Methodical basis of organizational design subsystem of knowledge management in corporations in the context of organizational development Методические основы формирования подсистемы управления знаниями в корпорациях в контексте организационного развития

The article is devoted to the formulation of the methodical basis of the process of organizational design in the field of knowledge management, the research of their role in future organizational development of the corporation.Статья посвящена формулированию методических основ при осуществлении процесса организационного проектирования в области управления знаниями, исследованию их роли в дальнейшем организационном развитии корпорации

Influence of absorbed energy distribution along beam radius on ignition threshold of condensed explosives

The criterion of the condensed explosive ignition by the electron beam, which takes into account Gaussian distribution of electron density along the beam radius, has been obtained. It has been shown that radial heat removal of the absorbed energy leads to the increase in critical ignition energy if the effective track length of electrons in a solid is commensurate with the beam radius. The critical energy of PETN initiation by the electron beam has been calculated

Inventions in the Area of Nanomaterials and Nanotechnologies. Part III

Introduction. Advanced technologies inspire people by demonstrating the latest achievements (materials, methods, systems, technologies, devices etc.) that dramatically change the world. This, first of all, concerns nanotechnological inventions designed by scientists, engineers and specialists from different countries. Main part. The article provides an abstract overview of inventions of scientists, engineers and specialists from different countries: Russia, USA, Turkmenistan, Japan et al. The results of the creative activity of scientists, engineers and specialists, including inventions in the field of nanotechnology and nanomaterials allow, when introduced to industry, achieving a significant effect in construction, housing and communal services, and related sectors of the economy. For example, the invention «Modifying additive» is related to the road construction and can be applied in production of asphalt-concrete, including that with utilizing of nanotechnologies. To improve performance characteristics of bitumen and asphalt concrete one can use modifying additive which comprises a mix of carbon nanomaterials. The aim of the invention is to solve the task of creating new technology which could provide obtaining of asphalt concrete with enhanced performance characteristics. The following inventions in the field of nanotechnology can also be interesting for specialists: a method to obtain multi-layered nanocomposite coating; a method of laser surface treatment for steel products; a device to obtain graphene-containing suspension; a method to obtain nanocrystal silicon powder; a self-cleaning material with chemical and biological protection properties; a method of obtaining nanostructured composite material on the basis of aluminum; a device control system with the shape memory effect to manipulate micro- and nanoobjects; a method to form plasmon nanostructures on the object surfaces to provide non-destructive analysis of low concentrations of chemical compounds by Raman spectroscopy et al. Conclusion. One of the most challenging tasks the economy of every country face is to increase industrial competitiveness through technological upgrade. From the side of the state and companies the principal object to control in this process are the people and enterprises dealing with introduction of inventions and new technologies

Modification of the surface layer of the system coating (TiCuN)/substrate (A7) by an intensive electron beam

In order to study the conditions of modification of the surface layer of the system coating (TiCuN)/substrate (A7) an analysis of processes occurring in the surface layer of the system wear-resistant coating/substrate irradiated by an intensive pulsed electron beam at a submillisecond exposure time has been carried out on the example of aluminum and titanium nitride. Irradiation has been carried out under conditions ensuring melting and crystallization of the surface layer of the material by a nonequilibrium phase diagram. It has been experimentally established that irradiation of the system coating (TiCuN)/substrate (A7) by an intensive electron beam is accompanied by changes in the phase composition of the material. It is evident that nanostructuring of the aluminum layer adjacent to the coating, and formation in it of nitride phase particles will contribute to hardening of the surface layer of the material, creating a transition sublayer between a solid coating and a relatively soft volume. The carried out analysis shows that binary nitrides based on TiN1-x are most likely to form under nonequilibrium conditions, since the homogeneity range of this compound is rather large. On the other hand, formation of the ternary compound Ti3CuN, which can be formed after an arc plasma-assisted deposition of titanium nitride of the composition TiCuN and by the subsequent intensive pulsed electron beam exposure, cannot be excluded

Observation of linear and nonlinear light localization at the edges of moiré arrays

We observe linear and nonlinear light localization at the edges and in the corners of truncated moiré arrays created by the superposition of periodic mutually twisted at Pythagorean angles square sublattices. Experimentally exciting corner linear modes in the femtosecond-laser written moiré arrays we find drastic differences in their localization properties in comparison with the bulk excitations. We also address the impact of nonlinearity on the corner and bulk modes and experimentally observe the crossover from linear quasilocalized states to the surface solitons emerging at the higher input powers. Our results constitute the first experimental demonstration of localization phenomena induced by truncation of periodic moiré structures in photonic systems.This research is funded by the research Project No. FFUU- 2021-0003 of the Institute of Spectroscopy of the Russian Academy of Sciences and partially funded by the RSF Grant No. 21-12-00096. F. Y. acknowledges support from Shanghai Outstanding Academic Leaders Plan (Grant No. 20XD1402000) and the NSFC (Grant No. 91950120). S. K. I. and L. T. acknowledge support by Grants No. CEX2019-000910-S and No. PGC2018-097035-B-I00 funded by MCIN/AEI/10.13039/501100011033/FEDER, Fundació Cellex, Fundació Mir-Puig, and Generalitat de Catalunya (CERCA).Peer ReviewedPostprint (published version

Determination of cold-adapted influenza virus (Orthomyxoviridae: <i>Alphainfluenzavirus</i>) polymerase activity by the minigenome method with a fluorescent protein

Introduction. Polymerase proteins PB1 and PB2 determine the cold-adapted phenotype of the influenza virus A/Krasnodar/101/35/59 (H2N2), as was shown earlier. Objective. The development of the reporter construct to determine the activity of viral polymerase at 33 and 37 °C using the minigenome method. Materials and methods. Co-transfection of Cos-1 cells with pHW2000 plasmids expressing viral polymerase proteins PB1, PB2, PA, NP (minigenome) and reporter construct. Results. Based on segment 8, two reporter constructs were created that contain a direct or inverted NS1-GFP-NS2 sequence for the expression of NS2 and NS1 proteins translationally fused with green fluorescent protein (GFP), which allowed the evaluation the transcriptional and/or replicative activity of viral polymerase. Conclusion. Polymerase of virus A/Krasnodar/101/35/59 (H2N2) has higher replicative and transcriptional activity at 33 °C than at 37 °C. Its transcriptional activity is more temperature-dependent than its replicative activity. The replicative and transcriptional activity of polymerase A/Puerto Rico/8/34 virus (H1N1, Mount Sinai variant) have no significant differences and do not depend on temperature

Hairy cell leukemia. Clinical recommendations

Hairy cell leukemia. Clinical recommendation