Study Features Associated with Annual Citation Rate

<p>95% CI = 95% confidence interval</p>†<p>n/a = not applicable (variable was not included in the model)</p>*<p>Since a significant interaction term between these two variables was included in the final multivariable model, their effects are dependent on each other and are presented together.</p

Characteristics of the index article cohort.

<p>Characteristics of the index article cohort.</p

Number and percentage by Engel Classification of participants with TSC undergoing resective epilepsy surgery.

<p>Number and percentage by Engel Classification of participants with TSC undergoing resective epilepsy surgery.</p

Characteristics of included studies.

<p>Predictors reported* a) Gender; b) Age at seizure onset; c) Preoperative seizure frequency; d) Presence of infantile spasms; e) Presence of generalized seizures; f) Age at surgery; g) Preoperative intelligent Quotient score; h) Presence of moderate/severe developmental delay; i) Focal or generalized/multifocal interictal EEG abnormality; j) Focal or generalized/multifocal ictal EEG abnormality; k) Concordant electroencephalographic and radiological studies; l) Tuber burden; m) Focal or multifocal SPECT abnormality; n) Focal or multifocal MEG abnormality; o) Focal or generalized/multifocal interictal invasive EEG abnormality; p) Focal or generalized/multifocal ictal invasive EEG abnormality.</p>**<p>Remaining participants were lost to follow-up.</p>***<p>Author contacted for IPD.</p

Odds ratios, 95% confidence intervals and p values for preoperative predictors of good seizure outcome adjusted for duration of follow-up.

*<p>Statistically significant predictors of postoperative seizure outcome.</p