107 research outputs found
Predictive Task Monitoring for Business Processes
Information sources providing real-time status of physical
objects have drastically increased in recent times. So far, research in
business process monitoring has mainly focused on checking the completion
of tasks. However, the availability of real-time information allows
for a more detailed tracking of individual business tasks. This paper
describes a framework for controlling the safe execution of tasks and signalling
possible misbehaviours at runtime. It outlines a real use case on
smart logistics and the preliminary results of its application.European Union FP7/2007-2013 / 318275 (GET Service
Comprehensive characterization of molecular interactions based on nanomechanics
Molecular interaction is a key concept in our understanding of the biological mechanisms of life. Two physical properties change when one molecular partner binds to another. Firstly, the masses combine and secondly, the structure of at least one binding partner is altered, mechanically transducing the binding into subsequent biological reactions. Here we present a nanomechanical micro-array technique for bio-medical research, which not only monitors the binding of effector molecules to their target but also the subsequent effect on a biological system in vitro. This label-free and real-time method directly and simultaneously tracks mass and nanomechanical changes at the sensor interface using micro-cantilever technology. To prove the concept we measured lipid vesicle (approximately 748*10(6) Da) adsorption on the sensor interface followed by subsequent binding of the bee venom peptide melittin (2840 Da) to the vesicles. The results show the high dynamic range of the instrument and that measuring the mass and structural changes simultaneously allow a comprehensive discussion of molecular interactions
Foot posture influences the electromyographic activity of selected lower limb muscles during gait
Absorbing customer knowledge: how customer involvement enables service design success
Customers are a knowledge resource outside of the firm that can be utilized for new service success by involving them in the design process. However, existing research on the impact of customer involvement (CI) is inconclusive. Knowledge about customersâ needs and on how best to serve these needs (articulated in the service concept) is best obtained from customers themselves. However, codesign runs the risk of losing control of the service concept. This research argues that of the processes of external knowledge, acquisition (via CI), customer knowledge assimilation, and concept transformation form a capability that enables the firm to exploit customer knowledge in the form of a successful new service. Data from a survey of 126 new service projects show that the impact of CI on new service success is fully mediated by customer knowledge assimilation (the deep understanding of customersâ latent needs) and concept transformation (the modification of the service concept due to customer insights). However, its impact is more nuanced. CI exhibits an ââ©â-shaped relationship with transformation, indicating there is a limit to the beneficial effect of CI. Its relationship with assimilation is âUâ shaped, suggesting a problem with cognitive inertia where initial learnings are ignored. Customer knowledge assimilation directly impacts success, while concept transformation only helps success in the presence of resource slack. An evolving new service design is only beneficial if the firm has the flexibility to adapt to change
An online machine learning framework for early detection of product failures in an Industry 4.0 context
Versuche zur Verringerung der Sterblichkeit nach mikrochirurgischen Eingriffen an Amphibienkeimen
Unpacking Charismatic Leadership of Top Management Teams : A Cross-Level Investigation
Do charismatic leadership behaviors of the top management team matter? While such behaviors of the CEO have been found to relate to a variety of positive performance- related outcomes at the firm and individual levels, the leadership literature remains largely silent about the transferability of the charismatic leadership concept to top management teams. According to the upper echelon theory, however, the top management team (TMT) is instrumental in shaping performance outcomes. This makes studies on TMTs and their way of leading organizations particularly relevant. Therefore, this study aims to unpack the effects of TMTsâ charismatic leadership behaviors. Drawing on cross-level data from 274 employees working in 59 organizations, we found that charismatic leadership behaviors of TMTs positively predict their employeesâ affective commitment. Moreover, this cross- level relationship is revealed to be jointly moderated by the employeesâ frequency of interactions with their TMT and their organizationâs ethical climate (i.e., profit versus caring climate). Thus, this study demonstrates the concept of charismatic leadership effectively applied in TMTs, offering important implications for scholars and practitioners
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