Almost sure convergence for the maxima of strongly dependent stationary Gaussian vector sequences

AbstractIn this paper, we prove the almost sure limit theorem of the maxima for a kind of strongly dependent stationary Gaussian vector sequences

Analysis of methane-producing and metabolizing archaeal and bacterial communities in sediments of the northern South China Sea and coastal Mai Po Nature Reserve revealed by PCR amplification of mcrA and pmoA genes

Communities of methanogens, anaerobic methanotrophic archaea and aerobic methanotrophic bacteria (MOB) were compared by profiling polymerase chain reaction (PCR)-amplified products of mcrA and pmoA genes encoded by methyl-coenzyme M reductase alpha subunit and particulate methane monooxygenase alpha subunit, respectively, in sediments of northern South China Sea (nSCS) and Mai Po mangrove wetland. Community structures representing by mcrA gene based on 12 clone libraries from nSCS showed separate clusters indicating niche specificity, while, Methanomicrobiales, Methanosarcinales clades 1,2, and Methanomassiliicoccus-like groups of methanogens were the most abundant groups in nSCS sediment samples. Novel clusters specific to the SCS were identified and the phylogeny of mcrA gene-harboring archaea was updated. Quantitative polymerase chain reaction was used to detect mcrA gene abundance in all samples: similar abundance of mcrA gene in the surface layers of mangrove (3.4∼3.9 × 106 copies per gram dry weight) and of intertidal mudflat (5.5∼5.8 × 106 copies per gram dry weight) was observed, but higher abundance (6.9 × 106 to 1.02 × 108 copies per gram dry weight) was found in subsurface samples of both sediment types. Aerobic MOB were more abundant in surface layers (6.7∼11.1 × 105 copies per gram dry weight) than the subsurface layers (1.2∼5.9 × 105 copies per gram dry weight) based on pmoA gene. Mangrove surface layers harbored more abundant pmoA gene than intertidal mudflat, but less pmoA genes in the subsurface layers. Meanwhile, it is also noted that in surface layers of all samples, more pmoA gene copies were detected than the subsurface layers. Reedbed rhizosphere exhibited the highest gene abundance of mcrA gene (8.51 × 108 copies per gram dry weight) and pmoA gene (1.56 × 107 copies per gram dry weight). This study investigated the prokaryotic communities responsible for methane cycling in both marine and coastal wetland ecosystems, showing the distribution characteristics of mcrA gene-harboring communities in nSCS and stratification of mcrA and pmoA gene diversity and abundance in the Mai Po Nature Reserve

Collaborative Planning for Catching and Transporting Objects in Unstructured Environments

Multi-robot teams have attracted attention from industry and academia for their ability to perform collaborative tasks in unstructured environments, such as wilderness rescue and collaborative transportation.In this paper, we propose a trajectory planning method for a non-holonomic robotic team with collaboration in unstructured environments.For the adaptive state collaboration of a robot team to catch and transport targets to be rescued using a net, we model the process of catching the falling target with a net in a continuous and differentiable form.This enables the robot team to fully exploit the kinematic potential, thereby adaptively catching the target in an appropriate state.Furthermore, the size safety and topological safety of the net, resulting from the collaborative support of the robots, are guaranteed through geometric constraints.We integrate our algorithm on a car-like robot team and test it in simulations and real-world experiments to validate our performance.Our method is compared to state-of-the-art multi-vehicle trajectory planning methods, demonstrating significant performance in efficiency and trajectory quality

AbRSA: A robust tool for antibody numbering

The remarkable progress in cancer immunotherapy in recentâ years has led to the heat of great development for therapeutic antibodies. Antibody numbering, which standardizes a residue index at each position of an antibody variable domain, is an important step in immunoinformatic analysis. It provides an equivalent index for the comparison of sequences or structures, which is particularly valuable for antibody modeling and engineering. However, due to the extremely high diversity of antibody sequences, antibodyâ numbering tools cannot work in all cases. This article introduces a new antibodyâ numbering tool named AbRSA, which integrates heuristic knowledge of regionâ specific features into sequence mapping to enhance the robustness. The benchmarks demonstrate that, AbRSA exhibits robust performance in numbering sequences with diverse lengths and patterns compared with the stateâ ofâ theâ art tools. AbRSA offers a userâ friendly interface for antibody numbering, complementarityâ determining region delimitation, and 3D structure rendering. It is freely available at http://cao.labshare.cn/AbRSA.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/150604/1/pro3633.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/150604/2/pro3633-sup-0001-Suppinfo.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/150604/3/pro3633_am.pd

A young woman with atypical McCune–Albright syndrome and the difficult road to recovery: a case report

BackgroundFiber dysplasia is a complex condition that presents with various clinical manifestations, such as deformity, dysfunction, pathological fractures, and endocrine disorders. McCune–Albright syndrome (MAS) is a rare subtype of fiber dysplasia. This article reports a case of atypical McCune–Albright syndrome in a patient with a femoral neck fracture.Case presentationA patient with atypical McCune–Albright syndrome sustained a right femoral neck fracture and underwent multiple treatments, including total hip replacement, intravenous infusion of zoledronic acid, oral calcium supplementation, right supracondylar osteotomy, orthopedic surgery, plate and screw internal fixation for a left femoral shaft fracture, and removal of the right femoral plate. The patient also developed a submaxillary infection complicated by mandibular osteonecrosis.ConclusionPatients with MAS may experience rare complications as a result of their unique condition, regardless of whether they receive drug or surgical treatment. Therefore, personalized drug regimens and feasible surgical options are necessary