On-going randomized controlled trials evaluating treatment strategies for resectable locally advanced hypopharyngeal squamous cell carcinoma.

On-going randomized controlled trials evaluating treatment strategies for resectable locally advanced hypopharyngeal squamous cell carcinoma.</p

PRISMA flow-chart.

PRISMA flow-chart.</p

Forest plots for various comparisons and outcomes.

a: Overall Survival. b: Disease-Free Survival. c: Any Recurrence. d: Local Recurrence. e: Loco-Regional Recurrence. f: Distal Recurrence. g: Treatment-Related Toxicity. h: Laryngectomy-Free Survival.</p

Summary of treatment-related toxicity.

Summary of treatment-related toxicity.</p

Search strategy.

(DOCX)</p

Figure demonstrating risk of bias (ROB).

Figure demonstrating risk of bias (ROB).</p

Summary of findings.

(DOCX)</p

Response assessment following induction chemotherapy and larynx preservation rates.

Response assessment following induction chemotherapy and larynx preservation rates.</p

Characteristics of included studies.

Characteristics of included studies.</p

PRISMA checklist.

(TIF)</p