Pearson’s Correlation among Five Porcine Breast Milk Exosomes Samples.^a

a<p>The correlation was calculated for each pair of samples, based on the counts of identified plant miRNAs. The P-values are given in brackets.</p

The lengths distribution examination of the exogenous-origin sRNA sequences.

<p>The summary of the sequence length distribution generated from (A) the <i>S. scrofa</i> and (B) <i>H. sapiens</i> tags, respectively, which remained after all processing and verification steps of the preformed bioinformatics analysis. Most of the generated reads were 21–24 nucleotides long.</p

List of Several Interesting Putative Human Targets for Select Plant miRNAs and Potential Impact of These Food-Derived Molecules on Human Organism.

<p>List of Several Interesting Putative Human Targets for Select Plant miRNAs and Potential Impact of These Food-Derived Molecules on Human Organism.</p

Workflow of human and pig breast milk exosomes sequencing data analysis.

<p>The reads collected from the 4 <i>H. sapiens</i> and 8 <i>S. scrofa</i> data sets were, each individually, cleaned and matched to known plant miRNAs to select all putative food-derived molecules. The matched tags were further subjected to few filtering steps, which resulted in elimination of all human and pig ncRNAs, repeat-associated RNAs, exon fragments and sequences successfully mapped to reference genomes, respectively. The remained reads were additionally examined to find and discard tags that with high probability represent specific microbiome sequences. As a second part of the analysis, the human targets prediction and annotation were carried out for select plant miRNAs. The aforementioned steps are detail described in the Materials and Methods section. Blue hexagons represent the data used and generated in the following processing/filtering steps (green rectangles) of the analysis.</p