EVALUATION OF MYOMETRIAL INVASION AND CERVICAL INVOLVEMENT IN TYPE I ENDOMETRIAL CANCER USING DIFFUSION-WEIGHTED MAGNETIC RESONANCE IMAGING

Objective: Surgical procedure and adjuvant treatment of type I endometrial cancer were affected by some variables assessed preoperatively. Diffusion-weighted magnetic resonance imaging (DWI) is a promising modality in evaluating myometrial invasion and cervical involvement, investigating the diagnostic values of DWI in assessing myometrial invasion and cervical involvement. Methods: A cross-sectional study was conducted. This study involved all type I endometrial cancer patients in Dr. Cipto Mangunkusumo Hospital from April 2016 until April 2019. The depth of myometrial invasion and cervical involvement was examined using 1.5-T MR unit. The result was compared to the surgical pathologic findings as the reference standard. Results: 34 types I endometrial cancer patients were enrolled in this study. The sensitivity of DWI in evaluating myometrial invasion and cervical involvement in type I endometrial cancer was 94.12% and 57.14%, while the specificity was 64.71% and 92.59%, respectively. Conclusion: DWI can provide reliable prognostic variable information about the myometrial invasion and cervical involvement in the preoperative preparation of endometrial cancer patients

HUBUNGAN BAKTERIURIA DENGAN KEJADIAN PERSALINAN PRETERM

Background: Preterm delivery remains a major cause of perinatal morbidity and mortality. Asymptomatic bacteriuria will lead to acute pyelonephritis which assumed increases the risk factor of low birth weight infants, preterm delivery, and still birth. The relationship of asymptomatic bacteriuria in the absence of acute pyelonephritis with preterm delivery has been controversial. Bacteriuria examination is expected to prevent preterm delivery. Further research to study the relationship of asymptomatic bacteriuria and preterm delivery may be needed. Design: Cross sectional Location of study: RSUD Bantul and Puskesmas Sewon Result: A total of 118 patients were included in this study. This study showed bacteriuria in 65 patients and no bacteriuria in 53 patients. Most patients in this study were less than 35 years old (80,5%), low educated (91,5%), having low parity (77,1%), and long interval of pregnancy (87,3%). History of preterm delivery was low (5,9%), but history of periodontal disease was high (55,1%). Most patients had low psychological stress level (64,4%). Bivariate and multivariate analysis showed that bacteriuria and history of preterm delivery have significant association with preterm delivery. Bacteriuria associated with preterm delivery with OR 0,321 (95% CI 0,140-9,734), while history of preterm delivery associated with preterm delivery with OR 9,616 (95% CI 1,063-86,976). Conclusion: Bacteriuria reduces incidence of preterm delivery, while history of preterm delivery increases incidence of preterm delivery (p<0,05). Research with method improvement and more sample is needed to study the relationship of bacteriuria and preterm delivery