1,022 research outputs found
A possible cooling effect in high temperature superconductors
We show that an adiabatic increase of the supercurrent along a superconductor
with lines of nodes of the order parameter on the Fermi surface can result in a
cooling effect. The maximum cooling occurs if the supercurrent increases up to
its critical value. The effect can also be observed in a mixed state of a bulk
sample. An estimate of the energy dissipation shows that substantial cooling
can be performed during a reasonable time even in the microkelvin regime.Comment: 5 pages, to appear in Phys. Rev.
Combined Paramagnetic and Diamagnetic Response of YBCO
It has been predicted that the zero frequency density of states of YBCO in
the superconducting phase can display interesting anisotropy effects when a
magnetic field is applied parallel to the copper-oxide planes, due to the
diamagnetic response of the quasi-particles. In this paper we incorporate
paramagnetism into the theory and show that it lessens the anisotropy and can
even eliminate it altogether. At the same time paramagnetism also changes the
scaling with the square root of the magnetic field first deduced by Volovik
leading to an experimentally testable prediction. We also map out the analytic
structure of the zero frequency density of states as a function of the
diamagnetic and paramagnetic energies. At certain critical magnetic field
values we predict kinks as we vary the magnetic field. However these probably
lie beyond currently accessible field strengths
Repulsive Casimir Force: Sufficient Conditions
In this paper the Casimir energy of two parallel plates made by materials of
different penetration depth and no medium in between is derived. We study the
Casimir force density and derive analytical constraints on the two penetration
depths which are sufficient conditions to ensure repulsion. Compared to other
methods our approach needs no specific model for dielectric or magnetic
material properties and constitutes a complementary analysis.Comment: 11 pages. 3 figures. Misprints corrected in Eq. (4
Immunological Characterization and Neutralizing Ability of Monoclonal Antibodies Directed Against Botulinum Neurotoxin Type H.
BackgroundOnly Clostridium botulinum strain IBCA10-7060 produces the recently described novel botulinum neurotoxin type H (BoNT/H). BoNT/H (N-terminal two-thirds most homologous to BoNT/F and C-terminal one-third most homologous to BoNT/A) requires antitoxin to toxin ratios ≥1190:1 for neutralization by existing antitoxins. Hence, more potent and safer antitoxins against BoNT/H are needed.MethodsWe therefore evaluated our existing monoclonal antibodies (mAbs) to BoNT/A and BoNT/F for BoNT/H binding, created yeast-displayed mutants to select for higher-affinity-binding mAbs by using flow cytometry, and evaluated the mAbs' ability to neutralize BoNT/H in the standard mouse bioassay.ResultsAnti-BoNT/A HCC-binding mAbs RAZ1 and CR2 bound BoNT/H with high affinity. However, only 1 of 6 BoNT/F mAbs (4E17.2A) bound BoNT/H but with an affinity >800-fold lower (equilibrium dissociation binding constant [KD] = 7.56 × 10(-8)M) than its BoNT/F affinity (KD= 9.1 × 10(-11)M), indicating that the N-terminal two-thirds of BoNT/H is immunologically unique. The affinity of 4E17.2A for BoNT/H was increased >500-fold to KD= 1.48 × 10(-10)M (mAb 4E17.2D). A combination of mAbs RAZ1, CR2, and 4E17.2D completely protected mice challenged with 280 mouse median lethal doses of BoNT/H at a mAb dose as low as 5 µg of total antibody.ConclusionsThis 3-mAb combination potently neutralized BoNT/H and represents a potential human antitoxin that could be developed for the prevention and treatment of type H botulism
A General Approach to Casimir Force Problems Based on Local Reflection Amplitudes and Huygen's Principle
In this paper we describe an approach to Casimir Force problems that is
ultimately generalizable to all fields, boundary conditions, and cavity
geometries. This approach utilizes locally defined reflection amplitudes to
express the energy per unit area of any Casimir interaction. To demonstrate
this approach we solve a number of Casimir Force problems including the case of
uniaxial boundary conditions in a parallel-plate cavity.Comment: 9 pages, 5 figures, Equation 18 has been corrected, [v1] contained a
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Dispersion Interactions between Optically Anisotropic Cylinders at all Separations: Retardation Effects for Insulating and Semiconducting Single Wall Carbon Nanotubes
We derive the complete form of the van der Waals dispersion interaction
between two infinitely long anisotropic semiconducting/insulating thin
cylinders at all separations. The derivation is based on the general theory of
dispersion interactions between anisotropic media as formulated in [J. N.
Munday, D. Iannuzzi, Yu. S. Barash and F. Capasso, {\sl Phys. Rev. A} {\bf 71},
042102 (2005)]. This formulation is then used to calculate the dispersion
interactions between a pair of single walled carbon nanotubes at all
separations and all angles. Non-retarded and retarded forms of the interactions
are developed separately. The possibility of repulsive dispersion interactions
and non-monotonic dispersion interactions is discussed within the framework of
the new formulation
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