Plan de Responsabilidad Social Empresarial Éticos Serrano Gómez Ltda.

Link para visualizar el video de contextualización de la empresa Éticos Serrano Gomez Ltda. https://youtu.be/1cK9FhmsPdgEl Plan de Responsabilidad Social Empresarial de Éticos Serrano Gómez Ltda., que se presenta en este trabajo está contemplado en una cadena de procedimientos y acciones en las cuales la organización sea responsable y amigable con los servicios y productos que ofrece en el ámbito económico, social y ambiental, dando a conocer los objetivos y las estrategias planteadas de cada una de las partes involucradas en el proceso. La forma en que se desarrolla la empresa Éticos Serrano Gómez Ltda., es generando mecanismos colectivos para accionar y mejorar la calidad de vida de sus empleados a través del compromiso propio con la sociedad que apunte a un mundo sostenible y solidario para que las generaciones futuras sigan el camino.The Corporate Social Responsibility Plan of Eticos Serrano Gómez Ltda., that is presented in this work is contemplated in a chain of procedures and actions in which the organization is responsible and friendly with the services and products that it offers in the economic, social and environmental field, making known the objectives and strategies proposed of each of the parties involved in the process. The way in which the company Eticos Serrano Gómez Ltda., is developed is generating collective mechanisms to drive and improve the quality of life of its employees through its own commitment to society that points to a sustainable and supportive world so that future generations follow the path

Surface-enhanced Raman Spectroscopy in urinalysis of hypertension patients with kidney disease

Abstract Arterial hypertension (AH) is a multifactorial and asymptomatic disease that affects vital organs such as the kidneys and heart. Considering its prevalence and the associated severe health repercussions, hypertension has become a disease of great relevance for public health across the globe. Conventionally, the classification of an individual as hypertensive or non-hypertensive is conducted through ambulatory blood pressure monitoring over a 24-h period. Although this method provides a reliable diagnosis, it has notable limitations, such as additional costs, intolerance experienced by some patients, and interferences derived from physical activities. Moreover, some patients with significant renal impairment may not present proteinuria. Accordingly, alternative methodologies are applied for the classification of individuals as hypertensive or non-hypertensive, such as the detection of metabolites in urine samples through liquid chromatography or mass spectrometry. However, the high cost of these techniques limits their applicability for clinical use. Consequently, an alternative methodology was developed for the detection of molecular patterns in urine collected from hypertension patients. This study generated a direct discrimination model for hypertensive and non-hypertensive individuals through the amplification of Raman signals in urine samples based on gold nanoparticles and supported by chemometric techniques such as partial least squares-discriminant analysis (PLS-DA). Specifically, 162 patient urine samples were used to create a PLS-DA model. These samples included 87 urine samples from patients diagnosed with hypertension and 75 samples from non-hypertensive volunteers. In the AH group, 35 patients were diagnosed with kidney damage and were further classified into a subgroup termed (RAH). The PLS-DA model with 4 latent variables (LV) was used to classify the hypertensive patients with external validation prediction (P) sensitivity of 86.4%, P specificity of 77.8%, and P accuracy of 82.5%. This study demonstrates the ability of surface-enhanced Raman spectroscopy to differentiate between hypertensive and non-hypertensive patients through urine samples, representing a significant advance in the detection and management of AH. Additionally, the same model was then used to discriminate only patients diagnosed with renal damage and controls with a P sensitivity of 100%, P specificity of 77.8%, and P accuracy of 82.5%

Seroprevalence and Risk Factors Possibly Associated with Emerging Zoonotic Vaccinia Virus in a Farming Community, Colombia

In 2014, vaccinia virus (VACV) infections were identified among farmworkers in Caquetá Department, Colombia; additional cases were identified in Cundinamarca Department in 2015. VACV, an orthopoxvirus (OPXV) used in the smallpox vaccine, has caused sporadic bovine and human outbreaks in countries such as Brazil and India. In response to the emergence of this disease in Colombia, we surveyed and collected blood from 134 farmworkers and household members from 56 farms in Cundinamarca Department. We tested serum samples for OPXV antibodies and correlated risk factors with seropositivity by using multivariate analyses. Fifty-two percent of farmworkers had OPXV antibodies; this percentage decreased to 31% when we excluded persons who would have been eligible for smallpox vaccination. The major risk factors for seropositivity were municipality, age, smallpox vaccination scar, duration of time working on a farm, and animals having vaccinia-like lesions. This investigation provides evidence for possible emergence of VACV as a zoonosis in South America.https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000318507https://orcid.org/0000-0002-8093-0544https://scienti.minciencias.gov.co/gruplac/jsp/visualiza/visualizagr.jsp?nro=00000000008981jose.usmec@[email protected]://scholar.google.com.co/citations?user=cU2KyT4AAAAJ&hl=e