Correlation between HOXA7 and HOXA9 (A) and JAG2 and HLF (B) gene expression in human AML analyzed with TaqMan Low Density Array (TLDA).

<p>Spearman rank correlation analysis was done on the log ratio values obtained from the TLDA assay and calculated with the 2^−ΔΔCT method (n = 34).</p

Venn diagram of genes significantly activated (A) or repressed (B) in Sca1+, Lin- BM cells expressing the ND13, NA10 or ND13(N51S) mutant fusion genes compared to GFP control.

<p>Venn diagram of genes significantly activated (A) or repressed (B) in Sca1+, Lin- BM cells expressing the ND13, NA10 or ND13(N51S) mutant fusion genes compared to GFP control.</p

Genes changed by NA10 and ND13 but not by the ND13(N51S) mutant compared to the GFP control.

<p>Genes changed by NA10 and ND13 but not by the ND13(N51S) mutant compared to the GFP control.</p

Gene expression levels in human AML relative to normal bone marrow.

<p>Gene expression levels in human AML relative to normal bone marrow.</p

Validation of microarray results with quantitative RT-PCR on unamplified RNA.

<p>Fold changes are calculated against an empty MIG control and <i>Gapdh</i> as endogenous control gene.</p