42,196 research outputs found
Organizing International Technological Collaboration in Subcontractor Relationships An Investigation of the Knowledge-Stickyness Problem
Technological knowledge is often claimed to be context-bound and sticking to local surroundings. This paper investigates how technological knowledge can be exchanged in international subcontractor relationships, using relationship-oriented organizational practices. Five hypotheses concerning such practices are tested. It is shown that the use of relationshiporiented practices varies with exports and the active development of subcontractors in product and process development activities. Moreover, international development-oriented subcontractors are more likely to use interpersonal exchange, electronic data interchange and formalized contracts than other types of subcontractors. Research implications as well as managerial implications are derived.Subcontracting, knowledge, international division og labour
Bursts and Shocks in a Continuum Shell Model
We study a "burst" event, i. e. the evolution of an initial condition having
support only in a finite interval of k-space, in the continuum shell model due
to Parisi. We show that the continuum equation without forcing or dissipation
can be explicitly written in characteristic form and that the right and left
moving parts can be solved exactly. When this is supplemented by the
appropriate shock condition it is possible to find the asymptotic form of the
burst.Comment: 15 pages, 2 eps figures included, Latex 2e. Contribution to the
proceedings of the conference: Disorder and Chaos, in honour of Giovanni
Paladin, September 22-24, 1997, in Rom
Internal computational fluid mechanics on supercomputers for aerospace propulsion systems
The accurate calculation of three-dimensional internal flowfields for application towards aerospace propulsion systems requires computational resources available only on supercomputers. A survey is presented of three-dimensional calculations of hypersonic, transonic, and subsonic internal flowfields conducted at the Lewis Research Center. A steady state Parabolized Navier-Stokes (PNS) solution of flow in a Mach 5.0, mixed compression inlet, a Navier-Stokes solution of flow in the vicinity of a terminal shock, and a PNS solution of flow in a diffusing S-bend with vortex generators are presented and discussed. All of these calculations were performed on either the NAS Cray-2 or the Lewis Research Center Cray XMP
A Hyperstable Miniprotein: Additive Effects of D- and L-Ala Substitutions
The effects of alanine substitutions in each helical segment of the structure, and Gly to D-Ala mutations at sites where glycines have positive phi angles in the Trp-cage miniprotein are reported. The effects of the stabilizing mutation were additive, yielding a 20-residue construct (Tm = 83^o^C). Gly to L-Ala substitutions were uniformly destabilizing ([DELTA][DELTA]G~F~ > 11 kJ/mol): the preference for a D-Ala can be as large as 16 kJ/mol. Glycine to D-Ala mutations are validated as a strategy for the design of hyperstable miniprotein scaffolds suitable for stereospecific pharmacophore display
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