Classification of facial periâ implant soft tissue dehiscence/deficiencies at single implant sites in the esthetic zone

BackgroundThe incidence of a periâ implant soft tissue dehiscence/deficiency (PSTD) is not a rare finding. Despite multiple previous attempts aimed at correcting the PSTDs, a classification of these conditions has not yet been proposed. This lack in the literature may also lead to discrepancies in the reported treatment outcomes and thus misinform the clinician or the readers. The aim of the present article was therefore to present a classification of periâ implant PSTD at a single implant site.MethodsFour classes of PSTDs were discussed based on the position of the gingival margin of the implantâ supported crown in relation to the homologous natural tooth. In addition, the buccoâ lingual position of the implant head was also taken into consideration. Each class was further subdivided based on the height of the anatomical papillae.ResultsSubsequently, for each respective category a surgical approach (including bilaminar techniques, the combined prostheticâ surgical approach or soft tissue augmentation with a submerged healing) was also suggested.ConclusionThis paper provides a new classification system for describing PSTDs at single implant sites, with the appropriate recommended treatment protocol.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/151905/1/jper10351_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/151905/2/jper10351.pd

Toward CP-even Neutrino Beam

The best method of measuring CP violating effect in neutrino oscillation experiments is to construct and use a neutrino beam made of an ideal mixture of $\bar{\nu}_e$ and $\nu_e$ of monochromatic lines. The conceptual design of such a beam is described, together with how to measure the CP-odd quantity. We propose to exploit an accelerated unstable hydrogen-like heavy ion in a storage ring, whose decay has both electron capture and bound beta decay with a comparable fraction.Comment: 6 pages, 2 figures, Published versio

Solving the degeneracy of the lepton-flavor mixing angle theta_atm by the T2KK two detector neutrino oscillation experiment

If the atmospheric neutrino oscillation amplitude, sin^2 2theta_atm is not maximal, there is a two fold ambiguity in the neutrino parameter space: sin^2 theta_atm>0.5 or sin^2 theta_atm<0.5. In this article, we study the impact of this degeneracy, the so-called octant degeneracy, on the T2KK experiment, which is a proposed extension of the T2K (Tokai-to-Kaimoka) neutrino oscillation experiment with an additional water cherenkov detector placed in Korea. We find that the degeneracy between sin^2 theta_atm= 0.40 and 0.60 can be resolved at the 3sigma level for sin^2 2theta_rct>0.12 (0.08) for the optimal combination of a 3.0^circ off-axis beam (OAB) at SK (L=295km) and a 0.5^circ OAB at L=1000km with a far detector of 100kton volume, after 5 years of exposure with 1.0(5.0) time 10^21 POT/year, if the hierarchy is normal. We also study the influence of the octant degeneracy on the capability of T2KK experiment to determine the mass hierarchy and the leptonic CP phase. The capability of rejecting the wrong mass hierarchy grows with increasing sin^2 theta_atm when the hierarchy is normal, whereas it is rather insensitive to sin^2 theta_atm for the inverted hierarchy. We also find that the 1sigma allowed region of the CP phase is not affected significantly even when the octant degeneracy is not resolved. All our results are obtained for the 22.5 kton Super-Kamiokande as a near detector and without an anti-neutrino beam.Comment: 23 pages, 9 figure

Signals for strange quark contributions to the neutrino (antineutrino) scattering in quasi-elastic region

Strange quark contributions to the neutrino (antineutrino) scattering are investigated on the elastic neutrino-nucleon scattering and the neutrino-nucleus scattering for 12C target in the quasi-elastic region on the incident energy of 500 MeV, within the framework of a relativistic single particle model. For the neutrino-nucleus scattering, the effects of final state interaction for the knocked-out nucleon are included by a relativistic optical potential. In the cross sections we found some cancellations of the strange quark contributions between the knocked-out protons and neutrons. Consequently, the asymmetries between the incident neutrino and antineutrino which is the ratio of neutral current to charged current, and the difference between the asymmetries are shown to be able to yield more feasible quantities for the strangeness effects. In order to explicitly display importance of the cancellations, results of the exclusive reaction 16O(\nu, \nu' p) are additionally presented for detecting the strangeness effects.Comment: 14 pages, 8 figures, submitted to Phys. Lett.

Patient-reported outcome measures after periodontal surgery

ObjectivesThe present study aimed to explore the impact of different periodontal surgical treatments on the quality of life and postoperative morbidity.Materials and methodsThe present study is a single-center, prospective, observational cohort trial. One hundred fifty-five patients, referred to the Periodontal Department of Bologna University who needed periodontal surgical treatment, were recruited. The self-reported perception of the postoperative course was assessed using the following anonymous questionnaires: Italian oral health impact profile (I-OHIP-14), visual analog scale (VAS) to evaluate the intensity of the pain, and 5-point Likert scale.ResultsPatients reported a mean OHIP-14 total score of 9.87 +/- 8.5 (range 0-42), significantly influenced by the female sex, flap extension, and periodontal dressing. A mean VAS score of 2.96 +/- 2.39 (range 0-9) was calculated, and was found to be influenced by the presence of vertical releasing incisions and palatal flap extension. Of the 155 subjects, 40 (25.8%) patients reported bleeding as a post-surgical complication, 96 (61.9%) swelling, 105 (67.7%) eating discomfort, and 44 (28.4%) reported speech discomfort.ConclusionsWithin the limitations of the nature of the present study, periodontal surgical procedures have a low impact on patients' quality of life evaluated through the OHIP-14 and VAS pain questionnaires.Clinical relevancePeriodontal surgical procedures are safe procedures, with a limited duration of postoperative discomfort as well as the incidence of complications

Neutrino tomography - Learning about the Earth's interior using the propagation of neutrinos

Because the propagation of neutrinos is affected by the presence of Earth matter, it opens new possibilities to probe the Earth's interior. Different approaches range from techniques based upon the interaction of high energy (above TeV) neutrinos with Earth matter, to methods using the MSW effect on the neutrino oscillations of low energy (MeV to GeV) neutrinos. In principle, neutrinos from many different sources (sun, atmosphere, supernovae, beams etc.) can be used. In this talk, we summarize and compare different approaches with an emphasis on more recent developments. In addition, we point out other geophysical aspects relevant for neutrino oscillations.Comment: 22 pages, 9 figures. Proceedings of ``Neutrino sciences 2005: Neutrino geophysics'', December 14-16, 2005, Honolulu, USA. Minor changes, some references added. Final version to appear in Earth, Moon, and Planet

The acceleration and storage of radioactive ions for a neutrino factory

The term beta-beam has been coined for the production of a pure beam of electron neutrinos or their antiparticles through the decay of radioactive ions circulating in a storage ring. This concept requires radioactive ions to be accelerated to a Lorentz gamma of 150 for 6He and 60 for 18Ne. The neutrino source itself consists of a storage ring for this energy range, with long straight sections in line with the experiment(s). Such a decay ring does not exist at CERN today, nor does a high-intensity proton source for the production of the radioactive ions. Nevertheless, the existing CERN accelerator infrastructure could be used as this would still represent an important saving for a beta-beam facility. This paper outlines the first study, while some of the more speculative ideas will need further investigations.Comment: Accepted for publication in proceedings of Nufact02, London, 200

Is a soft tissue graft harvested from the maxillary tuberosity the approach of choice in an isolated site?

Soft tissue augmentation procedures are becoming more popular these days. Different soft tissue graft harvesting approaches have been proposed. Nonetheless, the location of the donor site (whether anterior-, lateral-, superficial-, deep-palate or the maxillary tuberosity) can affect the graft shape and its composition. Soft tissue grafts from the maxillary tuberosity are rich in connective tissue fibers, with minimal presence of fatty or glandular components. Clinical, histological, and molecular evidence shows that a soft tissue graft obtained from the maxillary tuberosity has unique properties. In addition, harvesting from this area presents minimal risk for intra- or postoperative complications, leading to reduced patient morbidity. The aim of this commentary is to discuss the advantages and disadvantages of harvesting a soft tissue graft from the tuberosity and to compare it with the traditional palatal graft, while highlighting functional, esthetic, and patient-related outcomes.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/151301/1/jper10300_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/151301/2/jper10300.pd

A Beta Beam complex based on the machine upgrades for the LHC

The Beta Beam CERN design is based on the present LHC injection complex and its physics reach is mainly limited by the maximum rigidity of the SPS. In fact, some of the scenarios for the machine upgrades of the LHC, particularly the construction of a fast cycling 1 TeV injector (``Super-SPS''), are very synergic with the construction of a higher $\gamma$ Beta Beam. At the energies that can be reached by this machine, we demonstrate that dense calorimeters can already be used for the detection of $\nu$ at the far location. Even at moderate masses (40 kton) as the ones imposed by the use of existing underground halls at Gran Sasso, the CP reach is very large for any value of $\theta_{13}$ that would provide evidence of $\nu_e$ appearance at T2K or NO$\nu$A ($\theta_{13}\geq 3^\circ$). Exploitation of matter effects at the CERN to Gran Sasso distance provides sensitivity to the neutrino mass hierarchy in significant areas of the $\theta_{13}-\delta$ plane

Identification of antisense long noncoding RNAs that function as SINEUPs in human cells

Mammalian genomes encode numerous natural antisense long noncoding RNAs (lncRNAs) that regulate gene expression. Recently, an antisense lncRNA to mouse Ubiquitin carboxyl-terminal hydrolase L1 (Uchl1) was reported to increase UCHL1 protein synthesis, representing a new functional class of lncRNAs, designated as SINEUPs, for SINE element-containing translation UP-regulators. Here, we show that an antisense lncRNA to the human protein phosphatase 1 regulatory subunit 12A (PPP1R12A), named as R12A-AS1, which overlaps with the 5' UTR and first coding exon of the PPP1R12A mRNA, functions as a SINEUP, increasing PPP1R12A protein translation in human cells. The SINEUP activity depends on the aforementioned sense-antisense interaction and a free right Alu monomer repeat element at the 3' end of R12A-AS1. In addition, we identify another human antisense lncRNA with SINEUP activity. Our results demonstrate for the first time that human natural antisense lncRNAs can up-regulate protein translation, suggesting that endogenous SINEUPs may be widespread and present in many mammalian species