Skin manifestations of Bartonella infections.

peer reviewe

Mucositis por Mycoplasma pneumoniae: ¿Una forma atípica del síndrome de Stevens-Johnson?

Una de las manifestaciones dermatológicas relacionadas a la infección por Mycoplasma pneumoniae es el síndrome de Stevens – Johnson (SSJ) donde predomina la mucositis sobre la afectación cutánea, por este motivo ha sido considerado como una nueva entidad separada del espectro del SSJ denominada “Exantema mucocutáneo inducido por Mycoplasma” (MIRM), por sus características clínicas y pronósticas más benignas. A pesar de ello, aún existe controversia si el MIRM es una entidad independiente del SSJ o es una forma más leve dentro del espectro de esta enfermedad. Se describe un caso clínico con el cual se discute esta nueva clasificación. PALABRAS CLAVE: Mycoplasma pneumoniae, mucositis, síndrome de Stevens – Johnson (DeCS) DOI: http://dx.doi.org/10.17268/rmt.2020.v16i01.1

Un nuevo enfoque sobre la epidemioloiga de las onicomicosis.

Onychomycoses represent a group of nail affections caused by one or more fungi. Whether aging represents a risk factor for developing onychomycosis, remains a question. In the present work, we studied the variations in frequency and prevalence of onychomycoses and non-mycotic onychodystrophies according to age. Our results show that there is an increase in the frequency and prevalence of onychomycoses and non-mycotic onychodystrophies predominantly in patients over forty years of age

Genophotodermatoses.

peer reviewedGenophotodermatoses can result from a defect in melanin synthesis, a defect in DNA repair or a congenital photosensibility

Treatment failures and relapses in onychomycosis: a stubborn clinical problem.

The therapeutic outcome of onychomycoses is uncertain. Comparative short-term efficacy studies on antifungals abound and report contradictory findings. Few unbiased follow-up studies have scrutinized the long-term outcome. Basically, none of the current antifungals can guarantee cure in all instances. In addition, relapses are not rare. The causes of therapeutic failure in onychomycoses are multiple. The most important are the lack of diagnostic accuracy, inadequate antifungal choice or delivery modality, and presence of dormant conidia, sequestrated mycelium pockets or resistant fungal species. The concept of fungicidal drug derived from selected in vitro studies appears irrelevant in clinical practice

Drug of the month. Voriconazole (Vfend).

peer reviewedInvasive fungal infections are a rare but important cause of morbidity and mortality among patients with severely compromised host defenses. Despite considerable advances in antifungal therapies over the past years, invasive mycoses remain a stubborn and dramatic problem. Voriconazole is a new triazole antifungal agent which confers a relative survival benefit in fluconazole-resistant invasive candidiasis, and in invasive aspergillosis, fusariosis and Scedosporium infections as well

Syphilis: a STD back to us.

peer reviewedSexually transmitted diseases (STD) show frequent epidemiological changes. We report a case of secondary syphilis diagnosed in a 32-year old woman during post-partum. The disease, although showing a typical presentation, raises the problem of dating with precision the contamination time. This is of importance for treating the newborn at risk of congenital syphilis. We highlight the constant attention that should be brought to disclose this venereal disease that shows so variable clinical and histological presentations. Syphilis seems on the rise in the Mosan valley and in some cities where prostitution is imported from Eastern Europe and Africa