<i>S</i>. <i>pseudintermedius</i>-specific sequences and annotations in strain ED99 that resulted from the sliding-frame analysis.

<p><i>S</i>. <i>pseudintermedius</i>-specific sequences and annotations in strain ED99 that resulted from the sliding-frame analysis.</p

Iteration plot.

<p>Number of frames that met the filter criteria after each iteration. At the 0th iteration all frames of the reference genome are present. The 1st iteration is the comparison to the non-pseudintermedius genomes. All following iterations are comparisons to <i>S</i>. <i>pseudintermedius</i> genomes.</p

Number of staphylococcal genome sequences used for sliding-frame analysis and strains for PCR validation.

<p>Number of staphylococcal genome sequences used for sliding-frame analysis and strains for PCR validation.</p

Additional file 1: Table S1. of Whole genome sequence analysis indicates recent diversification of mammal-associated Campylobacter fetus and implicates a genetic factor associated with H2S production

Table with details of C. fetus SNPs and genes, specific for clades and bovine abortion strains. (XLSX 4167 kb

Additional file 2: Figure S1. of Whole genome sequence analysis indicates recent diversification of mammal-associated Campylobacter fetus and implicates a genetic factor associated with H2S production

Schematic representation of the putative cysteine transporter genes CFF8240_0779 - CFF8240_0781 (white) in strain Cff 8240 with flanking genes rarD and psgA (grey). The start and stop positions of respectively rarD and psgA are shown in italics. Cfv strain 97/608 lacks one complete ORF and contain a remnant of one ORF of the putative cysteine transporter. Shown are the similar deletion sites sequences in the Cfv strains containing the incomplete transporter. (PDF 149 kb

Distribution of <i>Streptococcus suis</i> isolates among patients and pigs in the Netherlands, according to serotype and genotype.

<p>Distribution of <i>Streptococcus suis</i> isolates among patients and pigs in the Netherlands, according to serotype and genotype.</p

Effect of bacteriophage solution on the growth of MRSA V0608892/1.

<p>OD values reflect bacterial concentration in presence of the bacteriophage solution, placebo and no-treated control. The results are presented as the mean OD ± standard deviation of 3 different experiments in duplicate.</p

Eradication of MRSA V0608892/1 from the explants after application of bacteriophage solution and mupirocin.

<p>Data are presented as the mean CFU ± standard deviation of three experiments; time is hours after adhesion.</p

Phylogenetic analyses of concatenated sequences of seven housekeeping gene fragments of <i>Streptococcus suis</i> strains isolated from human patients and pigs in the Netherlands.

<p>The tree was constructed using Neighbor-Joining algorithm in SplitsTree4 using MLST allelic profiles. Distance matrix was obtained from allelic profiles using the SplitsTree program at <a href="http://pubmlst.org/analysis/" target="_blank">http://pubmlst.org/analysis/</a>. ST’s comprising the different clonal complexes are circled. Serotypes are indicated by coloured dots with a diameter corresponding to the number of strains. The horizontal line indicates the scale for genetic distance in arbitrary units.</p

MRSA recovery in the <i>in vivo</i> experiment.

<p>Culture results for nasal samples in the <i>in vivo</i> experiment. Numbers of MRSA are displayed in CFU/swab. The error bars represent standard deviation. Each group consisted of 4 piglets. Group A) piglets that were treated with bacteriophage solution and received mupirocin ointment; B) piglets that received a placebo without bacteriophage and were treated with mupirocin ointment; group C) received a bacteriophage treatment, but no mupirocin and group D) was administered a placebo without bacteriophage and was not treated with mupirocin. △) indicate bacteriophage or placebo treatment; ■) indicate ointment with mupirocin. If a sample was obtained on the same day as treatment took place the sample was taken before treatment was applied.</p