3 research outputs found
Real-world assessment and characteristics of men with benign prostatic hyperplasia (BPH) in primary care and urology clinics in Spain
Objectives: To describe the real-world demographic and clinical characteristics of patients with lower urinary tract symptoms (LUTS) as a result of benign prostatic hyperplasia (BPH) in Spain.
Methodology: This observational, retrospective, multicentre study conducted in primary care and urology clinics in Spain included men aged â„50 years diagnosed (â€8 years prior to study visit) with LUTS caused by BPH. The primary endpoint was demographic and clinical characteristics; secondary endpoints included disease progression and diagnostic tests across both healthcare settings.
Results: A total of 670 patients were included (primary care: n = 435; urology: n = 235). Most patients had moderate/severe LUTS (74.6%) and prostate volume >30 cc (81.7%), with no differences between settings. More patients had prostate-specific antigen (PSA) â„1.5 ng/mL in primary care (74.5%) versus urology (67.7%). Progression criteria were prevalent (48.9%). Clinical criteria were more commonly used than the International Prostate Symptom Score (IPSS) to evaluate LUTS at diagnosis (primary care: clinical criteria 73.0%; IPSS: 26.9%; urology: clinical criteria 76.5%; IPSS: 23.4%). Proportion of patients with moderate/severe LUTS at diagnosis was lower using clinical criteria than IPSS, and the proportion of patients with 'worsening' LUTS (diagnosis to study visit) was higher when using clinical criteria versus IPSS. In both healthcare settings, the most commonly used diagnostic tests were general and urological clinical history and PSA.
Conclusion: Demographic and clinical characteristics of patients with BPH in Spain were similar in primary care and urology; however, assessment criteria to evaluate LUTS severity differ and are not completely aligned with clinical guideline recommendations. Increased use of recommended assessments may enhance optimal BPH management
Real-world assessment and characteristics of men with benign prostatic hyperplasia (BPH) in primary care and urology clinics in Spain
Objectives: To describe the real-world demographic and clinical characteristics of patients with lower urinary tract symptoms (LUTS) as a result of benign prostatic hyperplasia (BPH) in Spain.
Methodology: This observational, retrospective, multicentre study conducted in primary care and urology clinics in Spain included men aged â„50 years diagnosed (â€8 years prior to study visit) with LUTS caused by BPH. The primary endpoint was demographic and clinical characteristics; secondary endpoints included disease progression and diagnostic tests across both healthcare settings.
Results: A total of 670 patients were included (primary care: n = 435; urology: n = 235). Most patients had moderate/severe LUTS (74.6%) and prostate volume >30 cc (81.7%), with no differences between settings. More patients had prostate-specific antigen (PSA) â„1.5 ng/mL in primary care (74.5%) versus urology (67.7%). Progression criteria were prevalent (48.9%). Clinical criteria were more commonly used than the International Prostate Symptom Score (IPSS) to evaluate LUTS at diagnosis (primary care: clinical criteria 73.0%; IPSS: 26.9%; urology: clinical criteria 76.5%; IPSS: 23.4%). Proportion of patients with moderate/severe LUTS at diagnosis was lower using clinical criteria than IPSS, and the proportion of patients with 'worsening' LUTS (diagnosis to study visit) was higher when using clinical criteria versus IPSS. In both healthcare settings, the most commonly used diagnostic tests were general and urological clinical history and PSA.
Conclusion: Demographic and clinical characteristics of patients with BPH in Spain were similar in primary care and urology; however, assessment criteria to evaluate LUTS severity differ and are not completely aligned with clinical guideline recommendations. Increased use of recommended assessments may enhance optimal BPH management
Real-world therapeutic management and evolution of patients with benign prostatic hyperplasia in primary care and urology in Spain
Objectives: This study aimed to describe the real-world therapeutic management of
patients with lower urinary tract symptoms (LUTS) due to benign prostatic hyperpla-
sia (BPH) (LUTS/BPH) attending primary care and urology clinics in Spain.
Methods: This observational, retrospective, multicentre study included men
â„50 years of age diagnosed with LUTS/BPH (â€8 years prior to study visit) (N = 670).
Therapeutic management according to healthcare service (primary care vs. urology
clinics) or progression criteria, proportion of patients with treatment change, patient
profile according to therapy and evolution of LUTS severity were assessed.
Results: Overall differences were noticed in the management of patients between
healthcare service (P < .001) and with or without progression criteria (P < .05). Most
patients received pharmacological treatment at diagnosis (70.7%; 474/670), which in-
creased at study visit (81.6%; 547/670) with overall similar profiles between primary
care and urology clinics for each therapy. α1-Blockers were the most used pharmaco-
logical treatment across healthcare settings at diagnosis (61.8%; 293/474) and study
visit (51%; 279/547). Only 27.1% (57/210) of patients with progression criteria at diag-
nosis and 35.6% (99/278) at study visit received 5α-reductase inhibitor (5ARI) alone
or in combination with a α1-blocker. Overall, most patients did not change treatment
(60%; 402/670) with a trend of more patients worsening in symptoms when not re-
ceiving α1-blocker plus 5ARI combination therapy.
Conclusion: Most patients with LUTS/BPH received pharmacological treatment;
however, most men with progression criteria did not receive a 5ARI alone or in combi-
nation. These results support the need to reinforce both primary care and urologists
existing clinical guideline recommendations for the appropriate medical management
of patients with LUTS/BPH