Psychometric properties of the Spence Children's Anxiety Scale in a Hong Kong Chinese community sample

This study evaluated the psychometric properties of a widely used self-report anxiety scale-the Spence Children's Anxiety Scale (SCAS) and the associated parent-report version (PSCAS)-in a Hong Kong Chinese community sample. While good psychometric properties of SCAS and PSCAS had been documented in Western cultural contexts (e.g., Australia), no systematic psychometric evaluation of the Chinese-translated SCAS and PSCAS has been published. In this study, psychometric properties of SCAS and PSCAS were examined with respect to four criteria: (a) factor structure, (b) descriptive statistics, (c) convergent validity with an anxiety cognition measure, and (d) internal consistency. Psychometric properties of SCAS and PSCAS for a Chinese community sample were found to be highly comparable with those published on Australian samples, thus providing a solid conceptual foundation for use of the Chinese version of SCAS and PSCAS. © 2011 Elsevier Ltd.postprin

Derivative chromosome 9 deletions in chronic myeloid leukaemia: Interpretation of atypical D-FISH pattern

Background/Aims: New molecular cytogenetic techniques are increasingly applied as a routine investigative tool in haematological malignancies, both at diagnosis and subsequent monitoring. This report describes the interpretation of atypical signal patterns encountered using BCR-ABL dual colour dual fusion fluorescence in situ hybridisation (D-FISH) translocation probes in chronic myeloid leukaemia (CML). Methods: Interphase FISH experiments were carried out using BCR-ABL D-FISH probes in 46 patients with CML at diagnosis and during subsequent disease monitoring. Atypical hybridisation signal patterns were characterised by molecular cytogenetic techniques and correlated with conventional karyotyping. Results: Two patients showed atypical interphase D-FISH patterns with one orange, one green, and one fusion (1O1G1F) signal. The presence of BCR-ABL gene fusion was documented by a dual colour single fusion (S-FISH) probe. The submicroscopic deletion of the ABL-BCR fusion gene on the derivative chromosome 9 in these cases was subsequently characterised by metaphase FISH on relocated G banded metaphases. Conclusions: Atypical interphase D-FISH patterns should not be interpreted in isolation and should be considered in conjunction with other cytogenetic or molecular genetic investigations.published_or_final_versio

Concomitant plasmacytoma and B cell lymphoma with discordant light chain expression but clonal identity

Letter to the editorpublished_or_final_versionSpringer Open Choice, 25 May 201

Enucleation of painful blind eye for refractory intraocular lymphoma after dose-limiting chemotherapy and radiotherapy

published_or_final_versionSpringer Open Choice, 25 May 201

Sustained and repeated response of relapsed acute promyelocytic leukaemia to intravenous or oral arsenic trioxide

published_or_final_versio

Elemental and mineralogical composition of metal-bearing neutralisation sludges, and zinc speciation – A review

Zinc (Zn) in sludges from neutralisation of acidic emissions is a potential environmental pollutant and an element of interest for recovery. Findings regarding the elemental and mineralogical composition of such wastes were aggregated from the literature and examined together for a better understanding of management options, with a focus on Zn. Zn concentrations ranged from 0.006-22% in 46 acid mine drainage sludges, 0.009%-43% in 72 metal-finishing sludges, 0.024%-11.5% in 32 pyrometallurgical sludges, and 1.71-55.7% in 14 Zn production sludges. The main mineralogical characterization technique was X-ray diffraction, which found the dominant minerals to be calcite, gypsum, quartz, and iron oxides, but could not identify considerable proportions of amorphous phases. More than 60 mineral phases were observed. Crystalline Zn compounds identified included oxides, hydroxides, sulfates, sulfides, and metallic Zn; spinel, olivine and carbonate dominated in pyrometallurgical sludges. Zn may also be present in crystalline phases of low concentration, solid solution, and/or amorphous phases, which could be identified and characterised in more detail using other techniques. Overall, it is concluded that Zn occurs in high concentrations and includes phases that have high potential environmental mobility. Zn recovery seems feasible and would also enable harmless disposal of the residual

Unmanipulated bone marrow transplantation from one-Hla antigen mismatched siblings carries high transplant-related mortality compared with the Hla-identical counterparts

published_or_final_versio

Intensive chemotherapy with peripheral blood stem cell (PBSC) support in the treatment of leukemia relapse after allogeneic bone marrow transplantation: clinical results and chimerism findings

published_or_final_versio

Sustained and repeated response of relapsed acute promyelocytic leukemia (APL) to arsenic therapy

published_or_final_versio