Modulation of small intestinal small chain fatty acid profile induced by 2 weeks consumption with 2 fermented milk products; a randomized, exploratory, cross-over, double blind, controlled study in ileostomy patients

Short chain fatty acid profiling of ileostomy samples. 16 volunteers received yogurt, L. rhamnosus or placebo in different orders. Ileostomy samples were collected in the morning after breakfast at the beginning and at the end of the 2 weeks intervention period. The samples were collected for the INSIDE explorative dietary study. The study was aimed to characterize the impact of fermented food may have on the small intestinal environment and systematically

TruCulture: Systemic immune adaptation and responsiveness induced by 2-wks consumption with 2 fermented milk products; a randomized, exploratory, cross-over, double blind, controlled study in ileostomy patients

Immunophenotyping of whole blood after ex-vivo stimulus. The samples were collected for the INSIDE explorative dietary study. The study was aimed to characterize the impact of fermented food may have on the small intestinal microbiota and systematically

Metabolites Serum: Serum metabolites changes induced by 2-wks consumption with 2 fermented milk products; a randomized, exploratory, cross-over, double blind, controlled study in ileostomy patients

Metabolites profiling of blood samples. The samples were collected for the INSIDE explorative dietary study. The study was aimed to characterize the impact of fermented food may have on the small intestinal microbiota and systematically

Biomarkers: Blood biomarkers and proteome response by 2-wks consumption with 2 fermented milk products; a randomized, exploratory, cross-over, double blind, controlled study in ileostomy patients

Biomarkers profiling of human blood serum. The samples were collected for the INSIDE explorative dietary study. The study was aimed to characterize the impact of fermented food may have on the small intestinal microbiota and systematically

Urine metabolites changes induced by 2-wks consumption with 2 fermented milk products; a randomized, exploratory, cross-over, double blind, controlled study in ileostomy patients

Metabolites profiling of urine samples. The samples were collected for the INSIDE explorative dietary study. The study was aimed to characterize the impact of fermented food may have on the small intestinal microbiota and systematically

PBMCs: Systemic immune adaptation and blood transcriptional changes induced by 2-wks consumption with 2 fermented milk products; a randomized, exploratory, cross-over, double blind, controlled study in ileostomy patients

Transcriptomic profiling of human Peripheral Blood Mononuclear Cells (PBMCs). The samples were collected for the INSIDE explorative dietary study. The study was aimed to characterize the impact of fermented food may have on the small intestinal microbiota and systematically

Modulation of gastro-intestinal permeability induced by 2 weeks consumption with 2 fermented milk products; a randomized, exploratory, cross-over, double blind, controlled study in ileostomy patients

Sugar permeability test in urine samples. 16 volunteers received treatments in different orders (Placebo, L. rhamnosus, Yogurt) and urine was collected after 2 and 5 hours. The samples were collected for the INSIDE explorative dietary study. The study was aimed to characterize the impact of fermented food may have on the small intestinal microbiota and systematically. Sucrose and Lactulose content in the urine was measured. Sucrose is hydrolyzed in the duodenum, and is therefore a good marker for gastroduodenal permeability, measured in 0-5h urine. Lactulose can permeate through the paracellular route and rhamnose through the transcellular route in the small intestine. The ratio in 0-5h urine is mainly used for general assessment of the SI permeability

Metatranscriptome: Modulation of small intestinal microbial activity induced by 2 weeks consumption with 2 fermented milk products; a randomized, exploratory, cross-over, double blind, controlled study in ileostomy patients

Ileostomy effluent samples were collected for metatranscriptomic profiling. The samples were collected for the INSIDE explorative diatry study. The study was aimed to characterize the impact of fermented food may have on the small intestinal microbiota and systematically. Please note: the data files belonging to this dataset comprise a total size of 173 GB. Due to its size, the data is archived on DANS secure storage outside of EASY. A file list with an overview of all available files is available on the Data files tab. Please contact DANS in order to obtain acccess to the files