Palladium-Catalyzed Intramolecular Insertion of Alkenes into the Carbon–Nitrogen Bond of β‑Lactams

The carbon–nitrogen bond of β-lactams is cleaved by palladium(0), and an alkene is intramolecularly inserted therein. The following reductive elimination produces nitrogen-containing benzo-fused tricycles in good to high yields

Enantioselective Insertion of a Carbenoid Carbon into a C–C Bond To Expand Cyclobutanols to Cyclopentanols

When a carbenoid species generated from a tosylhydrazone is reacted with a cyclobutanol in the presence of a chiral rhodium catalyst, a C–C single bond of the cyclobutanol is cleaved, and the carbenoid carbon is inserted therein to furnish a ring-expanded cyclopentanol in an enantioselective manner