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18th Annual Printing Education Week Celebrated January 14-19A PromiseActivities of RIT Sororities ReviewedAdvertise White Elephants In Spirit "Swap Column"An Open LetterBlock in School ElectsBloomfield-McCluneBook ReviewsBrand New IdeasBurlingame-FrisbyClark Union ClipsDorm DribblesDr. Ellingson Recently Elected Chamber of Commerce PresidentEagles Split; Trotters Take TwoEditor's MailEvening School Adds New CoursesFrat Sweetheart to be Selected at Valentine BallFun with FashionsLost RadianceMen's Bowling League Block A-1946Men's Bowling League-Block A 1945-1946Phi Upsilon Phi Holds Rush Party in Little BarnPrepare Chemistry TestRetailers Extend Vacation; Visit New York CityRetailers Waiting for TrainRings Displayed In Eastman BuildingS.K.D. Makes Selection from Entire SchoolSavage-HurwitzSweetheart BallotThumbnailsValue of College Training ExplainedWanted: Your Gripes, OpinionsWho?Wrestling to be on RIT Sports Panel Next Yea

Climate Variability Drives Plankton Community Composition Changes: the 2010-2011 El Nino to La Nina Transition Around Australia

The strong La Nina of 2010-2011 provided an opportunity to investigate the ecological impacts of El Nino-Southern Oscillation on coastal plankton communities using the nine national reference stations around Australia. Based on remote sensing and across the entire Australian region 2011 (La Nina) was only modestly different from 2010 (El Nino) with the average temperature declining 0.2 percent surface chlorophyll a up 3 percent and modelled primary production down 14 percent. Other changes included a poleward shift in Prochlorococcus and Synechococcus. Along the east coast, there was a reduction in salinity, increase in nutrients, Chlorophytes and Prasinophytes (taxa with chlorophyll b, neoxanthin and prasinoxanthin). The southwest region had a rise in the proportion of 19-hexoyloxyfucoxanthin; possibly coccolithophorids in eddies of the Leeuwin Current and along the sub-tropical front. Pennate diatoms increased, Ceratium spp. decreased and Scrippsiella spp. increased in 2011. Zooplankton biomass declined significantly in 2011. There was a reduction in the abundance of Calocalanus pavo and Temora turbinata and increases in Clausocalanus farrani, Oncaea scottodicarloi and Macrosetella gracilis in 2011. The changes in the plankton community during the strong La Nina of 2011 suggest that this climatic oscillation exacerbates the tropicalization of Australia

Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

Abstract: Precision medicine is part of the logical evolution of contemporary evidence-based medicine that seeks to reduce errors and optimize outcomes when making medical decisions and health recommendations. Diabetes affects hundreds of millions of people worldwide, many of whom will develop life-threatening complications and die prematurely. Precision medicine can potentially address this enormous problem by accounting for heterogeneity in the etiology, clinical presentation and pathogenesis of common forms of diabetes and risks of complications. This second international consensus report on precision diabetes medicine summarizes the findings from a systematic evidence review across the key pillars of precision medicine (prevention, diagnosis, treatment, prognosis) in four recognized forms of diabetes (monogenic, gestational, type 1, type 2). These reviews address key questions about the translation of precision medicine research into practice. Although not complete, owing to the vast literature on this topic, they revealed opportunities for the immediate or near-term clinical implementation of precision diabetes medicine; furthermore, we expose important gaps in knowledge, focusing on the need to obtain new clinically relevant evidence. Gaps include the need for common standards for clinical readiness, including consideration of cost-effectiveness, health equity, predictive accuracy, liability and accessibility. Key milestones are outlined for the broad clinical implementation of precision diabetes medicine. A systematic review of evidence, across the key pillars of prevention, diagnosis, treatment and prognosis, outlines milestones that need to be met to enable the broad clinical implementation of precision medicine in diabetes care