Loss of the definition of the VOF in the domain in case of high and reversed ΔP across the valve.

<p>In black the cells filled with fluid, in white the cells filled with void.</p

Grid formulation for the Eulerian (upper panel) and the ALE (lower panel) methods, in two consequent time-steps (from left to right) for the 2D aortic valve with flexible leaflets.

<p>Grid formulation for the Eulerian (upper panel) and the ALE (lower panel) methods, in two consequent time-steps (from left to right) for the 2D aortic valve with flexible leaflets.</p

Computational time required by the two techniques.

<p>In the 3D case, for the ALE the time of the partial simulation is reported, while for the IB-FSI the time for the complete simulation is listed.</p

Left panel: displacement of the nodulus of Arantio, comparison between an IB-FSI and a structural simulation.

<p>Right panel: kinematic of the leaflets in significant time-points of the heart cycle until diastole (IB-FSI). The colour scale indicates the magnitude of the displacement calculated from the initial configuration.</p

Number of the mesh elements in the different set-ups.

<p>Number of the mesh elements in the different set-ups.</p