Clinical Features, Cardiovascular Risk Profile, and Therapeutic Trajectories of Patients with Type 2 Diabetes Candidate for Oral Semaglutide Therapy in the Italian Specialist Care

Introduction: This study aimed to address therapeutic inertia in the management of type 2 diabetes (T2D) by investigating the potential of early treatment with oral semaglutide. Methods: A cross-sectional survey was conducted between October 2021 and April 2022 among specialists treating individuals with T2D. A scientific committee designed a data collection form covering demographics, cardiovascular risk, glucose control metrics, ongoing therapies, and physician judgments on treatment appropriateness. Participants completed anonymous patient questionnaires reflecting routine clinical encounters. The preferred therapeutic regimen for each patient was also identified. Results: The analysis was conducted on 4449 patients initiating oral semaglutide. The population had a relatively short disease duration (42%  60% of patients, and more often than sitagliptin or empagliflozin. Conclusion: The study supports the potential of early implementation of oral semaglutide as a strategy to overcome therapeutic inertia and enhance T2D management

[Experimental research on the regenerative capacity of fetal tissue of the extremities injured by teratogenic insult to vascular bases]

[Experimental research on the regenerative capacity of fetal tissue of the extremities injured by teratogenic insult to vascular bases

[Use of a temporo-biparietal skin flap for reconstruction after excision of an epithelioma of the forehead]

[Use of a temporo-biparietal skin flap for reconstruction after excision of an epithelioma of the forehead

[Experimental acroaplasia: study of its etiopathogenetic mechanism]

[Experimental acroaplasia: study of its etiopathogenetic mechanism

[Cross leg flap in successful partial foot amputation for peripheral arteriopathy as an alternative to leg amputation]

[Cross leg flap in successful partial foot amputation for peripheral arteriopathy as an alternative to leg amputation

Variation in acute phlogistic reactions in the skin of rabbit fetuses

There is little in the literature on cutaneous inflammatory reactions in mammal fetuses. The subject now has practical import since advances in medical science allow surgical intervention in premature infants. A study was performed on 45 rabbit fetuses. They were inoculated in the derma of the dorsum with 0.01 ml of a 1% solution of carrageenan, a strong inflammatory drug. Treatment was performed on the nineteenth, twenty-third, and twenty-seventh days of pregnancy. Two rabbits were treated twenty-four hours after birth, and 6 adult rabbits were treated. Histological examination and a count of inflammatory cells were performed on each fetus. The results showed that, during fetal life, the cellular inflammatory reaction is low in the earliest stages but increases gradually during gestation. It is only after birth that there is a great increase, and even then the level remains lower than in adults

Frontal exostose resection during an endoscopic subperiosteal lifting: case report

Ever slowly, plastic surgery has adopted minimally invasive procedures in order to avoid extensive incisions, large scars, and to obtain better results. Endoscopy was introduced into cosmetic surgery of the face in 1992 and it is getting more and more widespread as are its indications, often replacing open surgical approach. Sometimes, a patient seeking a solution to the stigma attached to the aging face may present other problems that are surgically treatable. The authors describe a case of surgical endoscopic resection of a frontal osteoma during endoscopically assisted brow-lift rhytidoplasty

Sporadic distal myopathy

The sporadic distal myopathies are uncommon primary muscle diseases, the pathogenesis of which is still unclear. The inclusion body myositides are inflammatory myopathies, the distal form of which presents some features resembling those of sporadic distal myopathy. A case is reported of a patient showing features of both the first and the second forms

A simple technique to make breast implant capsulectomy easier

A simple technique to make breast implant capsulectomy easie

[Clinico-experimental studies on the use of hyaluronic acid in skin healing processes. Preliminary data]

[Clinico-experimental studies on the use of hyaluronic acid in skin healing processes. Preliminary data