882 research outputs found
1863-10-10 Lt. Colonel Farnham writes General Hodsdon regarding annual returns
https://digitalmaine.com/cw_me_16th_regiment_corr/1268/thumbnail.jp
1863-08-21 Lt. Colonel Augustus B. Farnham to Adjutant General Hodsdon
https://digitalmaine.com/cw_me_16th_regiment_corr/1000/thumbnail.jp
1861-11-17 Captain Augustus B. Farnham writes to Adjutant General Hodsdon informing him of the death of Augustus Hutchins
https://digitalmaine.com/cw_me_2nd_regiment_corr/1198/thumbnail.jp
1863-07-31 Regimental return after Battle of Gettysburg
https://digitalmaine.com/cw_me_16th_regiment_corr/1003/thumbnail.jp
Comet Machholz (C/2004 Q2): morphological structures in the inner coma and rotation parameters
Extensive observations of comet C/2004 Q2 (Machholz) were carried out between
August 2004 and May 2005. The images obtained were used to investigate the
comet's inner coma features at resolutions between 350 and 1500 km/pixel. A
photometric analysis of the dust outflowing from the comet's nucleus and the
study of the motion of the morphological structures in the inner coma indicated
that the rotation period of the nucleus was most likely around 0.74 days. A
thorough investigation of the inner coma morphology allowed us to observe two
main active sources on the comet's nucleus, at a latitude of +85{\deg} \pm
5{\deg} and +45{\deg} \pm 5{\deg}, respectively. Further sources have been
observed, but their activity ran out quite rapidly over time; the most relevant
was at latcom. = 25{\deg} \pm 5{\deg}. Graphic simulations of the geometrical
conditions of observation of the inner coma were compared with the images and
used to determine a pole orientation at RA=95{\deg} \pm 5{\deg}, Dec=+35{\deg}
\pm 5{\deg}. The comet's spin axis was lying nearly on the plane of the sky
during the first decade of December 2004.Comment: 29 pages, 8 figures, 3 table
The Claims Culture: A Taxonomy of Industry Attitudes
This paper presents an analysis of a familiar aspect of construction industry culture that we have dubbed 'the claims culture'. This is a culture of contract administration that lays a strong emphasis on the planning and management of claims. The principal elements of the analysis are two sets of distinctions. The first comprises economic and occupational orders, referring to two kinds of control that are exercised over the construction process; predicated respectively on economic ownership and occupational competence. The second refers to contrasting attitudes towards relationships and problem solving within these orders: respectively 'distributive' and 'integrative'. The concepts of economic and occupational order entail further sub-categories. The various attitudes associated with these categories and sub-categories are described. They are assessed as to their consequences for change initiatives in the industry
1863-07-03 List of the Killed, Wounded, & Missing in the 16th Maine Regiment Infantry Volunteers at the Battle of Gettysburg
https://digitalmaine.com/cw_me_16th_regiment_corr/1001/thumbnail.jp
Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines.
BACKGROUND: The cell-surface attachment protein (Env) of the HERV-K(HML-2) lineage of endogenous retroviruses is a potentially attractive tumour-associated antigen for anti-cancer immunotherapy. The human genome contains around 100 integrated copies (called proviruses or loci) of the HERV-K(HML-2) virus and we argue that it is important for therapy development to know which and how many of these contribute to protein expression, and how this varies across tissues. We measured relative provirus expression in HERV-K(HML-2), using enriched RNA-Seq analysis with both short- and long-read sequencing, in three Mantle Cell Lymphoma cell lines (JVM2, Granta519 and REC1). We also confirmed expression of the Env protein in two of our cell lines using Western blotting, and analysed provirus expression data from all other relevant published studies. RESULTS: Firstly, in both our and other reanalysed studies, approximately 10% of the transcripts mapping to HERV-K(HML-2) came from Env-encoding proviruses. Secondly, in one cell line the majority of the protein expression appears to come from one provirus (12q14.1). Thirdly, we find a strong tissue-specific pattern of provirus expression. CONCLUSIONS: A possible dependency of Env expression on a single provirus, combined with the earlier observation that this provirus is not present in all individuals and a general pattern of tissue-specific expression among proviruses, has serious implications for future HERV-K(HML-2)-targeted immunotherapy. Further research into HERV-K(HML-2) as a possible tumour-associated antigen in blood cancers requires a more targeted, proteome-based, screening protocol that will consider these polymorphisms within HERV-K(HML-2). We include a plan (and necessary alignments) for such work
The First 1 1/2 Years of TOTEM Roman Pot Operation at LHC
Since the LHC running season 2010, the TOTEM Roman Pots (RPs) are fully
operational and serve for collecting elastic and diffractive proton-proton
scattering data. Like for other moveable devices approaching the high intensity
LHC beams, a reliable and precise control of the RP position is critical to
machine protection. After a review of the RP movement control and position
interlock system, the crucial task of alignment will be discussed.Comment: 3 pages, 6 figures; 2nd International Particle Accelerator Conference
(IPAC 2011), San Sebastian, Spain; contribution MOPO01
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