Framework for a cooperative program curriculum among elementary, junior, and senior high schools to develop students' qualities and competence in home economics: Proposal for implementing a cooperative program curriculum for encouraging students to develop an understanding of food cultures and deepen their learning

The purpose of this study is to use surveys to clarify students' awareness at the elementary, junior, and senior high school levels of food cultures and their related issues, and to formulate and implement a class program for junior and senior high schools based on the clarified results. The program will develop students' understanding of food cultures and seeks to combine and systematize home economics education among the three levels of schooling. The study found transformations among elementary and junior high school students, in terms of their understanding of the ideas of food cultures and related issues. In addition, class programs were formulated for Grade 9 students, to broaden their views on a range of topics, and for Grade 10 students, to broaden their view of changes over time, both of which ended with successful results

Conception of cooperation curriculum among elementary, junior high and high schools to promote the qualities and abilities of home economics: the common concept and the systematization of the learning contents

家庭科の目標達成のためには，小・中・高等学校が連携してカリキュラム・マネジメントを行うことが重要である。本研究では，中教審答申(平成28 年)で示された「生活の営みに係る見方・考え方」の視点のひとつである「生活文化の継承・創造」を主たるコンセプトとして，連携カリキュラムを構想した。この研究の第１年目にあたる本稿では，カリキュラム案を構想しつつ，現在附属中学校で展開している食生活の題材の成果と課題を検証し，学びのストーリーと学習内容の体系化の検討を踏まえて，パフォーマンス課題案を構想することを目的とした。平成28年度附属中学校３年生（110 名）が各自取り組んだ，「ひろしま・ライスクッキングコンテスト『伝えていきたいわが家の味・ふるさとの味』」の成果を，実践後に提出された「地産地消について」及び「お米やご飯食について」の記述から分析した。その成果と課題を踏まえて，食生活学習展開の改善案を検討した。また，現時点でのカリキュラムの最終段階の資質・能力の構想案と，逆向き設計の考え方に基づいてコンセプトの下位概念としての目標設定案を提示した。さらに，有効なパフォーマンス課題とその評価指標を構想した。It is important for elementary, junior high, and high schools to manage their curriculums in cooperation to achieve the goals of home economics. In this research, we developed a collaborative curriculum, building on the concept of the “succession and creation of the Culture of Life”, which is one of the visions of the “perspectives on and attitudes about living behavior” included in the 2016 report from Japan’s Central Council for Education. We examined the results and assignments of the lesson topics concerning dietary life developed in the attached junior high school of Hiroshima University. Based on this, a performance plan was devised via the systematization of learning stories and learning contents. We analyzed students’ descriptions of “local production for local consumption” and “rice and living on rice” after the “Rice Cooking Contest Hiroshima 2016”. We considered and proposed a new framework of the qualities and abilities in the final stage of the curriculum

家庭科の資質・能力育成のための小・中・高等学校連携カリキュラムの構想 : 食文化概念の整理と深い学びをうながす連携実践の提案

小・中・高校生の「食文化」に対する認識の実態と課題を調査よって明らかし，その結果と食文化概念の整理に基づいて，中学校及び高等学校の授業を構想，実践し，三校種の接続や体系化の課題を追究することを目的とした。その結果，小学生と中学生の間に食文化などの概念認識の変容をみた。また，中学３年生には空間軸よる視点の広がりを，高校１年生には時間軸による広がりを期待して，それぞれ授業を構想し，その成果をみることができた

Targeted deletion of the C-terminus of the mouse adenomatous polyposis coli tumor suppressor results in neurologic phenotypes related to schizophrenia

Background: Loss of adenomatous polyposis coli (APC) gene function results in constitutive activation of the canonical Wnt pathway and represents the main initiating and rate-limiting event in colorectal tumorigenesis. APC is likely to participate in a wide spectrum of biological functions via its different functional domains and is abundantly expressed in the brain as well as in peripheral tissues. However, the neuronal function of APC is poorly understood. To investigate the functional role of Apc in the central nervous system, we analyzed the neurological phenotypes of Apc 1638T/1638T mice, which carry a targeted deletion of the 3′ terminal third of Apc that does not affect Wnt signaling. Results: A series of behavioral tests revealed a working memory deficit, increased locomotor activity, reduced anxiety-related behavior, and mildly decreased social interaction in Apc 1638T/1638T mice. Apc 1638T/1638T mice showed abnormal morphology of the dendritic spines and impaired long-term potentiation of synaptic transmission in the hippocampal CA1 region. Moreover, Apc 1638T/1638T mice showed abnormal dopamine and serotonin distribution in the brain. Some of these behavioral and neuronal phenotypes are related to symptoms and endophenotypes of schizophrenia. Conclusions: Our results demonstrate that the C-terminus of the Apc tumor suppressor plays a critical role in cognitive and neuropsychiatric functioning. This finding suggests a potential functional link between the C-terminus of APC and pathologies of the central nervous system

Large-scale analysis of full-length cDNAs from the tomato (Solanum lycopersicum) cultivar Micro-Tom, a reference system for the Solanaceae genomics

<p>Abstract</p> <p>Background</p> <p>The Solanaceae family includes several economically important vegetable crops. The tomato (<it>Solanum lycopersicum</it>) is regarded as a model plant of the Solanaceae family. Recently, a number of tomato resources have been developed in parallel with the ongoing tomato genome sequencing project. In particular, a miniature cultivar, Micro-Tom, is regarded as a model system in tomato genomics, and a number of genomics resources in the Micro-Tom-background, such as ESTs and mutagenized lines, have been established by an international alliance.</p> <p>Results</p> <p>To accelerate the progress in tomato genomics, we developed a collection of fully-sequenced 13,227 Micro-Tom full-length cDNAs. By checking redundant sequences, coding sequences, and chimeric sequences, a set of 11,502 non-redundant full-length cDNAs (nrFLcDNAs) was generated. Analysis of untranslated regions demonstrated that tomato has longer 5'- and 3'-untranslated regions than most other plants but rice. Classification of functions of proteins predicted from the coding sequences demonstrated that nrFLcDNAs covered a broad range of functions. A comparison of nrFLcDNAs with genes of sixteen plants facilitated the identification of tomato genes that are not found in other plants, most of which did not have known protein domains. Mapping of the nrFLcDNAs onto currently available tomato genome sequences facilitated prediction of exon-intron structure. Introns of tomato genes were longer than those of Arabidopsis and rice. According to a comparison of exon sequences between the nrFLcDNAs and the tomato genome sequences, the frequency of nucleotide mismatch in exons between Micro-Tom and the genome-sequencing cultivar (Heinz 1706) was estimated to be 0.061%.</p> <p>Conclusion</p> <p>The collection of Micro-Tom nrFLcDNAs generated in this study will serve as a valuable genomic tool for plant biologists to bridge the gap between basic and applied studies. The nrFLcDNA sequences will help annotation of the tomato whole-genome sequence and aid in tomato functional genomics and molecular breeding. Full-length cDNA sequences and their annotations are provided in the database KaFTom <url>http://www.pgb.kazusa.or.jp/kaftom/</url> via the website of the National Bioresource Project Tomato <url>http://tomato.nbrp.jp</url>.</p