44 research outputs found
On the landing of a giant grouper at Paradeep and strandings of dead turtles along Paradeep and Puri coasts, Orissa
A giant grouper, Eplnephalus lanceolatus (Bloch)
(Promicrops lanceolatus) locally called 'Kaibaley' measuring
202 cm in total length was landed at Paradeep on
18-12-'97 by a trawler operated 12 km south of
Paradeep (Fig.
Heavy landings of prawn (Metapenaeus dobsoni) at Paradeep along the Orissa coast
Heavy landings of M.dobsoni, popularly called 'khopra'
in Oriya were noticed at Paradeep centre during the off
season in March and April 1995 in the trawl net. It was
the largest catch ever landed in the last 10 years. It
is also the most important species of prawn in the
commercial fishery of Orissa coast. The unusual
fishery occurred when the prawns migrated to the
shallow waters and were caught by the trawler
On a whale shark landed at Paradeep, Orrisa
On 4-11-'97 a female whale shark, Rhlniodon
typus measuring 6.69 m in total length was landed at
Paradeep, Jagatsinghpur District, Oriss
Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA
Hypermutation and class switch recombination of immunoglobulin genes are antigen-activated mechanisms triggered by AID, a cytidine deaminase. AID deaminates cytidine residues in the DNA of the variable and the switch regions of the immunoglobulin locus. The resulting uracil induces error-prone DNA synthesis in the case of hypermutation or DNA breaks that activate non-homologous recombination in the case of class-switch recombination. In vitro studies have demonstrated that AID deaminates single-stranded but not double-stranded substrates unless AID is in a complex with RPA and the substrate is actively undergoing transcription. However, it is not clear whether AID deaminates its substrates primarily as a monomer or as a higher order oligomer. To examine the oligomerization state of AID alone and in the presence of single stranded DNA substrates of various structures, including loops embedded in double-stranded DNA, we used atomic force microscopy (AFM) to visualize AID protein alone or in complex with DNA. Surprisingly, AFM results indicate that most AID molecules exist as a monomer and that it binds single-stranded DNA substrates as a monomer at concentrations where efficient deamination of single-stranded DNA substrates occur. The rate of deamination, under conditions of excess and limiting protein, also imply that AID can deaminate single-stranded substrates as a monomer. These results imply that non-phosphorylated AID is catalytically active as a monomer on single stranded DNA in vitro, including single-stranded DNA found in loops similar to those transiently formed in the immunoglobulin switch regions during transcription
Effect of Obesity on Acute Ozone-Induced Changes in Airway Function, Reactivity, and Inflammation in Adult Females
We previously observed greater ozone-induced lung function decrements in obese than non-obese women. Animal models suggest that obesity enhances ozone-induced airway reactivity and inflammation. In a controlled exposure study, we compared the acute effect of randomized 0.4ppm ozone and air exposures (2 h with intermittent light exercise) in obese (N = 20) (30<BMI<40Kg/m2) vs. non-obese (N = 20) (BMI<25Kg/m2) non-smoking 18тАУ35 year old women. We measured spirometry and bronchial reactivity to inhaled methacholine (3h post-exposure). Inflammation and obesity markers were assessed in the blood (pre, 4h post, and 20h post exposures) and induced-sputum (4h post-exposures and on 24h pre-exposure training day, no exercise): measures of C reactive protein (CRP) (blood only), leptin (blood only), adiponectin, interleukins IL-6, IL-1b, and IL-8, and tumor necrosis factor alpha, and sputum cell differential cell counts. The pre- to post-exposure decrease in forced vital capacity after ozone (adjusted for the change after air exposure) was significantly greater in the obese group (12.5+/-7.5 vs. 8.0+/-5.8%, p<0.05). Post ozone exposure, 6 obese and 6 non-obese subjects responded to methacholine at тЙд 10mg/ml (the maximum dose); the degree of hyperresponsiveness was similar for the two groups. Both BMI groups showed similar and significant ozone-induced increases in sputum neutrophils. Plasma IL-6 was increased by exercise (4 hr post air exposure vs. pre) only in the obese but returned to pre-air exposure levels at 20hr post-exposure. Plasma IL-6 was significantly increased at 4hr post ozone exposure in both groups and returned to pre-exposure levels by 20h post-exposure. These results confirm our previous findings of greater post-ozone spirometric decrements in obese young women. However, acute ozone-induced airway reactivity to methacholine and airway inflammation did not differ by obesity at the exposure and exercise levels used
Impact of recent cyclone lashed along West Bengal, Orissa and northern Andhra Pradesh coasts on the marine fishery sector
Impact of recent cyclone lashed along West Bengal, Orissa
and northern Andhra Pradesh coasts on the marine
fishery secto
Major and minor fisheries harbours of India. 8. Fisherries harbours along the coasts of North Andhra Pradesh, Orissa and West Bengal
The present account gives information about the three major and five minor fisheries harbours along the coasts of north Andhra Pradesh, Orissa and West Benga
Not Available
Not AvailableOn 4-11-'97 a female whale shark, Rhlniodon
typus measuring 6.69 m in total length was landed at
Paradeep, Jagatsinghpur District, OrissaNot Availabl
Not Available
Not AvailableHeavy landings of M.dobsoni, popularly called 'khopra'
in Oriya were noticed at Paradeep centre during the off
season in March and April 1995 in the trawl net. It was
the largest catch ever landed in the last 10 years. It
is also the most important species of prawn in the
commercial fishery of Orissa coast. The unusual
fishery occurred when the prawns migrated to the
shallow waters and were caught by the trawlersNot Availabl
Not Available
Not AvailableA giant grouper, Eplnephalus lanceolatus (Bloch)
(Promicrops lanceolatus) locally called 'Kaibaley' measuring
202 cm in total length was landed at Paradeep on
18-12-'97 by a trawler operated 12 km south of
Paradeep (Fig. 1)Not Availabl