason why a previous caesarian delivery woman chooses to give birth through a vaginal way, instead of repeating a caesarian section, analyzing at the meantime the previous caesarian section past, the difficulties in the relationships with health professionals and with the relatives during the choice, the perceived advantages and disadvantages due to the fact of having given birth through a vaginal way. The secondary purpose is the analysis and the comparison between the procedures used in two third level hospitals in the Lombardia area but also considering the Evidence Based Practice. Methods: The women, who have taken part in the report, have been identified through a retrospective analysis of the nosological report at Clinica Ostetrica L.Mangiagalli and at ICP Buzzi. The analysis is based on the fact that these women are all characterized by a physiological or operative vaginal birth after caesarean section and by an alive and vital newborn, in a period which goes from 4 weeks to 6 months from the birth date. Among these, 16 women have answered to a semi-structured questionnaire that they have filled in at the telephone or by e-mail. At a later stage, the results have been examined by means of a fenomenologic - ermeneutic approach, which has led to identify 20 categories referable to five themes. The valuation of the helpful procedures at both ward is based on the observation of the intra-hospital records devoted to VBAC, on informative and supporting materials, which consent the participation in the VBAC.Results: The women responses highlight the topics: \u201cthe women past after previous caesarian section\u201d, \u201cthe explanation of the women choice\u201d, \u201cthe vaginal birth women past after caesarian\u201d, \u201cpeople around me..\u201d, \u201cthe comparison between the experiences\u201d. In this particular case, women often do not accept and are not pleased with their caesarean experience (with differences between planned and compelling caesarean); meanwhile the VBAC is appraised because of the emotional intensity, even though it is physically difficult for the pain suffered. It is extremely important for women to feel active and birth key player, also to have the opportunity to choose natural childbirth and, at the same time, the convenience of the childbirth. Mother desires and fears emerge together with the pain and the postpartum topic (an analysis about the main difficulties of the two different kind of birth is present). The main reasons leading to the choice of a VBAC are the curiosity of natural vaginal birth emotions, the need to be more active and live better the postpartum, the necessity to share the experience with the husband and the newborn. All the interviewed women feel well liked by professionals during pregnancy, meanwhile during labor 3 women have been frustrated, criticized and they remained lonely. The husband is always a help and an optimal fellow. In contrast with the clinical practice it is highlighted how counseling is not always good realized, how reports are partially consisted with the international guidelines, how professionals show an insufficient application of these reports using a medicalized and interventionist support, sometimes based on defensive medicine. Conclusion: Related to VBAC it is always necessary to consider women experience along with best practice, in order to guarantee a safe and custom assistance during pregnancy (in particular for counseling, which should start fromthe women desires and from the women experience), childbirth and postpartum. Practical Relevance: In order to encourage the VBAC practice and to reduce unessential caesarean, it is important to work for informing women, for conveying about this opportunity and increasing people\u2019s awareness about decisions, for training and updating the professional knowledge, and for a more custom, natural and continuous assistance during pregnancy, childbirth and postnatal period

Influence of co-payment levels on patient and surgeon acceptance of advanced technology intraocular lenses.

PURPOSE: To investigate patients' willingness to pay for advanced technology intraocular lenses and surgeons' willingness to recommend them. METHODS: In this study, 370 cataract surgeons and 700 patients undergoing cataract surgery from seven countries underwent online interviews in which they were shown unbranded profiles of three advanced technology intraocular lenses (ie, biconvex toric aspheric optic, symmetric biconvex diffractive optic, and biconvex diffractive aspheric toric) and asked to indicate their willingness to accept (for patients) or suggest (for surgeons) each lens. Acceptance was assessed assuming there was either no co-payment or co-payments of €500 to €1,500 +15%. RESULTS: All three lenses were widely accepted by patients, with 68% to 99% indicating acceptance when there was no co-payment. In contrast, surgeons' willingness to suggest them was markedly lower (20% to 43%). Both patients' acceptance of the lenses and surgeons' willingness to suggest them decreased with increasing co-payment levels to 19% to 74% (patients) and 5% to 31% (surgeons) at the highest co-payment levels. CONCLUSIONS: There is a marked discrepancy between patients' acceptance of the three lenses and surgeons' willingness to suggest them. Although patients' acceptance is high, it decreases with increasing out-of-pocket expenditure. Manufacturers should communicate the relative benefits and costs of their lenses to both surgeons and patients

Influence of co-payment levels on patient and surgeon acceptance of advanced technology intraocular lenses.

PURPOSE: To investigate patients' willingness to pay for advanced technology intraocular lenses and surgeons' willingness to recommend them. METHODS: In this study, 370 cataract surgeons and 700 patients undergoing cataract surgery from seven countries underwent online interviews in which they were shown unbranded profiles of three advanced technology intraocular lenses (ie, biconvex toric aspheric optic, symmetric biconvex diffractive optic, and biconvex diffractive aspheric toric) and asked to indicate their willingness to accept (for patients) or suggest (for surgeons) each lens. Acceptance was assessed assuming there was either no co-payment or co-payments of €500 to €1,500 +15%. RESULTS: All three lenses were widely accepted by patients, with 68% to 99% indicating acceptance when there was no co-payment. In contrast, surgeons' willingness to suggest them was markedly lower (20% to 43%). Both patients' acceptance of the lenses and surgeons' willingness to suggest them decreased with increasing co-payment levels to 19% to 74% (patients) and 5% to 31% (surgeons) at the highest co-payment levels. CONCLUSIONS: There is a marked discrepancy between patients' acceptance of the three lenses and surgeons' willingness to suggest them. Although patients' acceptance is high, it decreases with increasing out-of-pocket expenditure. Manufacturers should communicate the relative benefits and costs of their lenses to both surgeons and patients