6,240 research outputs found
Place attachment in deprived neighbourhoods: The impacts of population turnover and social mix
This paper examines the determinants of individual place attachment, focussing in particular on differences between deprived and others neighbourhoods, and on the impacts of population turnover and social mix. It uses a multi-level modelling approach to take account of both individual- and neighbourhood-level determinants. Data are drawn from a large sample government survey, the Citizenship Survey 2005, to which a variety of neighbourhood-level data have been attached. The paper argues that attachment is significantly lower in more deprived neighbourhoods primarily because these areas have weaker social cohesion but that, in other respects, the drivers of attachment are the same. Turnover has modest direct impacts on attachment through its effect on social cohesion. Social mix has very limited impacts on attachment and the effects vary between social groups. In general, higher status or more dominant groups appear less tolerant of social mix
Exoplanet science with the LBTI: instrument status and plans
The Large Binocular Telescope Interferometer (LBTI) is a strategic instrument
of the LBT designed for high-sensitivity, high-contrast, and high-resolution
infrared (1.5-13 m) imaging of nearby planetary systems. To carry out a
wide range of high-spatial resolution observations, it can combine the two
AO-corrected 8.4-m apertures of the LBT in various ways including direct
(non-interferometric) imaging, coronagraphy (APP and AGPM), Fizeau imaging,
non-redundant aperture masking, and nulling interferometry. It also has
broadband, narrowband, and spectrally dispersed capabilities. In this paper, we
review the performance of these modes in terms of exoplanet science
capabilities and describe recent instrumental milestones such as first-light
Fizeau images (with the angular resolution of an equivalent 22.8-m telescope)
and deep interferometric nulling observations.Comment: 12 pages, 6 figures, Proc. SPI
Considerations for Studying Sex as a Biological Variable in Spinal Cord Injury
In response to NIH initiatives to investigate sex as a biological variable in preclinical animal studies, researchers have increased their focus on male and female differences in neurotrauma. Inclusion of both sexes when modeling neurotrauma is leading to the identification of novel areas for therapeutic and scientific exploitation. Here, we review the organizational and activational effects of sex hormones on recovery from injury and how these changes impact the long-term health of spinal cord injury (SCI) patients. When determining how sex affects SCI it remains imperative to expand outcomes beyond locomotor recovery and consider other complications plaguing the quality of life of patients with SCI. Interestingly, the SCI field predominately utilizes female rodents for basic science research which contrasts most other male-biased research fields. We discuss the unique caveats this creates to the translatability of preclinical research in the SCI field. We also review current clinical and preclinical data examining sex as biological variable in SCI. Further, we report how technical considerations such as housing, size, care management, and age, confound the interpretation of sex-specific effects in animal studies of SCI. We have uncovered novel findings regarding how age differentially affects mortality and injury-induced anemia in males and females after SCI, and further identified estrus cycle dysfunction in mice after injury. Emerging concepts underlying sexually dimorphic responses to therapy are also discussed. Through a combination of literature review and primary research observations we present a practical guide for considering and incorporating sex as biological variable in preclinical neurotrauma studies
The Iowa Homemaker vol.3, no.3-4
Table of Contents
The Architectural Design of a Home by Allen Holmes Kimball, page 1
“For a Man’s House Is His Castle” by Alda Wilson, page 2
The Economics of Consumption compiled by John E. Brindley, page 3
Sunfast and Tubfast Materials by Pearl Apland, page 5
On Our Street by Juanita J. Beard, page 6
Who Is Responsible for the Child? by Orange H. Cessna, page 7
Summer Suppers by N. Beth Bailey, page 8
Vacation First Aid by Dr. Mary Sheldon, page 9
Episodes Concerning Evolution of Home Economics by Ruth Elaine Wilson, page 10
Extravagant Economics by Blanche Ingersoll, page 11
Breakfast Bridge by Eleanor Murray, page 12
Veishea Celebrates First Birthday by Helen G. Lamb, page 1
Mechanisms explaining transitions between tonic and phasic firing in neuronal populations as predicted by a low dimensional firing rate model
Several firing patterns experimentally observed in neural populations have
been successfully correlated to animal behavior. Population bursting, hereby
regarded as a period of high firing rate followed by a period of quiescence, is
typically observed in groups of neurons during behavior. Biophysical
membrane-potential models of single cell bursting involve at least three
equations. Extending such models to study the collective behavior of neural
populations involves thousands of equations and can be very expensive
computationally. For this reason, low dimensional population models that
capture biophysical aspects of networks are needed.
\noindent The present paper uses a firing-rate model to study mechanisms that
trigger and stop transitions between tonic and phasic population firing. These
mechanisms are captured through a two-dimensional system, which can potentially
be extended to include interactions between different areas of the nervous
system with a small number of equations. The typical behavior of midbrain
dopaminergic neurons in the rodent is used as an example to illustrate and
interpret our results.
\noindent The model presented here can be used as a building block to study
interactions between networks of neurons. This theoretical approach may help
contextualize and understand the factors involved in regulating burst firing in
populations and how it may modulate distinct aspects of behavior.Comment: 25 pages (including references and appendices); 12 figures uploaded
as separate file
Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eye
Retinal vascular diseases are important causes of vision loss. A detailed evaluation of the vascular abnormalities facilitates diagnosis and treatment in these diseases. Optical coherence tomography (OCT) angiography using the highly efficient split-spectrum amplitude decorrelation angiography algorithm offers an alternative to conventional dye-based retinal angiography. OCT angiography has several advantages, including 3D visualization of retinal and choroidal circulations (including the choriocapillaris) and avoidance of dye injection-related complications. Results from six illustrative cases are reported. In diabetic retinopathy, OCT angiography can detect neovascularization and quantify ischemia. In age-related macular degeneration, choroidal neovascularization can be observed without the obscuration of details caused by dye leakage in conventional angiography. Choriocapillaris dysfunction can be detected in the nonneovascular form of the disease, furthering our understanding of pathogenesis. In choroideremia, OCT's ability to show choroidal and retinal vascular dysfunction separately may be valuable in predicting progression and assessing treatment response. OCT angiography shows promise as a noninvasive alternative to dye-based angiography for highly detailed, in vivo, 3D, quantitative evaluation of retinal vascular abnormalities.National Institutes of Health (U.S.) (Grant R01-EY023285)National Institutes of Health (U.S.) (Grant R01-EY024544)National Institutes of Health (U.S.) (Grant DP3 DK104397)National Institutes of Health (U.S.) (Grant R01-EY11289)National Institutes of Health (U.S.) (Grant K08-EY021186)National Institutes of Health (U.S.) (Grant T32-EY23211)National Institutes of Health (U.S.) (Grant P30-EY010572)Clinical and Translational Science Award Grant UL1TR000128Research to Prevent Blindness, Inc. (United States) (Grant and Career Development Award CD-NMT-0914-0659-OHSU)United States. Air Force Office of Scientific Research (Foundation Fighting Blindness Career Development Award FA9550-10-1-0551)German Research Foundation (Grant DFG-HO-1791/11-1)German Research Foundation (Grant DFG-GSC80-SAOT
Inclusive production of charged hadrons in photon–photon collisions
The inclusive production of charged hadrons in the collisions of quasi-real photons (e+e−→e+e−+Xe+e−→e+e−+X) has been measured using the OPAL detector at LEP. The data were taken at e+e−e+e− centre-of-mass energies from 183 to 209 GeV209 GeV. The differential cross-sections as a function of the transverse momentum and the pseudorapidity of the hadrons are compared to theoretical calculations of up to next-to-leading order (NLO) in the strong coupling constant αsαs. The data are also compared to a measurement by the L3 Collaboration, in which a large deviation from the NLO predictions is observed
Hadronic light-by-light corrections to the muon g-2: the pion-pole contribution
The correction to the muon anomalous magnetic moment from the pion-pole
contribution to the hadronic light-by-light scattering is considered using a
description of the pi0 - gamma* - gamma* transition form factor based on the
large-Nc and short-distance properties of QCD. The resulting two-loop integrals
are treated by first performing the angular integration analytically, using the
method of Gegenbauer polynomials, followed by a numerical evaluation of the
remaining two-dimensional integration over the moduli of the Euclidean loop
momenta. The value obtained, a_{mu}(LbyL;pi0) = +5.8 (1.0) x 10^{-10},
disagrees with other recent calculations. In the case of the vector meson
dominance form factor, the result obtained by following the same procedure
reads a_{mu}(LbyL;pi0)_{VMD} = +5.6 x 10^{-10}, and differs only by its overall
sign from the value obtained by previous authors. Inclusion of the eta and
eta-prime poles gives a total value a_{mu}(LbyL;PS) = +8.3 (1.2) x 10^{-10} for
the three pseudoscalar states. This result substantially reduces the difference
between the experimental value of a_{mu} and its theoretical counterpart in the
standard model.Comment: 27 pages, Latex, 3 figures. v2: version to be published in Phys. Rev.
D, Note added and references updated (don't worry, sign has not changed
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