Real-Time genomic surveillance for SARS-CoV-2 variants of concern, Uruguay

We developed a genomic surveillance program for realtime monitoring of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in Uruguay. We report on a PCR method for SARSCoV- 2 VOCs, the surveillance workflow, and multiple independent introductions and community transmission of the SARS-CoV-2 P.1 VOC in Uruguay

Emergence and spread of a B.1.1.28-derived P.6 lineage with Q675H and Q677H spike mutations in Uruguay

Uruguay controlled the viral dissemination during the first nine months of the SARS-CoV-2 pandemic. Unfortunately, towards the end of 2020, the number of daily new cases exponentially increased. Herein, we analyzed the country-wide genetic diversity of SARS-CoV-2 between November 2020 and April 2021. We identified that the most prevalent viral variant during the first epidemic wave in Uruguay (December 2020–February 2021) was a B.1.1.28 sublineage carrying Spike mutations Q675H + Q677H, now designated as P.6, followed by lineages P.2 and P.7. P.6 probably arose around November 2020, in Montevideo, Uruguay’s capital department, and rapidly spread to other departments, with evidence of further local transmission clusters; it also spread sporadically to the USA and Spain. The more efficient dissemination of lineage P.6 with respect to P.2 and P.7 and the presence of mutations (Q675H and Q677H) in the proximity of the key cleavage site at the S1/S2 boundary suggest that P.6 may be more transmissible than other lineages co-circulating in Uruguay. Although P.6 was replaced by the variant of concern (VOC) P.1 as the predominant lineage in Uruguay since April 2021, the monitoring of the concurrent emergence of Q675H + Q677H in VOCs should be of worldwide interest

Recurrent dissemination of SARS-CoV-2 through the Uruguayan–Brazilian border

Uruguay is one of the few countries in the Americas that successfully contained the coronavirus disease 19 (COVID-19) epidemic during the first half of 2020. Nevertheless, the intensive human mobility across the dry border with Brazil is a major challenge for public health authorities. We aimed to investigate the origin of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains detected in Uruguayan localities bordering Brazil as well as to measure the viral flux across this ∼1,100 km uninterrupted dry frontier. Using complete SARS-CoV-2 genomes from the Uruguayan–Brazilian bordering region and phylogeographic analyses, we inferred the virus dissemination frequency between Brazil and Uruguay and characterized local outbreak dynamics during the first months (May–July) of the pandemic. Phylogenetic analyses revealed multiple introductions of SARS-CoV-2 Brazilian lineages B.1.1.28 and B.1.1.33 into Uruguayan localities at the bordering region. The most probable sources of viral strains introduced to Uruguay were the Southeast Brazilian region and the state of Rio Grande do Sul. Some of the viral strains introduced in Uruguayan border localities between early May and mid-July were able to locally spread and originated the first outbreaks detected outside the metropolitan region. The viral lineages responsible for Uruguayan urban outbreaks were defined by a set of between four and 11 mutations (synonymous and non-synonymous) with respect to the ancestral B.1.1.28 and B.1.1.33 viruses that arose in Brazil, supporting the notion of a rapid genetic differentiation between SARS-CoV-2 subpopulations spreading in South America. Although Uruguayan borders have remained essentially closed to non-Uruguayan citizens, the inevitable flow of people across the dry border with Brazil allowed the repeated entry of the virus into Uruguay and the subsequent emergence of local outbreaks in Uruguayan border localities. Implementation of coordinated bi-national surveillance systems is crucial to achieve an efficient control of the SARS-CoV-2 spread across this kind of highly permeable borderland regions around the world

Las respuestas a los conflictos de pareja desde una perspectiva de género: la inteligencia emocional como patrón diferencial

Conflicts that arise in romantic relationships can be one of the greatest causes of suffering when they are not faced appropriately. Through two studies, this research analyses the differential effect of gender and the influence of emotional intelligence on conflict-facing responses, as well as their consequences at an individual and relationship level. In Study 1, we examined the existence of gender differences during conflicts through four independent samples of subjects (N = 727). After meta-analysing the results, we observed that women responded more expressively and loyally to conflict, while men had a more negligent response. In our observations in Study 2 (N = 185), emotional intelligence became a key factor in promoting a constructive response to face conflicts that is adopted by both women and men. Moreover, emotional intelligence finally favours their psychological well-being and satisfaction with the relationship. This research shows the importance of emotional skills in confronting conflicts that originate in intimate contexts such as romantic relationships and their consequences to both men and women.Depto. de Psicología Social, del Trabajo y DiferencialFac. de PsicologíaTRUEpu

Untangling the effects of partner responsiveness on health and well-being: the role of perceived control

Perceived partner responsiveness (PPR)—the extent to which people feel understood, cared for, and appreciated—has been identified as an organizing principle in the study of close relationships. Previous work indicates that PPR may benefit physical health and well-being, but how PPR is associated with personal benefits is less clear. One cognitive mechanism that may help to explain these associations is perceived control. Here we tested two competing models (moderation vs. mediation) in which we assessed whether perceived control might explain how PPR impacts health, well-being, and mortality in a 20-year longitudinal study of adults (N = 1,186). We found that PPR has a long-term positive association with health, well-being, and mortality via increased perceived control and, in turn, decreased negative affect reactivity to daily stressors. These findings have important implications for understanding the cognitive mechanisms that link PPR to health and well-being.Depto. de Psicología Social, del Trabajo y DiferencialFac. de PsicologíaTRUEpu

Mixed and Conflicted: The Role of Ambivalence in Romantic Relationships in Light of Attractive Alternatives

People in romantic relationships tend to have positive feelings toward their partner and want their relationship to last. However, maintaining a romantic relationship over time is challenging, and people can often experience mixed and conflicting feelings (i.e., ambivalence) toward their significant other. While research has identified the serious consequences that ambivalence can have for personal and relational well-being, very little is known about the factors that can lead people to experience ambivalence in relationships. The present work examines how extradyadic desire (i.e., desire for someone other than the partner), a common difficulty people face in the context of monogamy, is a situation in which people feel more ambivalent toward their partner. In three studies (N = 1,178) using experimental, daily diary, and longitudinal approaches, we find that feelings of desire for an attractive alternative increase ambivalence toward the current partner, above and beyond how much people actually value their partner, and that this has short- and long-term negative consequences for personal and relational well-being. Furthermore, while most people could identify an attractive alternative in their life, desire for the alternative—rather than just their presence—seems to play a stronger role in increasing ambivalence. This work highlights the emotional processes through which attractive alternatives pose a threat to romantic relationships and the role that ambivalence plays in daily life and over time.Depto. de Psicología Social, del Trabajo y DiferencialFac. de PsicologíaTRUEpu

How Power Affects Emotional Communication During Relationship Conflicts: The Role of Perceived Partner Responsiveness

Prior research indicated that lack of power leads to emotional suppression and low emotional expression during conflicts among strangers. However, little is known about how power affects emotional inhibition in close relationships, where partners are highly interdependent, and achieving one’s goals greatly depends on their partner’s cooperation. In three studies among romantic couples (total N = 994), we examined whether (a) power is related to emotional inhibition during conflicts, (b) perceived partner responsiveness moderates this effect and, (c) which conflict-resolution responses are subsequently enacted. Findings consistently showed that powerless individuals were more likely to inhibit their emotions and consequently to use passive responses during conflicts. However, this only occurred when they perceived lack of responsiveness from their partner. If the partner was perceived as responsive (i.e., showed care, validation, and understanding), power was not related to emotional inhibition and passive resolutions. The importance of partner’s responses in relation to power asymmetry is discussed.Depto. de Psicología Social, del Trabajo y DiferencialFac. de PsicologíaTRUEpu

Housework, Health, and Well-Being in Older Adults: the Role of Socioeconomic Status

For most adults, household chores are undesirable tasks yet need to be completed regularly. Previous research has identified absolute hours spent on household chores and one’s perceived fairness of the housework distribution as predictors of romantic relationship quality and well-being outcomes. Drawing from the Equity Theory, we hypothesized that perceived fairness acts as an underlying psychological mechanism linking household chores hours to long-term effects of relationship quality, well-being, physical health, and sleep quality in a sample of 2,644 married and cohabiting adults from the Midlife Development in the U.S. study. Additionally, following the Reserve Capacity Model, socioeconomic status (SES) was tested as a moderator because of its association with exposure to stressors and psychological resources which contribute to perceived fairness. Moderated mediation results showed significant indirect effects of household chore hours through perceived fairness on prospective measures of well-being, marital quality, physical health, and sleep dysfunction among individuals of lower SES but not higher SES when controlling for age, sex, and paid work hours. These results highlight the importance of perceived fairness and the influence of SES in the links among household chores and long-term relationship processes, health, and well-being.Depto. de Psicología Social, del Trabajo y DiferencialFac. de PsicologíaTRUEpu

Socioeconomic Status and Psychological Well-Being: revisiting the Role of Subjective Socioeconomic Status

Socioeconomic status (SES) is a complex and multidimensional construct, encompassing both independent objective characteristics (e.g., income or education) and subjective people’s ratings of their placement in the socioeconomic spectrum. Within the growing literature on subjective SES belongingness and psychological well-being, subjective indices of SES have tended to center on the use of pictorial rank-related social ladders where individuals place themselves relative to others by simultaneously considering their income, educational level, and occupation. This approach, albeit consistent with the idea of these social ladders as summative or cognitive SES markers, might potentially constrain individuals’ conceptions of their SES. This research (N = 368; Mage = 39.67, SD = 13.40) is intended to expand prior investigations on SES and psychological well-being by revisiting the role of subjective SES. In particular, it (a) proposes an innovative adaptation of the traditional MacArthur Scale of subjective SES to income, education, and occupation, thus resulting in three separate social ladders; and (b) tests the empirical contribution of such three social ladders to psychological well-being. Overall, our findings showed that the novel education and occupation ladders (excluding the income ladder) are predictive of a significant part of the variance levels of psychological well-being that is not due to canonical objective metrics of SES (i.e., income, education, and occupation), or to the conventional MacArthur Scale of subjective SES. Although preliminary, these results underscore the need to further reconsider (subjective) SES-related conceptualization and measurement strategies to gather a more comprehensive understanding of the SES-psychological well-being link.Depto. de Psicología Social, del Trabajo y DiferencialFac. de PsicologíaTRUEpu

Assessment of the effects of health and financial threat on prosocial and antisocial responses during the COVID-19 pandemic: the mediating role of empathic concern

This research aims to elucidate the connection of perceived health and financial threat linked to the COVID-19 pandemic with the willingness to engage in prosocial and antisocial behaviors, while also testing the potential mediating role of empathic concern. During the lockdown period, a sample of Spanish community members (N = 702) filled in a multi-measure online survey. Our results revealed that (a) COVID-19 health (but not financial) threat predicted a greater tendency to express prosocial actions, (b) none of these forms of COVID-19 threat predicted antisocial inclinations, and (c) empathic concern mediated the effects of COVID-19 health threat on both prosocial and antisocial tendencies. Findings speak to the ongoing debate about whether individuals most psychologically impacted by the pandemic would tend to respond in a more prosocial or antisocial manner.Depto. de Psicología Social, del Trabajo y DiferencialFac. de PsicologíaTRUEpu