101 research outputs found
Systematic study of the pp -> pp omega reaction
A systematic study of the production of omega-mesons in
proton-proton-collisions was carried out in a kinematically complete experiment
at three excess energies(epsilon= 92, 128, 173MeV). Both protons were detected
using the large-acceptance COSY-TOF spectrometer at an external beam line at
the Cooler Synchrotron COSY at Forschungszentrum J\"ulich. The total cross
section, angular distributions of both omega-mesons and protons were measured
and presented in various reference frames such as the overall CMS, helicity and
Jackson frame. In addition, the orientation of the omega-spin and invariant
mass spectra were determined. We observe omega-production to take place
dominantly in Ss and Sp final states at epsilon = 92, 128 MeV and,
additionally, in Sd at epsilon= 173 MeV. No obvious indication of resonant
omega-production via N^*-resonances was found, as proton angular distributions
are almost isotropic and invariant mass spectra are compatible with phase space
distributions. A dominant role of ^3P_1 and ^1S_0 initial partial waves for
omega-production was concluded from the orientation of the decay plane of the
omega-meson. Although the Jackson angle distributions in the omega-p-Jackson
frame are anisotropic we argue that this is not an indication of a resonance
but rather a kinematical effect reflecting the anisotropy of the omega angular
distribution. The helicity angle distribution in the omega-p-helicity frame
shows an anisotropy which probably reflects effects of the omega angular
momenta in the final state; this observable may be, in addition to the
orientation of the omega decay plane, the most sensitive one to judge the
validity of theoretical descriptions of the production process.Comment: 17 pages, 16 figures, accepted for publication in EPJ
On the nature of the lowest baryon nonet and decuplet
From recent study of properties of the lowest spin-parity baryons,
and , new pictures for the internal structure of
the lowest baryon octet and decuplet are proposed. While the lowest
baryon octet may have large diquark-diquark-antiquark component, the
lowest baryon decuplet is proposed to have large vector-meson-baryon
components. Evidence for the "missing" members of the new pictures is pointed
out and suggestions are made for detecting these predicted states from
forthcoming experiments.Comment: for Proceedings of NSTAR07 at Bonn, German
Production of Lambda and Sigma^0 hyperons in proton-proton collisions
This paper reports results on simultaneous measurements of the reaction
channels pp -> pK+\Lambda and pp -> pK+\Sigma^0 at excess energies of 204, 239,
and 284 MeV (\Lambda) and 127, 162, and 207 MeV (\Sigma^0). Total and
differential cross sections are given for both reactions. It is concluded from
the measured total cross sections that the high energy limit of the cross
section ratio is almost reached at an excess energy of only about 200 MeV. From
the differential distributions observed in the overall CMS as well as in the
Jackson and helicity frames, a significant contribution of interfering nucleon
resonances to the \Lambda production mechanism is concluded while resonant
\Sigma^0-production seems to be of lesser importance and takes place only
through specific partial waves of the entrance channel. The data also indicate
that kaon exchange plays a minor role in the case of \Lambda- but an important
role for \Sigma^0-production. Thus the peculiar energy dependence of the
\Lambda-to-\Sigma^0 cross section ratio appears in a new light as its
explanation requires more than mere differences between the p\Lambda and the
p\Sigma^0 final state interaction. The data provide a benchmark for theoretical
models already available or yet to come.Comment: 18 pages, 10 figures; accepted by The European Physical Journal A
(EPJ A
Measurement of the Eta Production in Proton Proton Collisions with the COSY Time of Flight Spectrometer
The reaction pp -> pp eta was measured at excess energies of 15 and 41 MeV at
an external target of the Juelich Cooler Synchrotron COSY with the Time of
Flight Spectrometer. About 25000 events were measured for the excess energy of
15 MeV and about 8000 for 41 MeV. Both protons of the process pp eta were
detected with an acceptance of nearly 100% and the eta was reconstructed by the
missing mass technique. For both excess energies the angular distributions are
found to be nearly isotropic. In the invariant mass distributions strong
deviations from the pure phase space distributions are seen.Comment: 15 pages, 14 figures, 4 table
The pK0\Sigma+ final state in proton-proton collisions
This paper reports results from a study of the reaction pp->pK0\Sigma+ at
beam momenta of p_{beam} = 2950, 3059, and 3200 MeV/c (excess energies of
\epsilon= 126, 161, and 206 MeV). Total cross sections were determined for all
energies; a set of differential cross sections (Dalitz plots; invariant mass
spectra of all two-body subsystems; angular distributions of all final state
particles; distributions in helicity and Jackson frames) are presented for
\epsilon= 161 MeV. The total cross sections are proportional to the volume of
available three-body phase-space indicating that the transition matrix element
does not change significantly in this range of excess energies. It is concluded
from the differential data that the reaction proceeds dominantly via the
N(1710)P_{11} and/or N(1720)P_{13} resonance(s); N(1650)S_{11} and
\Delta(1600)P_{33} could also contribute.Comment: 15 pages, 10 figure
Production of mesons in proton-proton collisions
The cross section for the production of mesons in proton-proton
collisions has been measured in a previously unexplored region of incident
energies. Cross sections were extracted at 92 MeV and 173 MeV excess energy,
respectively. The angular distribution of the at =173 MeV is
strongly anisotropic, demonstrating the importance of partial waves beyond pure
s-wave production at this energy.Comment: 12 pages, 4 figures submitted to Physics Letters B v2: figure 1
added, discussion detailing the data analysis, figure 3 (fig. 2 in v1)
modified in line styles and systematic errors displayed on dat
Regulation of the Na,K-ATPase Gamma-Subunit FXYD2 by Runx1 and Ret Signaling in Normal and Injured Non-Peptidergic Nociceptive Sensory Neurons
Dorsal root ganglia (DRGs) contain the cell bodies of sensory neurons which relay nociceptive, thermoceptive, mechanoceptive and proprioceptive information from peripheral tissues toward the central nervous system. These neurons establish constant communication with their targets which insures correct maturation and functioning of the somato-sensory nervous system. Interfering with this two-way communication leads to cellular, electrophysiological and molecular modifications that can eventually cause neuropathic conditions. In this study we reveal that FXYD2, which encodes the gamma-subunit of the Na,K-ATPase reported so far to be mainly expressed in the kidney, is induced in the mouse DRGs at postnatal stages where it is restricted specifically to the TrkB-expressing mechanoceptive and Ret-positive/IB4-binding non-peptidergic nociceptive neurons. In non-peptidergic nociceptors, we show that the transcription factor Runx1 controls FXYD2 expression during the maturation of the somato-sensory system, partly through regulation of the tyrosine kinase receptor Ret. Moreover, Ret signaling maintains FXYD2 expression in adults as demonstrated by the axotomy-induced down-regulation of the gene that can be reverted by in vivo delivery of GDNF family ligands. Altogether, these results establish FXYD2 as a specific marker of defined sensory neuron subtypes and a new target of the Ret signaling pathway during normal maturation of the non-peptidergic nociceptive neurons and after sciatic nerve injury
Influence of N*-resonances on hyperon production in the channel pp->K+ Lambda p at 2.95, 3.20 and 3.30 GeV/c beam momentum
Hyperon production in the threshold region was studied in the reaction pp ->
K+Lp using the time-of-flight spectrometer COSY-TOF. Exclusive data, covering
the full phase-space, were taken at the three different beam momenta of
p_beam=2.95, 3.20 and 3.30 GeV/c, corresponding to excess energies of
epsilon=204, 285 and 316 MeV, respectively. Total cross-sections were deduced
for the three beam momenta to be 23.9+/-0.8 +/-2.0 ub, 28.4+/-1.3 +/-2.2 ub and
35.0+/-1.3 +/-3.0 ub. Differential observables including Dalitz plots were
obtained. The analysis of the Dalitz plots reveals a strong influence of the
N(1650)-resonance at p_beam=2.95 GeV/c, whereas for the higher momenta an
increasing relative contribution of the N(1710)- and/or of the
N(1720)-resonance was observed. In addition, the pL-final-state interaction
turned out to have a significant influence on the Dalitz plot distribution.Comment: accepted for publication at Physics Letters B; some minor text
changes were done; also the scale of the ordinates of figure 9 has been
changed
Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic
Introduction Childhood cancer is a leading cause of death. It is unclear whether the COVID-19 pandemic has impacted childhood cancer mortality. In this study, we aimed to establish all-cause mortality rates for childhood cancers during the COVID-19 pandemic and determine the factors associated with mortality. Methods Prospective cohort study in 109 institutions in 41 countries. Inclusion criteria: children <18 years who were newly diagnosed with or undergoing active treatment for acute lymphoblastic leukaemia, non-Hodgkin's lymphoma, Hodgkin lymphoma, retinoblastoma, Wilms tumour, glioma, osteosarcoma, Ewing sarcoma, rhabdomyosarcoma, medulloblastoma and neuroblastoma. Of 2327 cases, 2118 patients were included in the study. The primary outcome measure was all-cause mortality at 30 days, 90 days and 12 months. Results All-cause mortality was 3.4% (n=71/2084) at 30-day follow-up, 5.7% (n=113/1969) at 90-day follow-up and 13.0% (n=206/1581) at 12-month follow-up. The median time from diagnosis to multidisciplinary team (MDT) plan was longest in low-income countries (7 days, IQR 3-11). Multivariable analysis revealed several factors associated with 12-month mortality, including low-income (OR 6.99 (95% CI 2.49 to 19.68); p<0.001), lower middle income (OR 3.32 (95% CI 1.96 to 5.61); p<0.001) and upper middle income (OR 3.49 (95% CI 2.02 to 6.03); p<0.001) country status and chemotherapy (OR 0.55 (95% CI 0.36 to 0.86); p=0.008) and immunotherapy (OR 0.27 (95% CI 0.08 to 0.91); p=0.035) within 30 days from MDT plan. Multivariable analysis revealed laboratory-confirmed SARS-CoV-2 infection (OR 5.33 (95% CI 1.19 to 23.84); p=0.029) was associated with 30-day mortality. Conclusions Children with cancer are more likely to die within 30 days if infected with SARS-CoV-2. However, timely treatment reduced odds of death. This report provides crucial information to balance the benefits of providing anticancer therapy against the risks of SARS-CoV-2 infection in children with cancer
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