24 research outputs found
Betriebslastkollektive fuer GFK-Rohrblaetter und die Turmspitze von blattgeregelten Windkraftanlagen.
Präoperative Lokalisationsdiagnostik und operative Ergebnisse bei 411 pHPT Operationen an einer Klinik für Endokrine Chirurgie
Rare earth-rich cadmium compounds RE 4 TCd (T = Co, Ru, and Rh) with Gd4RhIn type structure
Ion-irradiation-assisted tuning of phase transformations and physical properties in single crystalline Fe 7
Management of primary and renal hyperparathyroidism: guidelines from the German Association of Endocrine Surgeons (CAEK).
BACKGROUND AND AIMS
The purpose of this review is to provide updated recommendations for the surgical management of primary (pHPT) and renal (rHPT) hyperparathyroidism, formulating a new guideline of the German Association of Endocrine Surgeons (CAEK).
METHODS
Evidence-based recommendations for the diagnosis and therapy of pHPT and rHPT were assessed by a multidisciplinary panel using PubMed for a comprehensive literature search together with a structured consensus dialogue (S2k guideline of the Association of the German Scientific Medical Societies, AWMF).
RESULTS
During the last 20 years, a variety of new preoperative localization procedures, such as sestamibi-SPECT, 4D-CT, and various PET/CT procedures, were established for pHPT. High-resolution imaging, together with intraoperative parathyroid hormone (IOPTH) measurement, enabled focused or minimally invasive surgery to become the most favored surgical technique. Patients with pHPT and nonlocalizing imaging have a higher risk of multiglandular disease. Surgical therapy provides very high cure rates, with a clear relation to the surgeon's experience in parathyroid procedures. Reoperative parathyroidectomy, children with pHPT or familial forms, and parathyroid carcinoma are addressed and require special surgical expertise. A multidisciplinary team of experienced nephrologists, transplant, and endocrine surgeons should assess the diagnosis and treatment of renal HPT.
CONCLUSION
Surgery is the only curative treatment for pHPT and should be considered for all patients with pHPT. For rHPT, a more selective approach is required, and parathyroidectomy is indicated only when conservative treatment options fail. In parathyroid carcinoma, the adequacy of local resection influences local disease control
La<sub>6</sub>Pd<sub>13</sub>Cd<sub>4</sub> and Ce<sub>6</sub>Pd<sub>13</sub>Cd<sub>4</sub> with palladium-centred rare earth octahedra: synthesis, structure, and chemical bonding
he palladium-rich cadmium compounds La6Pd13Cd4 and Ce6Pd13Cd4 were synthesized by induction melting the elements in sealed tantalum ampoules and subsequent annealing. They were characterized by X-ray powder and single-crystal diffraction: Na16Ba6N type, ...