A novel approach for the effective prediction of cardiovascular disease using applied artificial intelligence techniques

Aims: The objective of this research is to develop an effective cardiovascular disease prediction framework using machine learning techniques and to achieve high accuracy for the prediction of cardiovascular disease. Methods: In this paper, we have utilized machine learning algorithms to predict cardiovascular disease on the basis of symptoms such as chest pain, age and blood pressure. This study incorporated five distinct datasets: Heart UCI, Stroke, Heart Statlog, Framingham and Coronary Heart dataset obtained from online sources. For the implementation of the framework, RapidMiner tool was used. The three‐step approach includes pre‐processing of the dataset, applying feature selection method on pre‐processed dataset and then applying classification methods for prediction of results. We addressed missing values by replacing them with mean, and class imbalance was handled using sample bootstrapping. Various machine learning classifiers were applied out of which random forest with AdaBoost dataset using 10‐fold cross‐validation provided the high accuracy. Results: The proposed model provides the highest accuracy of 99.48% on Heart Statlog, 93.90% on Heart UCI, 96.25% on Stroke dataset, 86% on Framingham dataset and 78.36% on Coronary heart disease dataset, respectively. Conclusions: In conclusion, the results of the study have shown remarkable potential of the proposed framework. By handling imbalance and missing values, a significantly accurate framework has been established that could effectively contribute to the prediction of cardiovascular disease at early stages

A Machine Learning-Based Framework for Accurate and Early Diagnosis of Liver Diseases: A Comprehensive Study on Feature Selection, Data Imbalance, and Algorithmic Performance

The liver is the largest organ of the human body with more than 500 vital functions. In recent decades, a large number of liver patients have been reported with diseases such as cirrhosis, fibrosis, or other liver disorders. There is a need for effective, early, and accurate identification of individuals suffering from such disease so that the person may recover before the disease spreads and becomes fatal. For this, applications of machine learning are playing a significant role. Despite the advancements, existing systems remain inconsistent in performance due to limited feature selection and data imbalance. In this article, we reviewed 58 articles extracted from 5 different electronic repositories published from January 2015 to 2023. After a systematic and protocol-based review, we answered 6 research questions about machine learning algorithms. The identification of effective feature selection techniques, data imbalance management techniques, accurate machine learning algorithms, a list of available data sets with their URLs and characteristics, and feature importance based on usage has been identified for diagnosing liver disease. The reason to select this research question is, in any machine learning framework, the role of dimensionality reduction, data imbalance management, machine learning algorithm with its accuracy, and data itself is very significant. Based on the conducted review, a framework, machine learning-based liver disease diagnosis (MaLLiDD), has been proposed and validated using three datasets. The proposed framework classified liver disorders with 99.56%, 76.56%, and 76.11% accuracy. In conclusion, this article addressed six research questions by identifying effective feature selection techniques, data imbalance management techniques, algorithms, datasets, and feature importance based on usage. It also demonstrated a high accuracy with the framework for early diagnosis, marking a significant advancement

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year. Conclusion As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population.The aim of this study was to inform vaccination prioritization by modelling the impact of vaccination on elective inpatient surgery. The study found that patients aged at least 70 years needing elective surgery should be prioritized alongside other high-risk groups during early vaccination programmes. Once vaccines are rolled out to younger populations, prioritizing surgical patients is advantageous