638 research outputs found

    L2 Vocabulary Acquisition: Investigating the Key to Lexical Comprehension

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    L2 researchers have debated the significance of the lexicon in addition to the relevance of acquiring syntax, in the learning of an L2. (Huckin et.al, 1993; Haastrup, 1991) and other researchers in the field of SLA recognize the fact that learners' knowledge of words from context assists them in the comprehension of unfamiliar words that they encounter in their reading materials. Academic reading materials tend to be cognitively demanding and often require language in which contextual cues for meaning are reduced. Research in lexical acquisition has gained significant grounds lately, comparable to that of studies in the acquisition of syntax, which have played a prominent role in SLA.This study investigates the strategies employed by L2 learners towards their lexical development. It specifically addresses questions such as:Do learners acquire vocabulary through guessing from meaning?Do they retain the new words learnt in phrases?Do they employ the use of dictionaries?How significant do they consider the acquiring of vocabulary in their L2 learning?What are the strategies employed by the learners to gain a broader vocabulary?Tests that attempt to measure the learners' vocabulary competence were administered to 70 students from the Foundation Program at Curtin University of Technology, Sarawak Campus. In addition, questionnaires elicited numerous responses in their approach to lexical acquisition. This study provides a framework for a discussion of the various aspects of vocabulary acquisition among L2 learners. The findings from the analyses of the tests designate that vocabulary learning occurs through extensive reading and that learners with prior vocabulary knowledge often used topic knowledge and clues to understand unknown words from context, among other facts

    Soil-transmitted helminthiasis in Laos: A community-wide cross-sectional study of humans and dogs in a mass drug administration environment

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    We conducted a community cross-sectional survey of soil-transmitted helminthiasis in humans and dogs in four provinces in northern Laos. We collected and tested human and dog fecal samples and analyzed results against sociodemographic data. The prevalence of Ascaris lumbricoides, Trichuris trichiura, hookworm, and Strongyloides stercoralis was 26.1% (95% confidence interval [CI,1 = 23.7-28.4%), 41.5% (95% CI = 38.8-44.1%), 46.3% (95% CI = 43.3-49.0%), and 8.9% (95% CI = 7.4-10.4%), respectively. We observed strong heterogeneity for helminthiasis by ethnicity, province, and wealth status, which coincided with a risk profile demonstrating that Mon-Khmer persons and the poorest households are highly vulnerable. Necator americanus was the dominant hookworm species infecting humans and Ancylostoma ceylanicum was the only Ancylastoma species detected. Hookworm prevalence in village dogs was 94%, and the dominant species was A. ceylanicum. Necator americanus was also detected in dogs. It appears that dogs have a role in human hookworm transmission and warrant further investigation

    Effect of Training/Competition Load and Scheduling on Sleep Characteristics in Professional Rugby League Athletes.

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    AbstractConlan, G, McLean, B, Kemp, J, and Duffield, R. Effect of training/competition load and scheduling on sleep characteristics in professional rugby league athletes. J Strength Cond Res XX(X): 000-000, 2021-This study examined the effect of training/competition load, scheduling, and associated factors on sleep behavior in professional rugby league athletes. Sleep characteristics were assessed in 26 professional rugby league athletes using wrist-mounted actigraphy and nightly sleep diaries. Sleep actigraphy assessed the time into and out of bed, the duration in bed, sleep duration, efficiency, latency, wake after sleep onset, number of awakenings, and the awakening length. Sleep was measured during 3 different weeks: (a) preseason low training load (TL) (2,356 ± 322 AU), (b) preseason high TL (3,542 ± 445 AU), and (c) in-season match week (1,526 ± 409 AU). The influences of internal TL (session rating of perceived exertion load), training schedule, age, and training location on sleep behavior were analyzed. Repeated-measures 2-way analysis of variance and effect size analyses (d) compared sleep variables between training weeks. The mean weekly sleep duration was significantly lower during high TL week (5 hours 53minutes ± 14 min/night; p = 0.015, d = 0.59) compared with the low TL (6 hours 25minutes ± 8 min·night-1) or match weeks (6 hours 26minutes ± 10 min·night-1; p = 0.02, d = 2.04). Reduced sleep duration in the high TL week occurred alongside earlier out-of-bed times compared with the low TL (p = 0.003, d = 1.46) and match weeks (p = 0.001, d = 5.99). Regardless, the lowest sleep duration was on match night (p = 0.0001, d = 1.22). Earlier training start times resulted in earlier wake times (p = 0.003, d = 4.84), shorter in-bed durations (p = 0.0001, d = 0.62), and shorter sleep durations (p = 0.002, d = 0.32). Younger athletes slept for longer durations (p = 0.029, d = 1.70) and perceived their sleep quality to be superior (p = 0.006, d = 14.94) compared with older athletes. Sleep attained by rugby league athletes is influenced by training and competition schedules, with early training start times and late-night matches being primary drivers of sleep behavior. Coaching staff should have awareness surrounding the implications of training and playing schedules on athlete sleeping patterns

    Potential of Van de Ven’s (2007) concept of engaged scholarship to enhance the sustainability and appropriateness of management consultancy and university knowledge exchange projects recommendations to challenge the widespread hype of newness (Smil, 2022)

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    This paper will outline some emerging thoughts on the potential applicability of Van de Ven’s Engaged Scholarship concept in consultancy and knowledge exchange projects. To structure this paper the questions posed at an event titled “Putting Engaged Scholarship to Work: Projects, Partners and Progress” hosted by Ram (2019 cited by Kapasi) at Aston University will be summarised. The original definition of Engaged Scholarship offered by Van de Ven (2007) is that it is “a participative form of research for obtaining the advice and perspectives of key stakeholders (researchers, users, clients, sponsors, and practitioners) to understand a complex social problem” The commentary will be illustrated by some wider evidence drawn from industry analysis, professional bodies and academic research on Organisational Transformation and Digital Transformation Projects. These sources are frequently conducted independently where concentration on individual technical, and often siloed, aspects of consultancy and knowledge exchange project recommendations do not address the necessary breadth of understanding to improve the sustainability of such projects and therefore challenge the hype (Smil, 2022) that is associated with complex and expensive societal challenge of the typically high failure rates of Organisational Transformation and Digital Transformation investments. It is proposed by Neal et al (2023) that role frequently referred to as “Brokers, intermediaries, and boundary spanners (BIBS)” can offer a “… bridge (to) research and policy or practice and can elevate the role of evidence in decision making” (op cit)

    Norovirus transmission dynamics: a modelling review.

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    Norovirus is one of the leading causes of viral gastroenteritis worldwide and responsible for substantial morbidity, mortality and healthcare costs. To further understanding of the epidemiology and control of norovirus, there has been much recent interest in describing the transmission dynamics of norovirus through mathematical models. In this study, we review the current modelling approaches for norovirus transmission. We examine the data and methods used to estimate these models that vary structurally and parametrically between different epidemiological contexts. Many of the existing studies at population level have focused on the same case notification dataset, whereas models from outbreak settings are highly specific and difficult to generalise. In this review, we explore the consistency in the description of norovirus transmission dynamics and the robustness of parameter estimates between studies. In particular, we find that there is considerable variability in estimates of key parameters such as the basic reproduction number, which may mean that the effort required to control norovirus at the population level may currently be underestimated.Takeda Pharmaceutical

    The dynamics of measles in sub-Saharan Africa.

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    Although vaccination has almost eliminated measles in parts of the world, the disease remains a major killer in some high birth rate countries of the Sahel. On the basis of measles dynamics for industrialized countries, high birth rate regions should experience regular annual epidemics. Here, however, we show that measles epidemics in Niger are highly episodic, particularly in the capital Niamey. Models demonstrate that this variability arises from powerful seasonality in transmission-generating high amplitude epidemics-within the chaotic domain of deterministic dynamics. In practice, this leads to frequent stochastic fadeouts, interspersed with irregular, large epidemics. A metapopulation model illustrates how increased vaccine coverage, but still below the local elimination threshold, could lead to increasingly variable major outbreaks in highly seasonally forced contexts. Such erratic dynamics emphasize the importance both of control strategies that address build-up of susceptible individuals and efforts to mitigate the impact of large outbreaks when they occur

    Prevalence of endemic pig-associated zoonoses in Southeast Asia: A review of findings from the Lao people's Democratic Republic

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    The increasing intensification of pork production in southeast Asia necessitates an urgent requirement to better understand the dual impact of pig-associated zoonotic disease on both pig production and human health in the region. Sharing porous borders with five countries and representing many regional ethnicities and agricultural practices, the Lao People's Democratic Republic (Lao PDR) appears well placed to gauge the levels of pig-associated zoonoses circulating in the wider region. Despite this, little is known about the true impact of zoonotic pathogens such as leptospirosis, Trichinella, hepatitis E virus (HEV), Japanese encephalitis (JE), and Taenia solium on human health and livestock production in the country. A comprehensive review of the published prevalences of these five pig-associated zoonoses in Lao PDR has demonstrated that although suspicion remains high of their existence in pig reservoirs across the country, epidemiological data are scarce; only 31 epidemiological studies have been undertaken on these diseases in the past 25 years. A greater understanding of the zoonoses prevalence and subsequent risks associated with pork production in the southeast Asian region could help focus public health and food safety interventions at key points along the value chain, benefiting both livestock producers and the broader animal and human health systems in the region

    Bone Morphogenetic Protein-9 Is a Potent Chondrogenic and Morphogenic Factor for Articular Cartilage Chondroprogenitors

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    Articular cartilage contains a subpopulation of tissue-specific progenitors that are an ideal cell type for cell therapies and generating neo-cartilage for tissue engineering applications. However, it is unclear whether the standard chondrogenic medium employing transforming growth factor-β (TGFβ) isoforms is optimal to differentiate these cells. We therefore used pellet culture to screen progenitors from immature bovine articular cartilage with a number of chondrogenic factors and discovered that bone morphogenetic factor-9 (BMP9) precociously induces their differentiation. This difference was apparent with toluidine blue staining and confirmed by biochemical and transcriptional analyses with BMP9 treated progenitors exhibiting 11-fold and 5-fold greater aggrecan and collagen type II gene expression than TGFβ1 treated progenitors. Quantitative gene expression analysis over 14 days highlighted the rapid and phased nature of BMP9 induced chondrogenesis with sequential activation of aggrecan then collagen type II, and negligible collagen type X gene expression. The extracellular matrix of TGFβ1treated progenitors analysed using atomic force microscopy was fibrillar and stiff whist BMP9-induced matrix of cells more compliant and correspondingly less fibrillar. Polarised light microscopy revealed an annular pattern of collagen fibril deposition typified by TGFβ1 treated pellets, whereas BMP9 treated pellets displayed a birefringence pattern that was more anisotropic. Remarkably, differentiated immature chondrocytes incubated as high-density cultures in vitro with BMP9 generated a pronounced anisotropic organisation of collagen fibrils indistinguishable from mature adult articular cartilage, with cells in deeper zones arranged in columnar fashion. This contrasted with cells grown with TGFβ1 where a concentric pattern of collagen fibrils was visualised within tissue pellets. In summary, BMP9 is a potent chondrogenic factor for articular cartilage progenitors and is also capable of inducing morphogenesis of adult-like cartilage, a highly desirable attribute for in vitro tissue-engineered cartilage
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