TREATMENT OF ERECTILE DYSFUNCTION IN PATIENTS WITH VIBRATION DISEASE CAUSED BY EXPOSURE OF LOCAL VIBRATION

The article presents the results of complex treatment of erectile dysfunction of 38 patients with vibration disease of II degree. The diagnosis of erectile dysfunction was proved by clinical and instrumental data, besides we carried out survey with determination of international index of erectile dysfunction. Treatment complex included homeopathic remedies, vasodilating ointment for local application and physiotherapeutic procedures. Improvement of the indices of phallography and. the index of erectile dysfunction was registered on the basis of treatments. Total effectiveness of the therapy was 89,9 %

VALUE OF BRAIN STRUCTURE DYSFUNCTION IN PATHOGENESIS AND FORMATION OF CLINICAL PICTURE OF VIBRATION INDUCED DISEASE

The examination of 130 men including neurological examination and. computer electroencephalography with determining of equivalent dipolar sources of pathological activity was performed. Three main groups included employees with a long-term working period exposed by a complex of unfavourable production factors (the local, the whole body vibration, supercooling, physical stress), the patients with occupational polyneuropathy after exposure by a complex of unfavourable factors and. the patients with the vibration-induced diseases due to the local vibration. The study results showed the common signs of the change in bioelectrical brain activity which were found to be characteristic for studied groups compared with clinical symptomatic complex as well as distinguishing features

MUSCULOSKELETAL AND CONNECTIVE TISSUE DISEASES: DISABILITY IN THE IRKUTSK REGION IN 2013–2015

Objective: to study the rates of primary disability due to musculoskeletal and connective tissue diseases (MSCTD) in the Irkutsk Region in 2013–2015 (in relation to age, gender, and urban or rural residence) and its nosological pattern.Material and methods. A continuous method was used to analyze the database on the newly recognized as disabled due to MSCTD in the Irkutsk Region in 2013–2015. The rates were calculated per 10,000 adult population; the pattern was estimated as a percent.Results and discussion. The rates of primary disability due to MSCTD in the Irkutsk Region were higher than those in the Russian Federation as a whole. Its reduction from 10.4 per 10,000 population in 2013 to 10.3 in 2014 and to 5.9 in 2015 was noted in the adults. Osteoarthritis headed the list of the causes of primary disability in the adults (45.5% in 2015) whereas dorsopathies did in the able-bodied (45.9% in 2015, 47.1% in 2014, and 48.2% in 2013). Osteoarthritis ranked first in the retirement-aged (61.5% in 2015, 75.1% in 2014, and 72% in 2013); it occupied the second place in the able-bodied (31.6% in 2015, 36.3% in 2014, and 38.2% in 2013). Rheumatoid arthritis was third among both the able-bodied and the retirement-aged. Higher disability rates were observed in the urban residents over all the years. The women became disabled more frequently than the men. In 2015, the primary disability rates among the men were 5.2, those among the women were 6.4 per 10,000 population; these were 9.2 and 19.4 and 8.4 and 12.1 in 2014 and 2013, respectively. The lower rates of disability due to MSCTD may be attributable to both the greater availability of high-quality and high-tech medical care for patients and the changes in normative documents on disability criteria

Association Between Loss of Dp140 and Cognitive Impairment in Duchenne and Becker Dystrophies

The presence of variable degrees of non progressive cognitive impairment is recognized as a clinical feature of patients with Duchenne and Becker muscular dystrophies (DMD and BMD), but its pathogenesis still remains a matter of debate. A number of findings have proved that rearrangements located in the second part of the dystrophin (DMD) gene seem to be preferentially associated with cognitive impairment. Dp140 is a distal dystrophin isoform, mainly expressed during fetal brain development, whose role for neuropsychological functioning was suggested