HBA1C Levels, Lipid Profile and Thyroid Profile in Patients Admitted with Severe Hypoglycemia in Type 2 Diabetes Mellitus

Objective: We studied the association between HbA1c level, Lipid profile and Thyroid profile in patients admitted with hypoglycemia in type 2 diabetes mellitus. Materials and methods: Patients admitted with severe hypoglycemia (50mg/dl) are included in this observational study from 4 hospitals from January 2013 till January 2015. HBA1C, Lipid profile and Thyroid profile recorded during admission are the points of interest in this study. Demographic and clinical variables were recorded to evaluate the relative risk (RR) of severe hypoglycemia across HbA1c levels. We also studied comorbidities associated with DM. Results: Among 1200 patients enrolled, mean age was 58.6±11.7 years. 83% of patients were above 50 years of age of which 50% were in 50-59 years age group. Mean Glycated hemoglobin was 8.3±2.09. Patients admitted with hypoglycemia constitute 118(9.83%), 64(5.33%), 200 (16.6%), 624(52%) and 194(16.16%) in HbA1c categories 6, 6–6.9, 7–7.9, 8–8.9, and 9% which is statistically significant (P value0.01). Abnormal lipid profile was found in 96.5 %( 1158) of the study population and abnormal Thyroid profile in 11.6%. Conclusions: Hypoglycemia can occur at any level of glycated Hemoglobin but high risk is found with HBA1c of 6% and 8%. Elderly population should not be subjected for stricter control of blood sugars which can do more harm than good. Patients with mean duration of diabetes more than 10 years are at higher risk of recurrent hypoglycemia

Family Unification in Five and Six Dimensions

In family unification models, all three families of quarks and leptons are grouped together into an irreducible representation of a simple gauge group, thus unifying the Standard Model gauge symmetries and a gauged family symmetry. Large orthogonal groups, and the exceptional groups $E_7$ and $E_8$ have been much studied for family unification. The main theoretical difficulty of family unification is the existence of mirror families at the weak scale. It is shown here that family unification without mirror families can be realized in simple five-dimensional and six-dimensional orbifold models similar to those recently proposed for SU(5) and SO(10) grand unification. It is noted that a family unification group that survived to near the weak scale and whose coupling extrapolated to high scales unified with those of the Standard model would be evidence accessible in principle at low energy of the existence of small (Planckian or GUT-scale) extra dimensions.Comment: 13 pages, 2 figures, minor corrections, references adde

Implications of a Massless Neutralino for Neutrino Physics

We consider the phenomenological implications of a soft SUSY breaking term BN at the TeV scale (here B is the U(1)_Y gaugino and N is the right-handed neutrino field). In models with a massless (or nearly massless) neutralino, such a term will give rise through the see-saw mechanism to new contributions to the mass matrix of the light neutrinos. We treat the massless neutralino as an (almost) sterile neutrino and find that its mass depends on the square of the soft SUSY breaking scale, with interesting consequences for neutrino physics. We also show that, although it requires fine-tuning, a massless neutralino in the MSSM or NMSSM is not experimentally excluded. The implications of this scenario for neutrino physics are discussed.Comment: 14 pages, latex, no figure

Seesaw mechanism, baryon asymmetry and neutrinoless double beta decay

A simplified but very instructive analysis of the seesaw mechanism is here performed. Assuming a nearly diagonal Dirac neutrino mass matrix, we study the forms of the Majorana mass matrix of right-handed neutrinos, which reproduce the effective mass matrix of left-handed neutrinos. As a further step, the important effect of a non diagonal Dirac neutrino mass matrix is explored. The corresponding implications for the baryogenesis via leptogenesis and for the neutrinoless double beta decay are reviewed. We propose two distinct models where the baryon asymmetry is enhanced.Comment: 21 pages, RevTex. Revise

Escape from washing out of baryon number in a two-zero-texture general Zee model compatible with the large mixing angle MSW solution

We propose a two-zero-texture general Zee model, compatible with the large mixing angle Mikheyev-Smirnov-Wolfenstein solution. The washing out of the baryon number does not occur in this model for an adequate parameter range. We check the consistency of a model with the constraints coming from flavor changing neutral current processes, the recent cosmic microwave background observation, and the Z-burst scenario.Comment: 22 pages, 2 eps figures, Type set revtex

Leptogenesis in Neutrino Textures with Two Zeros

The leptogenesis is studied in the neutrino textures with two zeros, which reduce the number of independent phases of the CP violation. The phenomenological favored neutrino textures with two zeros are decomposed into the Dirac neutrino mass matrix and the right-handed Majorana one in the see-saw mechanism. Putting the condition to suppress the $\mu \to e\gamma$ decay enough, the texture zeros of the Dirac neutrino mass matrix are fixed in the framework of the MSSM with right-handed neutrinos. These textures have only one CP violatig phase. The magnitude of each entry of the Dirac mass matrix is determined in order to explain the baryon asymmetry of the universe by solving the Boltzman equations. The relation between the leptogenesis and the low energy CP violation is presented in these textures.Comment: Latex file with 20 pages, 6 eps figure

Higgs Scalars in the Minimal Non-minimal Supersymmetric Standard Model

We consider the simplest and most economic version among the proposed non-minimal supersymmetric models, in which the $\mu$-parameter is promoted to a singlet superfield, whose all self-couplings are absent from the renormalizable superpotential. Such a particularly simple form of the renormalizable superpotential may be enforced by discrete $R$-symmetries which are extended to the gravity-induced non-renormalizable operators as well. We show explicitly that within the supergravity-mediated supersymmetry-breaking scenario, the potentially dangerous divergent tadpoles associated with the presence of the gauge singlet first appear at loop levels higher than 5 and therefore do not destabilize the gauge hierarchy. The model provides a natural explanation for the origin of the $\mu$-term, without suffering from the visible axion or the cosmological domain-wall problem. Focusing on the Higgs sector of this minimal non-minimal supersymmetric standard model, we calculate its effective Higgs potential by integrating out the dominant quantum effects due to stop squarks. We then discuss the phenomenological implications of the Higgs scalars predicted by the theory for the present and future high-energy colliders. In particular, we find that our new minimal non-minimal supersymmetric model can naturally accommodate a relatively light charged Higgs boson, with a mass close to the present experimental lower bound.Comment: 63 pages (12 figures), extended versio

Measurement of D0-D0 mixing and search for CP violation in D0→K+K-,π+π- decays with the full Belle data set

We report an improved measurement of D0 – D‾0 mixing and a search for CP violation in D0 decays to CP -even final states K+K− and π+π− . The measurement is based on the final Belle data sample of 976 fb −1 . The results are yCP=(1.11±0.22±0.09)% and AΓ=(−0.03±0.20±0.07)% , where the first uncertainty is statistical and the second is systematic

Track E Implementation Science, Health Systems and Economics

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138412/1/jia218443.pd

Electrical and electronic waste: A global environmental problem

The production of electrical and electronic equipment (EEE) is one of the fastest growing global manufacturing activities. This development has resulted in an increase of waste electric and electronic equipment (WEEE). Rapid economic growth,coupled with urbanization and growing demand for consumer goods, has increased both the consumption of EEE and the production of WEEE, which can be a source of hazardous wastes that pose a risk to the environment and to sustainable economic growth. To address potential environmental problems that could stem from improper management of WEEE, many countries and organizations have drafted national legislation to improve the reuse, recycling and other forms of material recovery from WEEE to reduce the amount and types of materials disposed in landfills. Recycling of waste electric and electronic equipment is important not only to reduce the amount of waste requiring treatment, but also to promote the recovery of valuable materials. EEE is diverse and complex with respect to the materials and components used and waste streams from the manufacturing processes. Characterization of these wastes is of paramount importance for developing a cost-effective and environmentally sound recycling system. This paper offers an overview of electrical and e-waste recycling, including a description of how it is generated and classified, strategies and technologies for recovering materials, and new scientific developments related to these activities. Finally, the e-waste recycling industry in India is also discussed