4 research outputs found
Management of Anticoagulation Theraphy (DOAC) for Patient Scheduled for Pacemaker/Defibrillator Insertion
Comfort and ergonomics evaluation of a checkout workstation
The ergonomic principles to the design processes, workplace and organization, has to be applied not only to respond to legal requirements, but also for answer to the companies' needs for pursuing a business logic. This paper shows a cheap and effective method to acquire workplaces, work-cycles and workers-postures, in a supermarket, in order to analyze how cashiers move them-selves into their workspace, with their own tools and devices and do their jobs. Photo and video acquisition has been done to acquire postures and movements by DARTFISH® software; DELMIA® software was used to model humans postures, workstation and interactions. Simulation results were processed by CaMAN® software for evaluating comfort indexes both for each task and globally. Lastly, results have been correlated to subjective perceptions through experimental tests, in order to validate the comfort model
Comparison of the Implantable Cardiac Monitor Reveal LINQ Versus Reveal XT in Young Patients
Epicardial Adipose Tissue and IL-13 Response to Myocardial Injury Drives Left Ventricular Remodeling After ST Elevation Myocardial Infarction
Introduction: Left ventricular (LV) remodeling after ST-segment elevation myocardial infarction (STEMI) is explained only in part by the infarct size, and the inter-patient variability may be ascribed to different inflammatory response to myocardial injury. Epicardial adipose tissue (EAT) is a source of inflammatory mediators which directly modulates the myocardium. EAT increase is associated to several cardiovascular diseases; however, its response to myocardial injury is currently unknown. Among inflammatory mediators, IL-13 seems to play protective role in LV regeneration, but its variations after STEMI have not been described yet. Purpose: In the present study we analyzed the association between infarct-related changes of EAT and IL-13 in post-STEMI LV remodeling. Methods: We enrolled 100 patients with STEMI undergoing primary angioplasty. At the enrolment (T0) and after 3 months (T1), we measured EAT thickness by echocardiography and circulating levels of IL-13 by ELISA. Results: At T1, the 60% of patients displayed increased EAT thickness (ΔEAT > 0). ΔEAT was directly associated to LV end-diastolic volume (r = 0.42; p = 0.014), LV end-systolic volume (r = 0.42; p = 0.013) and worse LV ejection fraction (LVEF) at T1 (r = -0.44; p = 0.0094), independently of the infarct size. In the overall population IL-13 levels significantly decreased at T1 (p = 0.0002). The ΔIL-13 was directly associated to ΔLVEF (r = 0.42; p = 0.017) and inversely related to ΔEAT (r = -0.51; p = 0.022), thus suggesting a protective role for IL-13. Conclusion: The variability of STEMI-induced "inflammatory response" may be associated to the post-infarct LV remodeling. ΔEAT thickness and ΔIL-13 levels could be novel prognostic markers in STEMI patients