Low-cost electrochemical impedance spectroscopy system for corrosion monitoring of metallic antiquities and works of art

Electrochemical impedance spectroscopy (EIS) is recognized to be a powerful and noninvasive technique to test the integrity of protective coatings on memorials, but commercial EIS systems are rather costly though versatile devices. This paper describes a low cost and portable EIS system that is based on a compact digital signal processor (DSP) board and embeds the potentiostatic function so that it can be used without requiring an external potentiostat. The software that runs on the DSP is designed to analyze the electrochemical impedance only in a reduced frequency range in order to produce a simple corrosion alert result. The device is equipped with a digital interface and can be connected to a personal computer to carry out a complete frequency analysis and perform a more complex data processing

Exposure-Tolerant Imaging Solution forCultural Heritage Monitoring

This paper describes a simple and cheap solution specifically designed for monitoring the degradation of thin coatings employed for metal protection. The proposed solution employs a commercial photocamera and a frequency-domain-based approach that is capable of highlighting the surface uniformity changes due to initial corrosion. Even though the proposed solution is specifically designed to monitor the long-time performance of protective coatings employed for the restoration of silver artifacts, it can be successfully used also for assessing the conservation state of other ancient metallic works of art. The proposed solution is made tolerant to exposure changes by using a procedure for sensor nonlinearity identification and correction, does not require a precise lighting control, and employs only free open-source software, so that its overall cost is very low and can be used also by not specifically trained operator

Handheld-Impedance-Measurement System with seven-decade capability and potentiostatic function

This paper describes design and test of a new impedance-measurement system for nonlinear devices that exhibits a seven-decade range and works down to a frequency of 0.01 Hz. The system is specifically designed for electrochemical measurements, but the proposed architecture can be employed in many other fields where flexible signal generation and analysis are required. The system employs an unconventional signal generator based on two pulsewidth modulation (PWM) oscillators and an autocalibration system that allows uncertainties of less than 3% to be obtained over a range of 1 kΩ to 100 GΩ. A synchronous demodulation processing allows the noise superimposed to the low-amplitude input signals to be made negligibl

Electrochemical measurements and microscopy on hybrid coatings for metallic artefacts

Electrochemical Impedance Spectroscopy and Scanning ElectroChemical Microscopy are employed to characterize innovative hybrid coatings, which can be proposed for the corrosion protection of cultural metallic artefacts. In this paper hybrid TEOS and Graphene Oxide epoxy coatings have been tested in view of their possible employment as protective coatings for archaeological iron artefacts. The coatings have been deposited on low carbon steel and exposed to aggressive solutions. The performance of EIS and ElectroChemical Microscopy have been compared with the final aim of investigating if the proposed measuring approaches can easily give useful results to help the restorers in the choice of the conservation methodology. Comparing results from the two techniques can give a deeper knowledge of the coating performance and of their degradation mechanism

Wireless sensor network for indoor and outdoor atmospheric monitoring in culture heritage

Environmental monitoring is of paramount importance in the preservation of cultural heritage. Climatic conditions affect significantly the conservation state of cultural heritage assets and can accelerate their degradation process. Thus, a continuous and accurate monitoring system is required in most of the cultural heritage sites to control the micro-climate parameters. The proposed environmental monitoring system complies with the typical constraints required in the cultural heritage field and it is effectively employed in different monitoring campaigns still in progress. The system employs small sensor nodes that measure local temperature and humidity and wireless transmit acquired data to a dedicated receiver. The system is very flexible and can be adapted to serve almost every location, both indoor and outdoor. Moreover, the system can optionally provide a remote real-time data access using a cloud infrastructure when Internet and a power source are available in the heritage site

In situ EIS measurements on Colombian bronze statues

An in situ assessment of the conservation state of some bronze statues exposed outdoor has been carried out in Colombia, in the historical site surrounding the Puente de Boyacá. Electrochemical Impedance Spectroscopy (EIS) measurements have been performed by using a portable electrochemical interface and by using measuring probes, specifically designed to be capable of working also on slanted surfaces, to be non invasive, and to be removable without damaging the statues with the final aim of developing a long-lasting maintenance methodology for this important complex of Colombian bronze statues

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

SummaryBackground Azithromycin has been proposed as a treatment for COVID-19 on the basis of its immunomodulatoryactions. We aimed to evaluate the safety and efficacy of azithromycin in patients admitted to hospital with COVID-19.Methods In this randomised, controlled, open-label, adaptive platform trial (Randomised Evaluation of COVID-19Therapy [RECOVERY]), several possible treatments were compared with usual care in patients admitted to hospitalwith COVID-19 in the UK. The trial is underway at 176 hospitals in the UK. Eligible and consenting patients wererandomly allocated to either usual standard of care alone or usual standard of care plus azithromycin 500 mg once perday by mouth or intravenously for 10 days or until discharge (or allocation to one of the other RECOVERY treatmentgroups). Patients were assigned via web-based simple (unstratified) randomisation with allocation concealment andwere twice as likely to be randomly assigned to usual care than to any of the active treatment groups. Participants andlocal study staff were not masked to the allocated treatment, but all others involved in the trial were masked to theoutcome data during the trial. The primary outcome was 28-day all-cause mortality, assessed in the intention-to-treatpopulation. The trial is registered with ISRCTN, 50189673, and ClinicalTrials.gov, NCT04381936.Findings Between April 7 and Nov 27, 2020, of 16 442 patients enrolled in the RECOVERY trial, 9433 (57%) wereeligible and 7763 were included in the assessment of azithromycin. The mean age of these study participants was65·3 years (SD 15·7) and approximately a third were women (2944 [38%] of 7763). 2582 patients were randomlyallocated to receive azithromycin and 5181 patients were randomly allocated to usual care alone. Overall,561 (22%) patients allocated to azithromycin and 1162 (22%) patients allocated to usual care died within 28 days(rate ratio 0·97, 95% CI 0·87–1·07; p=0·50). No significant difference was seen in duration of hospital stay (median10 days [IQR 5 to >28] vs 11 days [5 to >28]) or the proportion of patients discharged from hospital alive within 28 days(rate ratio 1·04, 95% CI 0·98–1·10; p=0·19). Among those not on invasive mechanical ventilation at baseline, nosignificant difference was seen in the proportion meeting the composite endpoint of invasive mechanical ventilationor death (risk ratio 0·95, 95% CI 0·87–1·03; p=0·24).Interpretation In patients admitted to hospital with COVID-19, azithromycin did not improve survival or otherprespecified clinical outcomes. Azithromycin use in patients admitted to hospital with COVID-19 should be restrictedto patients in whom there is a clear antimicrobial indication