3,463 research outputs found
Equation of state and transport processes in self--similar spheres
We study the effect of transport processes (diffusion and free--streaming) on
a collapsing spherically symmetric distribution of matter in a self--similar
space--time. A very simple solution shows interesting features when it is
matched with the Vaidya exterior solution. In the mixed case (diffusion and
free--streaming), we find a barotropic equation of state in the stationary
regime. In the diffusion approximation the gravitational potential at the
surface is always constant; if we perturb the stationary state, the system is
very stable, recovering the barotropic equation of state as time progresses. In
the free--streaming case the self--similar evolution is stationary but with a
non--barotropic equation of state.Comment: 9 pages, 2 figure
Activation-Induced Cytidine Deaminase Does Not Impact Murine Meiotic Recombination
Activation-Induced Cytidine Deaminase (AID) was first described as the triggering enzyme of the B-cell-specific reactions that edit the immunoglobulin genes, namely somatic hypermutation, gene conversion and class switch recombination. Over the years, AID was also detected in cells other than lymphocytes, and it has been assigned additional roles in the innate defense against transforming retroviruses, in retrotransposition restriction and in DNA demethylation. Notably, AID expression was found in germline tissues, and in heterologous systems it can induce the double-strand breaks required for the initiation of meiotic recombination and proper gamete formation. However, since AID deficient mice are fully fertile, the molecule is not essential for meiosis. Thus, the remaining question that we addressed here is whether AID influences the frequency of meiotic recombination in mice. We measured the recombination events in the meiosis of male and female mice F1 hybrids of C57BL/6J and BALB/c, in Aicda(+/+) and Aicda(-/-) background using a panel of SNPs that distinguishes C57BL/6J from BALB/c genome across the 19 autosomes. In agreement with the literature, we found that the frequency of recombination in the female germline was higher than in male germline, both in the Aicda(+/+) and the Aicda(-/-) backgrounds. No statistical difference was found in the average recombination events between Aicda(+/+) and Aicda(-/-) animals, either in females or males. In addition, the recombination frequency between SNPs flanking the IgH and Igκ loci was also not different. We conclude that AID has a minor impact, if any, on the overall frequency of meiotic recombination.Marie Curie Reintegration grant: (PIRG03-GA-2008230967), FCT fellowship: (SFRH/BPD/66824/2009)
Empiema pleural por Eikenella corrodens e Porphyromonas asaccharolytica numa doente diabética sob ventilação não invasiva por síndrome de apneia obstrutiva do sono
ResumoA Eikenella corrodens é um microrganismo habitualmente encontrado na mucosa oral, trato gastrointestinal e trato geniturinário de humanos. Os casos de infeção pleuropulmonar por este agente são raros em indivíduos imunocompetentes, sendo a aspiração um fator importante na sua patogenia. Apesar de apresentar geralmente um prognóstico favorável, o reconhecimento desta infeção é essencial dado o perfil de sensibilidades característico. Os autores apresentam um caso de empiema pleural por E. corrodens, em coinfeção com Porphyromonas asaccharolytica, numa doente diabética imunocompetente com síndrome de apneia obstrutiva do sono, discutindo o papel da ventilação não invasiva como fator predisponente da referida infeção.AbstractEikenella corrodens is a normal inhabitant of the human oral cavity and gastrointestinal and genitourinary tracts. Pleuropulmonary infections by this microorganism are uncommon. Pulmonary aspiration is a chief predisposing condition. Although the outcome is usually favorable, its distinctive antibiotic sensitivity pattern makes bacterial identification an important feature in dealing with this infection. The authors report a case of pleural empyema caused by co-infection with Eikenella corrodens and Porphyromonas asaccharolytica, in an immunocompetent diabetic patient with obstructive sleep apnea syndrome, followed by a discussion on the role of noninvasive ventilation in the development of this infection
Nonadiabatic charged spherical evolution in the postquasistatic approximation
We apply the postquasistatic approximation, an iterative method for the
evolution of self-gravitating spheres of matter, to study the evolution of
dissipative and electrically charged distributions in General Relativity. We
evolve nonadiabatic distributions assuming an equation of state that accounts
for the anisotropy induced by the electric charge. Dissipation is described by
streaming out or diffusion approximations. We match the interior solution, in
noncomoving coordinates, with the Vaidya-Reissner-Nordstr\"om exterior
solution. Two models are considered: i) a Schwarzschild-like shell in the
diffusion limit; ii) a Schwarzschild-like interior in the free streaming limit.
These toy models tell us something about the nature of the dissipative and
electrically charged collapse. Diffusion stabilizes the gravitational collapse
producing a spherical shell whose contraction is halted in a short
characteristic hydrodynamic time. The streaming out radiation provides a more
efficient mechanism for emission of energy, redistributing the electric charge
on the whole sphere, while the distribution collapses indefinitely with a
longer hydrodynamic time scale.Comment: 11 pages, 16 Figures. Accepted for publication in Phys Rev
Controlling Physical Systems with Symmetries
Symmetry properties of the evolution equation and the state to be controlled
are shown to determine the basic features of the linear control of unstable
orbits. In particular, the selection of control parameters and their minimal
number are determined by the irreducible representations of the symmetry group
of the linearization about the orbit to be controlled. We use the general
results to demonstrate the effect of symmetry on the control of two sample
physical systems: a coupled map lattice and a particle in a symmetric
potential.Comment: 6 page
Self-similar and charged spheres in the diffusion approximation
We study spherical, charged and self--similar distributions of matter in the
diffusion approximation. We propose a simple, dynamic but physically meaningful
solution. For such a solution we obtain a model in which the distribution
becomes static and changes to dust. The collapse is halted with damped mass
oscillations about the absolute value of the total charge.Comment: 15 pages, 7 figure
Bondian frames to couple matter with radiation
A study is presented for the non linear evolution of a self gravitating
distribution of matter coupled to a massless scalar field. The characteristic
formulation for numerical relativity is used to follow the evolution by a
sequence of light cones open to the future. Bondian frames are used to endow
physical meaning to the matter variables and to the massless scalar field.
Asymptotic approaches to the origin and to infinity are achieved; at the
boundary surface interior and exterior solutions are matched guaranteeing the
Darmois--Lichnerowicz conditions. To show how the scheme works some numerical
models are discussed. We exemplify evolving scalar waves on the following fixed
backgrounds: A) an atmosphere between the boundary surface of an incompressible
mixtured fluid and infinity; B) a polytropic distribution matched to a
Schwarzschild exterior; C) a Schwarzschild- Schwarzschild spacetime. The
conservation of energy, the Newman--Penrose constant preservation and other
expected features are observed.Comment: 20 pages, 6 figures; to appear in General Relativity and Gravitatio
Evaluación económica del manejo de agua y nitrógeno en arroz de riego en el Valle del Cauca
Arroz-Oryza sativ
Reação de genótipos de trigo ao mosaico comum - análise de dados 2010.
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