Fyysisen aktiivisuuden yhteys lannenikaman kokoon 20- ja 30-vuotiailla aikuisilla

Tiivistelmä. Nikaman pieni koko on tärkeä nikamamurtumien riskitekijä. Tutkimme, vaikuttavatko fyysinen aktiivisuus ja impaktilajeihin osallistuminen nikaman poikkipinta-alan kasvunopeuteen nuorilla aikuisilla. Tutkimusväestönämme käytimme Pohjois-Suomen syntymäkohortin 1986 osakohorttia (n = 375). Tutkimusväestömme kävi kliinisissä tutkimuksissa 15–19-vuotiaina ja täyttivät samalla kyselyn liittyen heidän elintapoihinsa ja terveyteensä. Tutkimuksessamme käytetyt MRI-kuvat otettiin 20- ja 30-vuotiaina. Käytimme yleistä arviointiyhtälöä (generalized estimating equation, GEE) mallintaaksemme yhteyttä muuttujiemme välillä. Kun tarkastelimme yhteyttä nikaman poikkipinta-alan, liikunnallisen aktiivisuuden ja korkean impaktin lajien välillä, emme löytäneet yhtään tilastollisesti merkitsevää tulosta. Aikainteraktion huomioiminen ei myöskään tuottanut yhtään tilastollisesti merkitsevää tulosta. Johtopäätöksenä liikunnan harjoittaminen ei auta kasvattamaan nikaman mittoja tai pinta-alaa, eikä siis sitä kautta ehkäise nikamamurtumia

Baseline anthropometric indices predict change in vertebral size in early adulthood:a 10-year follow-up MRI study

Abstract The vertebral cross-sectional area (CSA) has an independent effect on vertebral strength. Recent evidence has shown that vertebral dimensions significantly increase in the third decade of life, and that lifestyle factors such as body size and composition are clearly associated with vertebral CSA. This study aimed to test the hypothesis that general anthropometric traits (stature, total body mass, lean body mass, fat mass, body mass index, waist circumference), each objectively measured at baseline, predict the change in vertebral CSA over the subsequent decade. A representative sample of young Northern Finnish adults was used (n = 371) with repeated magnetic resonance imaging (MRI) scans from ~20 and ~30 years (baseline and follow-up, respectively). Vertebral CSA was measured from the MRI scans with high reliability and low measurement error. The statistical analysis was performed using linear regression models adjusted for sex and exact length of MRI interval. According to the regression models, in descending order of effect size, lean body mass (standardized beta coefficient 0.243 [95% confidence interval 0.065—0.420]), total body mass (0.158 [0.043—0.273]), body mass index (0.125 [0.026—0.224]), waist circumference (0.119 [0.010—0.228]), and fat mass (0.104 [0.004—0.205]) were positively and significantly associated with CSA gain over the follow-up, whereas stature (0.079 [−0.066—0.224]) was not associated with CSA change. The results of this study suggest that anthropometric indices may be used for estimating subsequent change in vertebral size. In particular, greater lean body mass seems to be beneficial for vertebral size and thus potentially also for vertebral strength. Future studies should aim to replicate these associations in a dataset with longitudinal anthropometric trajectories and identify the potential common factors that influence both anthropometric traits and vertebral CSA gain

Changes in vertebral dimensions in early adulthood:a 10-year follow-up MRI-study

Abstract Previous studies have shown that vertebral height increases until the early twenties, but very few studies have been conducted on other vertebral dimensions. Growth in vertebral size is believed to take place in elderly age but not in early adulthood. In this study, we wanted to clarify the potential changes in the dimensions of the lumbar vertebrae during early adulthood. We used the Northern Finland Birth Cohort 1986 as our study material, with a final sample size of 375 individuals. We performed lumbar magnetic resonance imaging (MRI) when the participants were 20 and 30 years of age (baseline and follow-up, respectively). We recorded the width, depth, height, and cross-sectional area (CSA) of the fourth lumbar vertebra (L4) using the MRI scans. We used generalized estimating equation (GEE) models to analyse the data. Men had 7.6%–26.5% larger vertebral dimensions than women at both baseline and follow-up. The GEE models demonstrated that all the studied dimensions increased during the follow-up period among both sexes (p < 0.001). Men had a higher growth rate in vertebral depth and CSA than women (p < 0.001). Among women, small vertebral width (p = 0.001), depth (p = 0.05) and height (p = 0.02) at baseline were associated with a higher vertebral growth rate during the follow-up than among those with large dimensions at baseline. Among men, small baseline width was associated with higher vertebral growth rate (p = 0.001). Our results clearly indicate that vertebral dimensions increase after 20 years of age among both sexes

The association between physical activity and vertebral dimension change in early adulthood:the Northern Finland Birth Cohort 1986 study

Abstract Small vertebral size is a well-known risk factor for vertebral fractures. To help understanding the factors behind vertebral size, we aimed to investigate whether physical activity and participation in high-impact exercise are associated with the growth rate of the vertebral cross-sectional area (CSA) among young adults. To conduct our study, we utilized the Northern Finland Birth Cohort 1986 as our study population (n = 375). Questionnaire data about physical activity was obtained at 16, 18 and 19 years of age and lumbar magnetic resonance imaging scans at two timepoints, 20 and 30 years of age. We used generalized estimating equation (GEE) models to conduct the analyses. We did not find any statistically significant associations between vertebral CSA, physical activity, and high-impact exercise in our study sample. We conclude that neither physical activity nor high-impact sports seem to influence the change in vertebral CSA among young adults